Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049625705> ?p ?o ?g. }
- W2049625705 endingPage "939" @default.
- W2049625705 startingPage "933" @default.
- W2049625705 abstract "CD157, a glycosylphosphatidylinositol (GPI)-anchored glycoprotein, has recently been shown to induce protein tyrosine phosphorylation in monocytes differentiated from HL-60 cells (mHL-60) in a ligand-dependent manner, but in a ligand-independent manner in stable CD157-transfected CHO (CHO/CD157) and MCA102 (MCA/CD157) fibroblasts [Cell Signal. 11 (1999) 891-897.]. Many GPI-anchored proteins need to be clustered by their ligands or antibodies to induce redistribution to caveolae and a concomitant activation of the associated signal-transducing proteins [Nature 387 (1997) 569-572.]. Here, we demonstrate that CD157, independent of antibody crosslinking, undergoes dimerization with disulfide bond formation and localization in caveolae in CHO/CD157 and MCA/CD157 fibroblasts. However, the native CD157 induced in mHL-60 cells remains a monomer form. The structural integrity of caveolae is required for the association of CD157 with caveolin and CD157-mediated tyrosine kinase signalling in the fibroblasts. We propose that an overexpression of CD157 could lead to its dimerization and relocation to caveolae and to further result in the initiation of signalling processes." @default.
- W2049625705 created "2016-06-24" @default.
- W2049625705 creator A5005234975 @default.
- W2049625705 creator A5043090528 @default.
- W2049625705 creator A5091250231 @default.
- W2049625705 date "2002-11-01" @default.
- W2049625705 modified "2023-09-25" @default.
- W2049625705 title "CD157 undergoes ligand-independent dimerization and colocalizes with caveolin in CHO and MCA102 fibroblasts" @default.
- W2049625705 cites W1514546358 @default.
- W2049625705 cites W1562084799 @default.
- W2049625705 cites W1630241876 @default.
- W2049625705 cites W1635401440 @default.
- W2049625705 cites W1663785932 @default.
- W2049625705 cites W1971696344 @default.
- W2049625705 cites W1981489609 @default.
- W2049625705 cites W1987571369 @default.
- W2049625705 cites W1988655498 @default.
- W2049625705 cites W1991419403 @default.
- W2049625705 cites W1993200072 @default.
- W2049625705 cites W2006892275 @default.
- W2049625705 cites W2007512974 @default.
- W2049625705 cites W2021027567 @default.
- W2049625705 cites W2022429307 @default.
- W2049625705 cites W2025018535 @default.
- W2049625705 cites W2037728674 @default.
- W2049625705 cites W2044960823 @default.
- W2049625705 cites W2048976197 @default.
- W2049625705 cites W2050105242 @default.
- W2049625705 cites W2050465028 @default.
- W2049625705 cites W2055698225 @default.
- W2049625705 cites W2067674514 @default.
- W2049625705 cites W2068908631 @default.
- W2049625705 cites W2073281086 @default.
- W2049625705 cites W2073925818 @default.
- W2049625705 cites W2078303408 @default.
- W2049625705 cites W2078862165 @default.
- W2049625705 cites W2082340361 @default.
- W2049625705 cites W2082614559 @default.
- W2049625705 cites W2088463353 @default.
- W2049625705 cites W2091707906 @default.
- W2049625705 cites W2092164532 @default.
- W2049625705 cites W2092437783 @default.
- W2049625705 cites W2099139945 @default.
- W2049625705 cites W2109923597 @default.
- W2049625705 cites W2116839542 @default.
- W2049625705 cites W2117763719 @default.
- W2049625705 cites W2121936687 @default.
- W2049625705 cites W2136449652 @default.
- W2049625705 cites W2139846514 @default.
- W2049625705 cites W2163790379 @default.
- W2049625705 cites W2164715751 @default.
- W2049625705 cites W2257876259 @default.
- W2049625705 doi "https://doi.org/10.1016/s0898-6568(02)00040-2" @default.
- W2049625705 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12220619" @default.
- W2049625705 hasPublicationYear "2002" @default.
- W2049625705 type Work @default.
- W2049625705 sameAs 2049625705 @default.
- W2049625705 citedByCount "6" @default.
- W2049625705 countsByYear W20496257052019 @default.
- W2049625705 crossrefType "journal-article" @default.
- W2049625705 hasAuthorship W2049625705A5005234975 @default.
- W2049625705 hasAuthorship W2049625705A5043090528 @default.
- W2049625705 hasAuthorship W2049625705A5091250231 @default.
- W2049625705 hasConcept C11960822 @default.
- W2049625705 hasConcept C170493617 @default.
- W2049625705 hasConcept C175656101 @default.
- W2049625705 hasConcept C185592680 @default.
- W2049625705 hasConcept C2780870201 @default.
- W2049625705 hasConcept C42362537 @default.
- W2049625705 hasConcept C49866891 @default.
- W2049625705 hasConcept C55493867 @default.
- W2049625705 hasConcept C62478195 @default.
- W2049625705 hasConcept C86803240 @default.
- W2049625705 hasConcept C95444343 @default.
- W2049625705 hasConceptScore W2049625705C11960822 @default.
- W2049625705 hasConceptScore W2049625705C170493617 @default.
- W2049625705 hasConceptScore W2049625705C175656101 @default.
- W2049625705 hasConceptScore W2049625705C185592680 @default.
- W2049625705 hasConceptScore W2049625705C2780870201 @default.
- W2049625705 hasConceptScore W2049625705C42362537 @default.
- W2049625705 hasConceptScore W2049625705C49866891 @default.
- W2049625705 hasConceptScore W2049625705C55493867 @default.
- W2049625705 hasConceptScore W2049625705C62478195 @default.
- W2049625705 hasConceptScore W2049625705C86803240 @default.
- W2049625705 hasConceptScore W2049625705C95444343 @default.
- W2049625705 hasIssue "11" @default.
- W2049625705 hasLocation W20496257051 @default.
- W2049625705 hasLocation W20496257052 @default.
- W2049625705 hasOpenAccess W2049625705 @default.
- W2049625705 hasPrimaryLocation W20496257051 @default.
- W2049625705 hasRelatedWork W101298169 @default.
- W2049625705 hasRelatedWork W1508828305 @default.
- W2049625705 hasRelatedWork W2044537148 @default.
- W2049625705 hasRelatedWork W2074278428 @default.
- W2049625705 hasRelatedWork W2074576820 @default.
- W2049625705 hasRelatedWork W2075183125 @default.
- W2049625705 hasRelatedWork W3030950172 @default.
- W2049625705 hasRelatedWork W3032393404 @default.