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• W2049663451 abstract "A Nafion-carbon nanotube-modified glassy carbon electrode (NAF-CNT-GCE) was developed for the determination of venlafaxine (VF) and desvenlafaxine (DVF). The electrochemical behavior of both these molecules was investigated employing cyclic voltammetry (CV), chronocoulometry (CC), electrochemical impedance spectroscopy (EIS) and adsorptive stripping differential pulse voltammetry (AdSDPV). The surface morphology of the electrodes has been studied by means of scanning electron microscopy (SEM). These studies revealed that the oxidation of VF and DVF is facilitated at NAF-CNT-GCE. After optimization of analytical conditions employing this electrode at pH 7.0 in Britton–Robinson buffer (0.05 M) for VF and pH 5.0 in acetate buffer (0.1 M) for DVF, the peak currents for both the molecules were found to vary linearly with their concentrations in the range of 3.81 × 10−8–6.22 × 10−5 M for VF and 5.33 × 10−8–3.58 × 10−5 M for DVF. The detection limits (S/N = 3) of 1.24 × 10−8 and 2.11 × 10−8 M were obtained for VF and DVF, respectively, using AdSDPV. The prepared modified electrode showed several advantages, such as simple preparation method, high sensitivity, very low detection limits and excellent reproducibility. The proposed method was employed for the determination of VF and DVF in pharmaceutical formulations, urine and blood serum samples." @default.
• W2049663451 created "2016-06-24" @default.
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• W2049663451 date "2011-04-01" @default.
• W2049663451 modified "2023-10-10" @default.
• W2049663451 title "Adsorptive stripping differential pulse voltammetric determination of venlafaxine and desvenlafaxine employing Nafion–carbon nanotube composite glassy carbon electrode" @default.
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• W2049663451 doi "https://doi.org/10.1016/j.electacta.2011.01.097" @default.
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