FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049670504> ?p ?o ?g. }

• W2049670504 endingPage "113" @default.
• W2049670504 startingPage "107" @default.
• W2049670504 abstract "We tested the genotoxicity of 3,5,4'-trihydroxystilbene (resveratrol), a polyphenolic phytoalexin found in grapes, in a bacterial reverse mutation assay, in vitro chromosome aberration (CA) test, in vitro micronucleus (MN) test, and sister chromatid exchange (SCE) test. Resveratrol was negative in the strains we used in the bacterial reverse mutation assay (S. typhimurium TA98 and TA100 and E. coli WP2uvrA) in the absence and presence of a microsomal metabolizing system. It induced structural CAs at 2.5-20 microg/ml and showed weak aneuploidy induction in a Chinese hamster lung (CHL) cell line. It induced MN cells and polynuclear and karyorrhectic cells after 48h treatments in the in vitro MN test. In the SCE test, resveratrol caused a clear cell-cycle delay; at 10 microg/ml, the cell cycle took twice as long as it did in the control. Resveratrol induced SCEs dose-dependently at up to 10 microg/ml, at which it increased SCE six-fold, and the number was almost as large as mitomycin C, a strong SCE inducer. No second mitoses were observed at 20 microg/ml even after 54h. Cell cycle analysis by FACScan indicated that resveratrol caused S phase arrest, and 48h treatment induced apoptosis. Our results suggest that resveratrol may preferentially induce SCE but not CA, that is, it may cause S phase arrest only when SCEs are induced." @default.
• W2049670504 created "2016-06-24" @default.
• W2049670504 creator A5017287832 @default.
• W2049670504 creator A5028681055 @default.
• W2049670504 creator A5049074816 @default.
• W2049670504 creator A5080975887 @default.
• W2049670504 creator A5081576616 @default.
• W2049670504 date "2001-07-01" @default.
• W2049670504 modified "2023-09-29" @default.
• W2049670504 title "Resveratrol, a naturally occurring polyphenol, induces sister chromatid exchanges in a Chinese hamster lung (CHL) cell line" @default.
• W2049670504 cites W1970240908 @default.
• W2049670504 cites W1971135728 @default.
• W2049670504 cites W1973195696 @default.
• W2049670504 cites W1979501382 @default.
• W2049670504 cites W1997651828 @default.
• W2049670504 cites W2005150513 @default.
• W2049670504 cites W2005156172 @default.
• W2049670504 cites W2006984368 @default.
• W2049670504 cites W2027355586 @default.
• W2049670504 cites W2031286860 @default.
• W2049670504 cites W2048883207 @default.
• W2049670504 cites W2060760516 @default.
• W2049670504 cites W2075690432 @default.
• W2049670504 cites W2094908670 @default.
• W2049670504 cites W2112560233 @default.
• W2049670504 cites W2151089147 @default.
• W2049670504 cites W2151891995 @default.
• W2049670504 cites W4242450681 @default.
• W2049670504 doi "https://doi.org/10.1016/s1383-5718(01)00184-x" @default.
• W2049670504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11423350" @default.
• W2049670504 hasPublicationYear "2001" @default.
• W2049670504 type Work @default.
• W2049670504 sameAs 2049670504 @default.
• W2049670504 citedByCount "46" @default.
• W2049670504 countsByYear W20496705042012 @default.
• W2049670504 countsByYear W20496705042013 @default.
• W2049670504 countsByYear W20496705042014 @default.
• W2049670504 countsByYear W20496705042015 @default.
• W2049670504 countsByYear W20496705042016 @default.
• W2049670504 countsByYear W20496705042017 @default.
• W2049670504 countsByYear W20496705042018 @default.
• W2049670504 countsByYear W20496705042019 @default.
• W2049670504 countsByYear W20496705042020 @default.
• W2049670504 countsByYear W20496705042021 @default.
• W2049670504 countsByYear W20496705042022 @default.
• W2049670504 countsByYear W20496705042023 @default.
• W2049670504 crossrefType "journal-article" @default.
• W2049670504 hasAuthorship W2049670504A5017287832 @default.
• W2049670504 hasAuthorship W2049670504A5028681055 @default.
• W2049670504 hasAuthorship W2049670504A5049074816 @default.
• W2049670504 hasAuthorship W2049670504A5080975887 @default.
• W2049670504 hasAuthorship W2049670504A5081576616 @default.
• W2049670504 hasConcept C104317684 @default.
• W2049670504 hasConcept C117632636 @default.
• W2049670504 hasConcept C153911025 @default.
• W2049670504 hasConcept C178790620 @default.
• W2049670504 hasConcept C185592680 @default.
• W2049670504 hasConcept C190283241 @default.
• W2049670504 hasConcept C202751555 @default.
• W2049670504 hasConcept C2776816829 @default.
• W2049670504 hasConcept C2777755551 @default.
• W2049670504 hasConcept C2778575167 @default.
• W2049670504 hasConcept C2778751241 @default.
• W2049670504 hasConcept C2778959862 @default.
• W2049670504 hasConcept C2779071816 @default.
• W2049670504 hasConcept C2781065037 @default.
• W2049670504 hasConcept C29537977 @default.
• W2049670504 hasConcept C29730261 @default.
• W2049670504 hasConcept C30481170 @default.
• W2049670504 hasConcept C36681516 @default.
• W2049670504 hasConcept C45080847 @default.
• W2049670504 hasConcept C523546767 @default.
• W2049670504 hasConcept C54355233 @default.
• W2049670504 hasConcept C55493867 @default.
• W2049670504 hasConcept C8502773 @default.
• W2049670504 hasConcept C86803240 @default.
• W2049670504 hasConceptScore W2049670504C104317684 @default.
• W2049670504 hasConceptScore W2049670504C117632636 @default.
• W2049670504 hasConceptScore W2049670504C153911025 @default.
• W2049670504 hasConceptScore W2049670504C178790620 @default.
• W2049670504 hasConceptScore W2049670504C185592680 @default.
• W2049670504 hasConceptScore W2049670504C190283241 @default.
• W2049670504 hasConceptScore W2049670504C202751555 @default.
• W2049670504 hasConceptScore W2049670504C2776816829 @default.
• W2049670504 hasConceptScore W2049670504C2777755551 @default.
• W2049670504 hasConceptScore W2049670504C2778575167 @default.
• W2049670504 hasConceptScore W2049670504C2778751241 @default.
• W2049670504 hasConceptScore W2049670504C2778959862 @default.
• W2049670504 hasConceptScore W2049670504C2779071816 @default.
• W2049670504 hasConceptScore W2049670504C2781065037 @default.
• W2049670504 hasConceptScore W2049670504C29537977 @default.
• W2049670504 hasConceptScore W2049670504C29730261 @default.
• W2049670504 hasConceptScore W2049670504C30481170 @default.
• W2049670504 hasConceptScore W2049670504C36681516 @default.
• W2049670504 hasConceptScore W2049670504C45080847 @default.
• W2049670504 hasConceptScore W2049670504C523546767 @default.
• W2049670504 hasConceptScore W2049670504C54355233 @default.
• W2049670504 hasConceptScore W2049670504C55493867 @default.

• next