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• W2049674778 abstract "A lthough abdominal pain is a frequent manifestation of systemic lupus erythematosus (SLE), occurring in up to 20 percent of the patients in some series, clinically significant bowel vasculitis remains uncommon. It is, however, one of the most devastating complications of lupus. The mortality rate in the largest published series [l] was slightly greater than 50 percent. This figure reflects in part the difficulty in establishing the diagnosis early enough for treatment to revekse the process. But it is also due in part to the therapeutic inadequacy of high-dose steroids, the most commonly used treatment for this condition. This report describes for the first time a patient with SLE complicated by life-threatening gastrointestinal bleeding from widespread bowel vasculitis in whom treatment with high-dose parenteral steroids failed and who then gradually recovered following the administration of pulse intravenous cyclophosphamide. In addition, she is the sixth lupus patient reported in the English literature in whom colonic pneumatosis cystoides intestinalis has developed. This complication also resolved with therapy." @default.
• W2049674778 created "2016-06-24" @default.
• W2049674778 creator A5090368322 @default.
• W2049674778 date "1988-10-01" @default.
• W2049674778 modified "2023-10-18" @default.
• W2049674778 title "Gastrointestinal vasculitis and pneumatosis intestinalis due to systemic lupus erythematosus: successful treatment with pulse intravenous cyclophosphamide" @default.
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• W2049674778 doi "https://doi.org/10.1016/s0002-9343(88)80096-2" @default.
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