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• W2049678088 abstract "Previous studies have reported cerebellar abnormalities or static ataxia associated with risk for chronic use of alcohol and drugs. Adverse childhood experience is another strong risk factor for later substance abuse. We therefore sought to ascertain the relationship between morphological phenotypes of the lingula (lobule I) of the anterior cerebellar vermis, and exposure to emotional (EM) versus physical (PM) maltreatment, on the degree of ongoing alcohol or drug use. The study design consisted of a cross-sectional in vivo neuroimaging study, utilizing retrospective assessment of maltreatment history and self-reports of alcohol and substance use. Study participants were 153 subjects (54 M/99F, 21.9 ± 2.2 years) selected for imaging from a database of 1,402 community participants 18–25 years of age, who completed a detailed online screening instrument and met rigorous inclusion/exclusion criteria. Subjects were exposed to only physical abuse or harsh corporal punishment (HCP; PM group, n = 37) and parental verbal abuse and/or witnessing domestic violence (EM group, n = 58) or had no history of maltreatment or axis I disorders (n = 58). The main outcome measures consisted of the gray matter volume of lobule I as measured by manual tracing, number and type of alcoholic beverages consumed during a drinking session, number of sessions per month, and monthly drug use, along with family history of drug and alcohol abuse. Lingula thickness was not attenuated by alcohol use or maltreatment history. However, increased lingula thickness was associated with greater consumption of drugs and hard liquor, particularly in physically maltreated subjects who consumed 2.5- and 2.7-fold more alcohol and used drugs 6.1- and 7.8-fold more frequently than controls or EM subjects, respectively. In conclusion, physical maltreatment was observed to interact with cerebellar morphology resulting in a strong association with alcohol and substance use. Lingula thickness may represent a novel, experientially sensitive, phenotypic risk factor for enhanced alcohol and drug use that perhaps modulates sensitivity to these agents." @default.
• W2049678088 created "2016-06-24" @default.
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• W2049678088 creator A5028031641 @default.
• W2049678088 creator A5050756390 @default.
• W2049678088 creator A5081926662 @default.
• W2049678088 date "2009-10-28" @default.
• W2049678088 modified "2023-10-16" @default.
• W2049678088 title "Cerebellar Lingula Size and Experiential Risk Factors Associated with High Levels of Alcohol and Drug Use in Young Adults" @default.
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• W2049678088 cites W1826521770 @default.
• W2049678088 cites W1841749037 @default.
• W2049678088 cites W1963749842 @default.
• W2049678088 cites W1964164372 @default.
• W2049678088 cites W1968821982 @default.
• W2049678088 cites W1977781112 @default.
• W2049678088 cites W1978170666 @default.
• W2049678088 cites W1983904931 @default.
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• W2049678088 cites W1986841363 @default.
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• W2049678088 cites W1996320719 @default.
• W2049678088 cites W1996957680 @default.
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• W2049678088 cites W2002942099 @default.
• W2049678088 cites W2007858932 @default.
• W2049678088 cites W2009892798 @default.
• W2049678088 cites W2011320995 @default.
• W2049678088 cites W2015931865 @default.
• W2049678088 cites W2015988706 @default.
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• W2049678088 cites W2022235619 @default.
• W2049678088 cites W2035211330 @default.
• W2049678088 cites W2042372462 @default.
• W2049678088 cites W2051922817 @default.
• W2049678088 cites W2051994523 @default.
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• W2049678088 cites W2054132496 @default.
• W2049678088 cites W2056602832 @default.
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• W2049678088 cites W2062257614 @default.
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• W2049678088 cites W2062419177 @default.
• W2049678088 cites W2069691999 @default.
• W2049678088 cites W2081050837 @default.
• W2049678088 cites W2082429473 @default.
• W2049678088 cites W2082888727 @default.
• W2049678088 cites W2084000967 @default.
• W2049678088 cites W2085389018 @default.
• W2049678088 cites W2085907824 @default.
• W2049678088 cites W2093064538 @default.
• W2049678088 cites W2094010860 @default.
• W2049678088 cites W2095448564 @default.
• W2049678088 cites W2095529953 @default.
• W2049678088 cites W2097139733 @default.
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• W2049678088 cites W2104170262 @default.
• W2049678088 cites W2106435120 @default.
• W2049678088 cites W2116806046 @default.
• W2049678088 cites W2121592433 @default.
• W2049678088 cites W2123547278 @default.
• W2049678088 cites W2127679982 @default.
• W2049678088 cites W2130189043 @default.
• W2049678088 cites W2132964818 @default.
• W2049678088 cites W2144085872 @default.
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• W2049678088 cites W2162709024 @default.
• W2049678088 cites W2163989393 @default.
• W2049678088 cites W2166372248 @default.
• W2049678088 cites W2171976136 @default.
• W2049678088 cites W2338719804 @default.
• W2049678088 cites W4254026523 @default.
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• W2049678088 doi "https://doi.org/10.1007/s12311-009-0141-5" @default.
• W2049678088 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3928065" @default.
• W2049678088 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19859774" @default.
• W2049678088 hasPublicationYear "2009" @default.
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