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- W2049717811 abstract "Mouse testes were cultured in a saturated solution of caffeine. The effects are positive: stickiness of the chromosomes, clumping of the chromosomes and chromatin extrusion from the nuclei — or negative: gap formation and fragmentation of the chromosomes and vacuolar extrusion of material from the nuclei. In positive action caffeine acts on the extragenic DNA. In the negative action it destroys the Feulgen reactivity of the DNA, thus breaking down certain nucleotides. By influencing the supply of certain nucleotides caffeine may be involved in mutagenesis and chromosome breaks and their reunion." @default.
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- W2049717811 title "Immediate effects of chemicals on mouse chromosomes" @default.
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- W2049717811 doi "https://doi.org/10.1016/0303-2647(71)90007-4" @default.
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