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- W2049735306 abstract "In native Xenopus oocytes, injection of guanosine 5′-O-(3-thiotriphosphate) (GTPγS) (30 mM, 5 nl) did not induce Cl− current in 11 out of 22 oocytes. Injection of increased concentration of GTPgS (100 mM, 5 nl) into the oocytes induced Cl− currents in 16 out of 17 oocytes; however, the size of the induced currents was extremely varied. In oocytes overexpressing Gqα,GTPγS (30 mM, 5 nl) faithfully evoked Ca2+-activated Cl− currents. These results indicate that heterogeneous expression of Gqα in Xenopus oocytes provides a useful system for studying the functional roles of Gqa in regulating cellular events." @default.
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- W2049735306 date "2001-01-01" @default.
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- W2049735306 title "GTPγS-Induced Ca2+ Activated Cl− Currents: Its Stable Induction by Gqα Overexpression in Xenopus Oocytes" @default.
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- W2049735306 doi "https://doi.org/10.1254/jjp.86.244" @default.
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