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• W2049737029 abstract "The aim of the present study was to evaluate the importance of a multidisciplinary approach on increasing the response ratio expectation to mandibular advancing device (MAD) therapy in patients with obstructive sleep apnoea syndrome, especially in severe cases. Forty-two mild-to-severe OSAS patients were selected, after comprehensive evaluation by neurologists, otorhinolaryngologists and orthodontists, and treated with a Somnodent® device. Six months later, a polysomnographic exam with the MAD in situ was performed. The paired t-test evaluated the effectiveness of therapy and the results were compared with data from systematic reviews. The average treatment response was statistically significant for the apnoea/hypopnea index (AHI) and oxygen desaturation index and was higher than the outcomes presented in literature. An optimum therapy response (AHI < 5) was observed in 53% of patients (40% in severe OSAS) and a good response (AHI < 10) in 73% of patients (50% in severe OSAS). The Somnodent® device was effective and the multidisciplinary patient selection improved the response ratio compared to that reported by previous systematic reviews. Lo scopo dello studio è quello di valutare l'impatto dell'approccio multidisciplinare nel determinare la percentuale di risposta alla terapia con dispositivi ad avanzamento mandibolare nei pazienti affetti da OSAS, anche di severa entità. Dopo una valutazione che ha compreso una visita neurologica, otorinolaringoiatrica ed ortodontica, 42 pazienti sono stati selezionati e sono stati trattati con un dispositivo ad avanzamento mandibolare (MAD) a tipo Somnodent®. A 6 mesi dalla consegna del MAD, i pazienti sono stati sottoposti ad un esame polisonnografico con il dispositivo in situ. Un paired t-test è stato utilizzato per valutare l'efficacia alla terapia e le percentuali di risposta ottima (AHI < 5) e buona (AHI < 10) ottenute sono state confrontate con quelle riportate dalle revisioni sistematiche presenti in letteratura. Sono state raggiunte una risposta ottima nel 53% dei pazienti (40% nei pazienti gravi) e una risposta buona nel 73% dei pazienti (50% nei pazienti gravi). I risultati ottenuti confermano l'efficacia del Somnodent® e dimostrano come la selezione multidisciplinare del paziente possa determinare un'incremento della percentuale di risposta alla terapia odontoiatrica, rispetto a quella riferita dalla revisione sistematica della letteratura." @default.
• W2049737029 created "2016-06-24" @default.
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• W2049737029 date "2013-10-01" @default.
• W2049737029 modified "2023-09-23" @default.
• W2049737029 title "The impact of a multidisciplinary approach on response rate of mandibular advancing device therapy in patients with obstructive sleep apnoea syndrome." @default.
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