FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049764675> ?p ?o ?g. }

• W2049764675 endingPage "780" @default.
• W2049764675 startingPage "769" @default.
• W2049764675 abstract "Nonalcoholic fatty liver disease (NAFLD) is the most common liver disorder in the United States; however, few data are available about racial and ethnic variation. We investigated relationships between ethnicity, NAFLD severity, metabolic derangements, and sociodemographic characteristics in a well-characterized cohort of adults with biopsy-proven NAFLD. Data were analyzed from 1,026 adults (≥18 years) in the Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN) from 2004 to 2008, for whom liver histology data were available within 6 months of enrollment. Associations between ethnicity (i.e., Latino versus non-Latino white) and NAFLD severity (i.e., NASH versus non-NASH histology and mild versus advanced fibrosis) were explored with multiple logistic regression analysis. We also investigated effect modification of ethnicity on metabolic derangements for NAFLD severity. Within the NASH CRN, 77% (N = 785) were non-Latino white and 12% (N = 118) were Latino. Sixty-one percent (N = 628) had NASH histology and 28% (N = 291) had advanced fibrosis. Latinos with NASH were younger, performed less physical activity, and had higher carbohydrate intake, compared to non-Latino whites with NASH. Gender, diabetes, hypertension, hypertriglyceridemia, aspartate aminotransferase (AST), platelets, and the homeostasis model assessment of insulin resistance (HOMA-IR) were significantly associated with NASH. Age, gender, AST, alanine aminotransferase, alkaline phosphatase, platelets, total cholesterol, hypertension, and HOMA-IR, but not ethnicity, were significantly associated with advanced fibrosis. The effect of HOMA-IR on the risk of NASH was modified by ethnicity: HOMA-IR was not a significant risk factor for NASH among Latinos (odds ratio [OR] = 0.93; 95% confidence interval [CI]: 0.85-1.02), but was significant among non-Latino whites (OR, 1.06; 95% CI: 1.01-1.11).Metabolic risk factors and sociodemographic characteristics associated with NASH differ by ethnicity. Additional insights into NASH pathogenesis may come from further studies focused on understanding ethnic differences in this disease." @default.
• W2049764675 created "2016-06-24" @default.
• W2049764675 creator A5000371862 @default.
• W2049764675 creator A5013443210 @default.
• W2049764675 creator A5041931283 @default.
• W2049764675 creator A5055603363 @default.
• W2049764675 creator A5058699357 @default.
• W2049764675 creator A5065080959 @default.
• W2049764675 creator A5072533299 @default.
• W2049764675 creator A5074870604 @default.
• W2049764675 date "2012-02-23" @default.
• W2049764675 modified "2023-10-11" @default.
• W2049764675 title "Ethnicity and nonalcoholic fatty liver disease" @default.
• W2049764675 cites W1501531968 @default.
• W2049764675 cites W1579290 @default.
• W2049764675 cites W1990010616 @default.
• W2049764675 cites W2006560627 @default.
• W2049764675 cites W2013654496 @default.
• W2049764675 cites W2017511982 @default.
• W2049764675 cites W2025163736 @default.
• W2049764675 cites W2045084840 @default.
• W2049764675 cites W2050367310 @default.
• W2049764675 cites W2059251195 @default.
• W2049764675 cites W2062812115 @default.
• W2049764675 cites W2066472395 @default.
• W2049764675 cites W2067740038 @default.
• W2049764675 cites W2072390396 @default.
• W2049764675 cites W2075571367 @default.
• W2049764675 cites W2089535377 @default.
• W2049764675 cites W2098555833 @default.
• W2049764675 cites W2111951337 @default.
• W2049764675 cites W2125963555 @default.
• W2049764675 cites W2144852094 @default.
• W2049764675 cites W2153909270 @default.
• W2049764675 cites W2157511971 @default.
• W2049764675 cites W2170328050 @default.
• W2049764675 cites W4237819424 @default.
• W2049764675 doi "https://doi.org/10.1002/hep.24726" @default.
• W2049764675 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3278533" @default.
• W2049764675 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21987488" @default.
• W2049764675 hasPublicationYear "2012" @default.
• W2049764675 type Work @default.
• W2049764675 sameAs 2049764675 @default.
• W2049764675 citedByCount "174" @default.
• W2049764675 countsByYear W20497646752012 @default.
• W2049764675 countsByYear W20497646752013 @default.
• W2049764675 countsByYear W20497646752014 @default.
• W2049764675 countsByYear W20497646752015 @default.
• W2049764675 countsByYear W20497646752016 @default.
• W2049764675 countsByYear W20497646752017 @default.
• W2049764675 countsByYear W20497646752018 @default.
• W2049764675 countsByYear W20497646752019 @default.
• W2049764675 countsByYear W20497646752020 @default.
• W2049764675 countsByYear W20497646752021 @default.
• W2049764675 countsByYear W20497646752022 @default.
• W2049764675 countsByYear W20497646752023 @default.
• W2049764675 crossrefType "journal-article" @default.
• W2049764675 hasAuthorship W2049764675A5000371862 @default.
• W2049764675 hasAuthorship W2049764675A5013443210 @default.
• W2049764675 hasAuthorship W2049764675A5041931283 @default.
• W2049764675 hasAuthorship W2049764675A5055603363 @default.
• W2049764675 hasAuthorship W2049764675A5058699357 @default.
• W2049764675 hasAuthorship W2049764675A5065080959 @default.
• W2049764675 hasAuthorship W2049764675A5072533299 @default.
• W2049764675 hasAuthorship W2049764675A5074870604 @default.
• W2049764675 hasBestOaLocation W20497646751 @default.
• W2049764675 hasConcept C126322002 @default.
• W2049764675 hasConcept C134018914 @default.
• W2049764675 hasConcept C156957248 @default.
• W2049764675 hasConcept C2775934546 @default.
• W2049764675 hasConcept C2776954865 @default.
• W2049764675 hasConcept C2777391703 @default.
• W2049764675 hasConcept C2777766500 @default.
• W2049764675 hasConcept C2778535154 @default.
• W2049764675 hasConcept C2778772119 @default.
• W2049764675 hasConcept C2779134260 @default.
• W2049764675 hasConcept C2779306644 @default.
• W2049764675 hasConcept C71924100 @default.
• W2049764675 hasConcept C90924648 @default.
• W2049764675 hasConceptScore W2049764675C126322002 @default.
• W2049764675 hasConceptScore W2049764675C134018914 @default.
• W2049764675 hasConceptScore W2049764675C156957248 @default.
• W2049764675 hasConceptScore W2049764675C2775934546 @default.
• W2049764675 hasConceptScore W2049764675C2776954865 @default.
• W2049764675 hasConceptScore W2049764675C2777391703 @default.
• W2049764675 hasConceptScore W2049764675C2777766500 @default.
• W2049764675 hasConceptScore W2049764675C2778535154 @default.
• W2049764675 hasConceptScore W2049764675C2778772119 @default.
• W2049764675 hasConceptScore W2049764675C2779134260 @default.
• W2049764675 hasConceptScore W2049764675C2779306644 @default.
• W2049764675 hasConceptScore W2049764675C71924100 @default.
• W2049764675 hasConceptScore W2049764675C90924648 @default.
• W2049764675 hasIssue "3" @default.
• W2049764675 hasLocation W20497646751 @default.
• W2049764675 hasLocation W20497646752 @default.
• W2049764675 hasLocation W20497646753 @default.
• W2049764675 hasLocation W20497646754 @default.
• W2049764675 hasOpenAccess W2049764675 @default.

• next