Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049819489> ?p ?o ?g. }
- W2049819489 endingPage "475" @default.
- W2049819489 startingPage "468" @default.
- W2049819489 abstract "Aims: The aims of this study were to assess bone mineral density (BMD) and content (BMC), osteocalcin, serum telopeptide, PTH and vitamin D in alcoholics, and to determine if a 6-month period of abstinence leads to changes in these parameters. Methods: Serum osteocalcin, insulin-like growth factor 1 (IGF-1), telopeptide (40 patients) and 1,25 dihydroxyvitamin D, were measured in 28 controls and 77 alcoholic patients, 48 of whom were evaluated again 6 months later. All patients underwent whole-body assessment of BMD by a Hologic QDR-2000 (Waltham, MA, USA) bone densitometer, at the beginning of the study and 6 months later. Results: Patients showed higher serum telopeptide levels (0.59 ± 0.40 versus 0.19 ± 0.10 nmol/100 ml, P < 0.001), lower IGF-1 [median = 49, interquartile range (IQR) = 31–121 ng/ml versus 135, IQR = 116–237 ng/ml, P < 0.001], vitamin D [26.5, IQR = 17.0–37.8 pg/ml versus 82.4 (IQR = 60.9–107.4 pg/ml, P < 0.001] and osteocalcin (2.1, IQR = 1.1–3.6 ng/ml versus 6.65, IQR = 4.9–8.8 ng/ml, P < 0.001) than those in controls. Patients also showed lower BMD values, Z- and T-scores at many levels of the skeleton and reduced total BMC. After 6 months, those who continued drinking showed a loss of bone mass, whereas those who abstained showed either no change or increase, differences being especially marked at pelvis, right arm and total BMD and BMC. Simultaneously, abstainers showed a significant increase in osteocalcin (versus a decrease among those who continued drinking). Serum telopeptide increased in both groups. Conclusion: Ethanol consumption leads to osteopenia, and decreased serum osteocalcin, which improve with abstinence, whereas those who continue drinking show a worsening of both parameters." @default.
- W2049819489 created "2016-06-24" @default.
- W2049819489 creator A5015126977 @default.
- W2049819489 creator A5049198183 @default.
- W2049819489 creator A5051995928 @default.
- W2049819489 creator A5060522670 @default.
- W2049819489 creator A5069623063 @default.
- W2049819489 creator A5077965873 @default.
- W2049819489 creator A5082060168 @default.
- W2049819489 creator A5090032313 @default.
- W2049819489 date "2009-06-17" @default.
- W2049819489 modified "2023-10-10" @default.
- W2049819489 title "Osteopenia in Alcoholics: Effect of Alcohol Abstinence" @default.
- W2049819489 cites W1974357504 @default.
- W2049819489 cites W1976337601 @default.
- W2049819489 cites W1985601827 @default.
- W2049819489 cites W1985792013 @default.
- W2049819489 cites W1990820241 @default.
- W2049819489 cites W1991165382 @default.
- W2049819489 cites W2002247919 @default.
- W2049819489 cites W2015866062 @default.
- W2049819489 cites W2024852998 @default.
- W2049819489 cites W2025043156 @default.
- W2049819489 cites W2030570009 @default.
- W2049819489 cites W2050144748 @default.
- W2049819489 cites W2071502893 @default.
- W2049819489 cites W2076727167 @default.
- W2049819489 cites W2083215563 @default.
- W2049819489 cites W2085172730 @default.
- W2049819489 cites W2087262506 @default.
- W2049819489 cites W2088793615 @default.
- W2049819489 cites W2089866195 @default.
- W2049819489 cites W2092593001 @default.
- W2049819489 cites W2103689875 @default.
- W2049819489 cites W2105592227 @default.
- W2049819489 cites W2131435800 @default.
- W2049819489 cites W2148448684 @default.
- W2049819489 cites W2156297698 @default.
- W2049819489 cites W2172164507 @default.
- W2049819489 cites W2272554473 @default.
- W2049819489 cites W2321380288 @default.
- W2049819489 cites W4235447297 @default.
- W2049819489 doi "https://doi.org/10.1093/alcalc/agp038" @default.
- W2049819489 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19535494" @default.
- W2049819489 hasPublicationYear "2009" @default.
- W2049819489 type Work @default.
- W2049819489 sameAs 2049819489 @default.
- W2049819489 citedByCount "81" @default.
- W2049819489 countsByYear W20498194892012 @default.
- W2049819489 countsByYear W20498194892013 @default.
- W2049819489 countsByYear W20498194892014 @default.
- W2049819489 countsByYear W20498194892015 @default.
- W2049819489 countsByYear W20498194892016 @default.
- W2049819489 countsByYear W20498194892017 @default.
- W2049819489 countsByYear W20498194892018 @default.
- W2049819489 countsByYear W20498194892019 @default.
- W2049819489 countsByYear W20498194892020 @default.
- W2049819489 countsByYear W20498194892021 @default.
- W2049819489 countsByYear W20498194892022 @default.
- W2049819489 countsByYear W20498194892023 @default.
- W2049819489 crossrefType "journal-article" @default.
- W2049819489 hasAuthorship W2049819489A5015126977 @default.
- W2049819489 hasAuthorship W2049819489A5049198183 @default.
- W2049819489 hasAuthorship W2049819489A5051995928 @default.
- W2049819489 hasAuthorship W2049819489A5060522670 @default.
- W2049819489 hasAuthorship W2049819489A5069623063 @default.
- W2049819489 hasAuthorship W2049819489A5077965873 @default.
- W2049819489 hasAuthorship W2049819489A5082060168 @default.
- W2049819489 hasAuthorship W2049819489A5090032313 @default.
- W2049819489 hasBestOaLocation W20498194891 @default.
- W2049819489 hasConcept C119060515 @default.
- W2049819489 hasConcept C124490489 @default.
- W2049819489 hasConcept C125870589 @default.
- W2049819489 hasConcept C126322002 @default.
- W2049819489 hasConcept C131075544 @default.
- W2049819489 hasConcept C134018914 @default.
- W2049819489 hasConcept C160160445 @default.
- W2049819489 hasConcept C181199279 @default.
- W2049819489 hasConcept C185592680 @default.
- W2049819489 hasConcept C2776541429 @default.
- W2049819489 hasConcept C2776886416 @default.
- W2049819489 hasConcept C2777083390 @default.
- W2049819489 hasConcept C2779329777 @default.
- W2049819489 hasConcept C55493867 @default.
- W2049819489 hasConcept C71924100 @default.
- W2049819489 hasConceptScore W2049819489C119060515 @default.
- W2049819489 hasConceptScore W2049819489C124490489 @default.
- W2049819489 hasConceptScore W2049819489C125870589 @default.
- W2049819489 hasConceptScore W2049819489C126322002 @default.
- W2049819489 hasConceptScore W2049819489C131075544 @default.
- W2049819489 hasConceptScore W2049819489C134018914 @default.
- W2049819489 hasConceptScore W2049819489C160160445 @default.
- W2049819489 hasConceptScore W2049819489C181199279 @default.
- W2049819489 hasConceptScore W2049819489C185592680 @default.
- W2049819489 hasConceptScore W2049819489C2776541429 @default.
- W2049819489 hasConceptScore W2049819489C2776886416 @default.
- W2049819489 hasConceptScore W2049819489C2777083390 @default.
- W2049819489 hasConceptScore W2049819489C2779329777 @default.