Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049879934> ?p ?o ?g. }
- W2049879934 endingPage "2340" @default.
- W2049879934 startingPage "2335" @default.
- W2049879934 abstract "Immunoperoxidase staining for carcinoembryonic antigen (CEA) was performed on the tumors of 88 patients with epithelial ovarian cystadenocarcinomas treated at the University of Kentucky Medical Center from 1962 to 1975. Pretherapy plasma CEA determinations were obtained in 45 of these patients, and 40 had serial plasma CEA measurements following therapy. Cyst fluid CEA concentrations were measured in 14 patients. Immunoperoxidase staining indicative of a tissue CEA concentration of at least 3 μg/g was present in 21% of mucinons tumors and 2 % of serous tumors, representing a significant (p < 0.01) difference between these two cell types. Cyst fluid CEA concentrations were above 1 μg/ml in 75% of mucinous cystadenocarcinomas but in no serous tumors. Plasma CEA levels were related both to tissue and cyst fluid CEA concentrations and to the extent or stage of disease. Plasma CEA was highest in poorly differentiated mucinous tumors. All patients with progressively increasing plasma CEA levels developed recurrent ovarian cancer and died of their disease. Nine patients developed recurrent cancer despite having normal plasma CEA values, but none of the tumors of these patients contained measurable concentrations of CEA. Serial plasma CEA determinations most accurately reflected the clinical status of disease in those patients whose tumors contained high levels of antigen. Pretherapy plasma and tumor levels of CEA should be measured in order to identify those patients in whom serial plasma CEA determinations following therapy will be useful to monitor the effects of therapy." @default.
- W2049879934 created "2016-06-24" @default.
- W2049879934 creator A5003890903 @default.
- W2049879934 creator A5015512498 @default.
- W2049879934 creator A5043569662 @default.
- W2049879934 creator A5053698828 @default.
- W2049879934 creator A5063751141 @default.
- W2049879934 date "1978-06-01" @default.
- W2049879934 modified "2023-10-10" @default.
- W2049879934 title "Carcinoembryonic antigen in ovarian epithelial cystadenocarcinomas.The prognostic value of tumor and serial plasma determinations" @default.
- W2049879934 cites W1504496277 @default.
- W2049879934 cites W1546183494 @default.
- W2049879934 cites W1564552887 @default.
- W2049879934 cites W1721066778 @default.
- W2049879934 cites W1827777032 @default.
- W2049879934 cites W1864858998 @default.
- W2049879934 cites W1970512665 @default.
- W2049879934 cites W2003137675 @default.
- W2049879934 cites W2003649909 @default.
- W2049879934 cites W2004102690 @default.
- W2049879934 cites W2008054395 @default.
- W2049879934 cites W2038722446 @default.
- W2049879934 cites W2044685494 @default.
- W2049879934 cites W2048012888 @default.
- W2049879934 cites W2053551981 @default.
- W2049879934 cites W2058137569 @default.
- W2049879934 cites W2075169300 @default.
- W2049879934 cites W2088670330 @default.
- W2049879934 cites W2092457869 @default.
- W2049879934 cites W2121988246 @default.
- W2049879934 cites W2167630194 @default.
- W2049879934 cites W2200379135 @default.
- W2049879934 cites W2337822771 @default.
- W2049879934 doi "https://doi.org/10.1002/1097-0142(197806)41:6<2335::aid-cncr2820410636>3.0.co;2-f" @default.
- W2049879934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/350376" @default.
- W2049879934 hasPublicationYear "1978" @default.
- W2049879934 type Work @default.
- W2049879934 sameAs 2049879934 @default.
- W2049879934 citedByCount "55" @default.
- W2049879934 countsByYear W20498799342015 @default.
- W2049879934 crossrefType "journal-article" @default.
- W2049879934 hasAuthorship W2049879934A5003890903 @default.
- W2049879934 hasAuthorship W2049879934A5015512498 @default.
- W2049879934 hasAuthorship W2049879934A5043569662 @default.
- W2049879934 hasAuthorship W2049879934A5053698828 @default.
- W2049879934 hasAuthorship W2049879934A5063751141 @default.
- W2049879934 hasBestOaLocation W20498799341 @default.
- W2049879934 hasConcept C121608353 @default.
- W2049879934 hasConcept C126322002 @default.
- W2049879934 hasConcept C128102431 @default.
- W2049879934 hasConcept C142724271 @default.
- W2049879934 hasConcept C150173356 @default.
- W2049879934 hasConcept C159654299 @default.
- W2049879934 hasConcept C203014093 @default.
- W2049879934 hasConcept C2777387746 @default.
- W2049879934 hasConcept C2778164203 @default.
- W2049879934 hasConcept C2778324911 @default.
- W2049879934 hasConcept C2780223747 @default.
- W2049879934 hasConcept C2780427987 @default.
- W2049879934 hasConcept C2780597408 @default.
- W2049879934 hasConcept C2780964533 @default.
- W2049879934 hasConcept C542903549 @default.
- W2049879934 hasConcept C71924100 @default.
- W2049879934 hasConceptScore W2049879934C121608353 @default.
- W2049879934 hasConceptScore W2049879934C126322002 @default.
- W2049879934 hasConceptScore W2049879934C128102431 @default.
- W2049879934 hasConceptScore W2049879934C142724271 @default.
- W2049879934 hasConceptScore W2049879934C150173356 @default.
- W2049879934 hasConceptScore W2049879934C159654299 @default.
- W2049879934 hasConceptScore W2049879934C203014093 @default.
- W2049879934 hasConceptScore W2049879934C2777387746 @default.
- W2049879934 hasConceptScore W2049879934C2778164203 @default.
- W2049879934 hasConceptScore W2049879934C2778324911 @default.
- W2049879934 hasConceptScore W2049879934C2780223747 @default.
- W2049879934 hasConceptScore W2049879934C2780427987 @default.
- W2049879934 hasConceptScore W2049879934C2780597408 @default.
- W2049879934 hasConceptScore W2049879934C2780964533 @default.
- W2049879934 hasConceptScore W2049879934C542903549 @default.
- W2049879934 hasConceptScore W2049879934C71924100 @default.
- W2049879934 hasIssue "6" @default.
- W2049879934 hasLocation W20498799341 @default.
- W2049879934 hasLocation W20498799342 @default.
- W2049879934 hasOpenAccess W2049879934 @default.
- W2049879934 hasPrimaryLocation W20498799341 @default.
- W2049879934 hasRelatedWork W1632281714 @default.
- W2049879934 hasRelatedWork W1965371802 @default.
- W2049879934 hasRelatedWork W2055433545 @default.
- W2049879934 hasRelatedWork W2064080465 @default.
- W2049879934 hasRelatedWork W2374792925 @default.
- W2049879934 hasRelatedWork W2394880376 @default.
- W2049879934 hasRelatedWork W2399091299 @default.
- W2049879934 hasRelatedWork W2408962782 @default.
- W2049879934 hasRelatedWork W2410251865 @default.
- W2049879934 hasRelatedWork W2473496985 @default.
- W2049879934 hasVolume "41" @default.
- W2049879934 isParatext "false" @default.
- W2049879934 isRetracted "false" @default.
- W2049879934 magId "2049879934" @default.