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- W2049896670 abstract "The irreversible swelling caused by P1 is abolished by amounts of EDTA or EGTA equal to twice the content of mitochondrial Ca2+. Addition of Ca2+ restores the swelling process. The swelling effect of Ca2+ has a different Km from the respiratory stimulation by Ca2+. The swelling effect of Ca2+ is inhibited competitively by Mg2+. The release of Ca2+ from the mitochondria, following the addition of Pi or other anions, appears to be secondary to a swelling effect. When the swelling effect is inhibited, no release of Ca2+ follows the addition of the anion. Ca2+ is released from the mitochondria also when swelling occurs in the absence of anions. When swelling is inhibited by oligomycin or Mg2+, addition of Pi increases the amount of Ca2+ taken up by the mitochondria." @default.
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- W2049896670 date "1966-01-01" @default.
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- W2049896670 title "Swelling and shrinkage phenomena in liver mitochondria III. Irreversible swelling induced by inorganic phosphate and Ca2+" @default.
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- W2049896670 doi "https://doi.org/10.1016/s0926-6593(66)80002-4" @default.
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