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- W2049902893 abstract "We measured protein S (PS) activity in a large group of Japanese subjects to study the frequency of PS deficiency. The study group comprised 213 men, ages 18-58 years, and 179 women, ages 18-60 years. PS activity in the total 392 subjects was 58-135% (mean +/- 2 SD), 65-135% in the men and 54-120% in the women. The men showed significantly higher levels of PS activity than the women (p<0.001). We identified 8 subjects (4 men and 4 women) in whom PS activity was lower than the mean-2SD for men and women, respectively. Moreover, we examined the classifications of PS deficiency. The frequency of PS deficiency in this study was 2.04% (Type I: 0.51%, Type II: 1.02%, Type III: 0.51%). Based on our findings, it would appear that the frequency of Type II PS deficiency in the Japanese population is approximately 1%. The screening of PS decrease should be judged by activity." @default.
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- W2049902893 date "2000-12-01" @default.
- W2049902893 modified "2023-09-25" @default.
- W2049902893 title "Frequency of Protein S Deficiency in General Japanese Population" @default.
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- W2049902893 doi "https://doi.org/10.1016/s0049-3848(00)00337-6" @default.
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