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- W2049912387 abstract "Adenomas of the major duodenal papilla have the potential to undergo malignant transformation. Although surgical resection has historically been the standard treatment for ampullary neoplasms, endoscopic resection (ampullectomy) of these lesions is increasingly being performed as a less-invasive alternative to surgery. 1 Bohnacker S. Soehendra N. Maguchi H. et al. Endoscopic resection of benign tumors of the papilla of Vater. Endoscopy. 2006; 38: 521-525 Crossref PubMed Scopus (58) Google Scholar , 2 Yoon S.M. Kim M.H. Kim M.J. et al. Focal early stage cancer in ampullary adenoma: surgery or endoscopic papillectomy?. Gastrointest Endosc. 2007; 66: 701-707 Abstract Full Text Full Text PDF PubMed Scopus (97) Google Scholar , 3 Boix J. Lorenzo-Zúñiga V. Moreno de Vega V. et al. Endoscopic resection of ampullary tumors: 12-year review of 21 cases. Surg Endosc. 2009; 23: 45-49 Crossref PubMed Scopus (59) Google Scholar Complete histologic assessment of the resected specimen is desired to ensure curability with endoscopic therapy, because lesions may harbor focal invasive cancer missed on biopsy. However, en bloc resection that provides a complete tissue sample for pathologic evaluation is difficult for lesions larger than 2 cm with use of endoscopic snare ampullectomy. 4 Adler D.G. Qureshi W. Davila R. et al. The role of endoscopy in ampullary and duodenal adenomas. Gastrointest Endosc. 2006; 64: 849-854 Abstract Full Text Full Text PDF PubMed Scopus (134) Google Scholar , 5 Han J. Kim M.H. Endoscopic papillectomy for adenomas of the major duodenal papilla (with video). Gastrointest Endosc. 2006; 63: 292-301 Abstract Full Text Full Text PDF PubMed Scopus (91) Google Scholar Endoscopic submucosal dissection (ESD) is a recently developed technique that enables reliable en bloc resection of early stage GI neoplasms. 6 Yamamoto H. Technology insight: endoscopic submucosal dissection of gastrointestinal neoplasms. Nat Clin Pract Gastroenterol Hepatol. 2007; 4: 511-520 Crossref PubMed Scopus (45) Google Scholar ESD for ampullary neoplasm has not yet been reported. We describe our experience with successful ESD for a large ampullary adenoma with focal carcinoma." @default.
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- W2049912387 date "2009-09-01" @default.
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- W2049912387 title "Complete en bloc resection of a large ampullary adenoma with a focal adenocarcinoma by using endoscopic submucosal dissection (with video)" @default.
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- W2049912387 doi "https://doi.org/10.1016/j.gie.2008.12.237" @default.
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