FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2049984265> ?p ?o ?g. }

• W2049984265 endingPage "928" @default.
• W2049984265 startingPage "921" @default.
• W2049984265 abstract "Vasogenic edema after oxidative injury has been accompanied by intracellular accumulation of serum proteins and nuclear damage. This study sought to determine whether serum protein accumulation, along with other markers of brain injury, was present after exposure to intracerebral hemolysate, an oxidant model of intracerebral hemorrhage (ICH). Saline (n = 24) or hemolysate (n = 30) was injected into the caudate-putamen of adult Sprague-Dawley rats. Compared with saline, hemolysate deposition was associated with intracellular accumulation of serum proteins as evidenced by Evans blue uptake in neurons and microglia at 4 and 24 hours. Intracellular Evans blue colocalized with DNA fragmentation detected by nick end-labeling and whose presence was confirmed by gel electrophoresis. Immunoblots of cytosolic fractions confirmed cytochrome c release. Immunostaining established colocalization of cytosolic cytochrome c and intracellular Evans blue at 4 hours. At 24 hours, cytosolic cytochrome c was evident in astrocytes surrounding Evans blue-positive cells. Immunoblot analysis and immunostaining revealed HSP70 induction at 24 hours in regions adjacent to intracellular serum accumulation. Neuronal accumulation of extravasated serum proteins in this model of ICH was associated with cytochrome c release, DNA fragmentation, and cell death. Stress protein induction in adjacent regions suggested that vasogenic edema might have exacerbated cellular dysfunction and cell death after ICH." @default.
• W2049984265 created "2016-06-24" @default.
• W2049984265 creator A5018278284 @default.
• W2049984265 creator A5020764620 @default.
• W2049984265 creator A5073936292 @default.
• W2049984265 date "2001-08-01" @default.
• W2049984265 modified "2023-10-16" @default.
• W2049984265 title "Neuronal, but Not Microglial, Accumulation of Extravasated Serum Proteins after Intracerebral Hemolysate Exposure is Accompanied by Cytochrome <i>c</i> Release and DNA Fragmentation" @default.
• W2049984265 cites W1662237934 @default.
• W2049984265 cites W1965098515 @default.
• W2049984265 cites W1969467371 @default.
• W2049984265 cites W1972509721 @default.
• W2049984265 cites W1977004767 @default.
• W2049984265 cites W1977420171 @default.
• W2049984265 cites W1993716821 @default.
• W2049984265 cites W1998620774 @default.
• W2049984265 cites W2019867783 @default.
• W2049984265 cites W2028531319 @default.
• W2049984265 cites W2041561671 @default.
• W2049984265 cites W2050638637 @default.
• W2049984265 cites W2056034889 @default.
• W2049984265 cites W2060916730 @default.
• W2049984265 cites W2064971512 @default.
• W2049984265 cites W2090686203 @default.
• W2049984265 cites W2104713798 @default.
• W2049984265 cites W2134682338 @default.
• W2049984265 cites W2148167927 @default.
• W2049984265 cites W2149967205 @default.
• W2049984265 cites W2151544350 @default.
• W2049984265 cites W2157999078 @default.
• W2049984265 cites W2164254780 @default.
• W2049984265 cites W2885751699 @default.
• W2049984265 cites W4322703187 @default.
• W2049984265 doi "https://doi.org/10.1097/00004647-200108000-00004" @default.
• W2049984265 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11487727" @default.
• W2049984265 hasPublicationYear "2001" @default.
• W2049984265 type Work @default.
• W2049984265 sameAs 2049984265 @default.
• W2049984265 citedByCount "32" @default.
• W2049984265 countsByYear W20499842652012 @default.
• W2049984265 countsByYear W20499842652013 @default.
• W2049984265 countsByYear W20499842652014 @default.
• W2049984265 countsByYear W20499842652015 @default.
• W2049984265 countsByYear W20499842652016 @default.
• W2049984265 countsByYear W20499842652017 @default.
• W2049984265 countsByYear W20499842652022 @default.
• W2049984265 crossrefType "journal-article" @default.
• W2049984265 hasAuthorship W2049984265A5018278284 @default.
• W2049984265 hasAuthorship W2049984265A5020764620 @default.
• W2049984265 hasAuthorship W2049984265A5073936292 @default.
• W2049984265 hasBestOaLocation W20499842651 @default.
• W2049984265 hasConcept C134018914 @default.
• W2049984265 hasConcept C142724271 @default.
• W2049984265 hasConcept C153911025 @default.
• W2049984265 hasConcept C181199279 @default.
• W2049984265 hasConcept C185592680 @default.
• W2049984265 hasConcept C190283241 @default.
• W2049984265 hasConcept C203014093 @default.
• W2049984265 hasConcept C204232928 @default.
• W2049984265 hasConcept C2777649898 @default.
• W2049984265 hasConcept C29311851 @default.
• W2049984265 hasConcept C31573885 @default.
• W2049984265 hasConcept C4224716 @default.
• W2049984265 hasConcept C43759708 @default.
• W2049984265 hasConcept C55493867 @default.
• W2049984265 hasConcept C71924100 @default.
• W2049984265 hasConcept C79879829 @default.
• W2049984265 hasConcept C86803240 @default.
• W2049984265 hasConcept C98539663 @default.
• W2049984265 hasConceptScore W2049984265C134018914 @default.
• W2049984265 hasConceptScore W2049984265C142724271 @default.
• W2049984265 hasConceptScore W2049984265C153911025 @default.
• W2049984265 hasConceptScore W2049984265C181199279 @default.
• W2049984265 hasConceptScore W2049984265C185592680 @default.
• W2049984265 hasConceptScore W2049984265C190283241 @default.
• W2049984265 hasConceptScore W2049984265C203014093 @default.
• W2049984265 hasConceptScore W2049984265C204232928 @default.
• W2049984265 hasConceptScore W2049984265C2777649898 @default.
• W2049984265 hasConceptScore W2049984265C29311851 @default.
• W2049984265 hasConceptScore W2049984265C31573885 @default.
• W2049984265 hasConceptScore W2049984265C4224716 @default.
• W2049984265 hasConceptScore W2049984265C43759708 @default.
• W2049984265 hasConceptScore W2049984265C55493867 @default.
• W2049984265 hasConceptScore W2049984265C71924100 @default.
• W2049984265 hasConceptScore W2049984265C79879829 @default.
• W2049984265 hasConceptScore W2049984265C86803240 @default.
• W2049984265 hasConceptScore W2049984265C98539663 @default.
• W2049984265 hasIssue "8" @default.
• W2049984265 hasLocation W20499842651 @default.
• W2049984265 hasLocation W20499842652 @default.
• W2049984265 hasOpenAccess W2049984265 @default.
• W2049984265 hasPrimaryLocation W20499842651 @default.
• W2049984265 hasRelatedWork W1508359064 @default.
• W2049984265 hasRelatedWork W1570628773 @default.
• W2049984265 hasRelatedWork W1605282674 @default.
• W2049984265 hasRelatedWork W2065323371 @default.
• W2049984265 hasRelatedWork W2091518560 @default.
• W2049984265 hasRelatedWork W2100410073 @default.

• next