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- W2049994853 abstract "The transforming growth factor-beta (TGFbeta) family of growth factors are major regulators of wound repair, scar formation, and fibrosis. One of the prominent features of TGFbeta biology is the fact that this growth factor is secreted as a latent precursor, which may be directed to and stored at specific sites in the cellular microenvironment. Targeting and mobilization, and particularly extracellular activation of latent TGF-beta control the biological action of this growth factor. This review will focus on mechanisms of extracellular TGF-beta regulation relevant to and potentially operating in wound repair and scarring." @default.
- W2049994853 created "2016-06-24" @default.
- W2049994853 creator A5068934963 @default.
- W2049994853 creator A5082249674 @default.
- W2049994853 date "2004-01-01" @default.
- W2049994853 modified "2023-10-17" @default.
- W2049994853 title "Extracellular regulation of TGF-β activity in wound repair: growth factor latency as a sensor mechanism for injury" @default.
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- W2049994853 doi "https://doi.org/10.1160/th04-05-0324" @default.
- W2049994853 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15269820" @default.
- W2049994853 hasPublicationYear "2004" @default.
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