Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050085051> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2050085051 endingPage "59" @default.
- W2050085051 startingPage "52" @default.
- W2050085051 abstract "The distribution, retention, and fate of 2[3H]aminoanthracene (2-AA) were determined in male Fischer-344 rats after inhalation exposure (70 μg/liter; activity mass median diameter = 2.1 μm) for 30 min. Radioactivity was found in the turbinates, trachea, lungs, liver, kidneys, and gastrointestinal tract 20 min after exposure. Lower quantities of radioactivity were found in fat, brain, testes, and muscle. Inhaled 2-AA was excreted predominantly in feces (80%). The remaining 2-AA was excreted in urine. Organic soluble radioactivity was released from urinary conjugates after treatment of urine with acid and with β-glucuronidase. This result suggests that glucuronides of both ring- and N-hydroxy-2-AA were excreted. The remaining radioactivity was water soluble and accounted for approximately one-half of the total urinary radioactivity. The organic soluble radioactivity found after hydrolysis indicated that inhaled 2-AA is extensively metabolized by rats after inhalation and excreted as conjugated metabolites. Eighty-three percent or orally administered material was absorbed into the body from the GI tract; thus, material cleared by mucociliary action after inhalation would contribute to total body burden. 2-AA, a nitrogen substituted polycyclic aromatic hydrocarbon (PAH), was very similar to other PAHs in its rapid distribution throughout the body and in its route of excretion after inhalation." @default.
- W2050085051 created "2016-06-24" @default.
- W2050085051 creator A5022235434 @default.
- W2050085051 creator A5060068632 @default.
- W2050085051 creator A5076986859 @default.
- W2050085051 date "1984-08-01" @default.
- W2050085051 modified "2023-09-27" @default.
- W2050085051 title "Distribution, retention, and fate of 2-aminoanthracene in rats after inhalation" @default.
- W2050085051 cites W131571754 @default.
- W2050085051 cites W1520326862 @default.
- W2050085051 cites W1756164325 @default.
- W2050085051 cites W177448602 @default.
- W2050085051 cites W1815767349 @default.
- W2050085051 cites W1975605082 @default.
- W2050085051 cites W1976917904 @default.
- W2050085051 cites W1983948671 @default.
- W2050085051 cites W1992127522 @default.
- W2050085051 cites W2000749218 @default.
- W2050085051 cites W2004767774 @default.
- W2050085051 cites W2041037355 @default.
- W2050085051 cites W2041836753 @default.
- W2050085051 cites W2056964921 @default.
- W2050085051 cites W2077848541 @default.
- W2050085051 cites W2132760289 @default.
- W2050085051 cites W2159566963 @default.
- W2050085051 cites W2222749545 @default.
- W2050085051 cites W2283438955 @default.
- W2050085051 cites W2408868495 @default.
- W2050085051 cites W30734005 @default.
- W2050085051 cites W37942701 @default.
- W2050085051 cites W60306087 @default.
- W2050085051 cites W85636343 @default.
- W2050085051 cites W1996456355 @default.
- W2050085051 doi "https://doi.org/10.1016/0041-008x(84)90075-9" @default.
- W2050085051 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6464022" @default.
- W2050085051 hasPublicationYear "1984" @default.
- W2050085051 type Work @default.
- W2050085051 sameAs 2050085051 @default.
- W2050085051 citedByCount "9" @default.
- W2050085051 countsByYear W20500850512020 @default.
- W2050085051 crossrefType "journal-article" @default.
- W2050085051 hasAuthorship W2050085051A5022235434 @default.
- W2050085051 hasAuthorship W2050085051A5060068632 @default.
- W2050085051 hasAuthorship W2050085051A5076986859 @default.
- W2050085051 hasConcept C10146269 @default.
- W2050085051 hasConcept C134018914 @default.
- W2050085051 hasConcept C151730666 @default.
- W2050085051 hasConcept C185592680 @default.
- W2050085051 hasConcept C195289149 @default.
- W2050085051 hasConcept C2776954882 @default.
- W2050085051 hasConcept C2779777708 @default.
- W2050085051 hasConcept C2780026642 @default.
- W2050085051 hasConcept C2780512811 @default.
- W2050085051 hasConcept C42219234 @default.
- W2050085051 hasConcept C55493867 @default.
- W2050085051 hasConcept C61716771 @default.
- W2050085051 hasConcept C62231903 @default.
- W2050085051 hasConcept C71924100 @default.
- W2050085051 hasConcept C77411442 @default.
- W2050085051 hasConcept C86803240 @default.
- W2050085051 hasConcept C98274493 @default.
- W2050085051 hasConceptScore W2050085051C10146269 @default.
- W2050085051 hasConceptScore W2050085051C134018914 @default.
- W2050085051 hasConceptScore W2050085051C151730666 @default.
- W2050085051 hasConceptScore W2050085051C185592680 @default.
- W2050085051 hasConceptScore W2050085051C195289149 @default.
- W2050085051 hasConceptScore W2050085051C2776954882 @default.
- W2050085051 hasConceptScore W2050085051C2779777708 @default.
- W2050085051 hasConceptScore W2050085051C2780026642 @default.
- W2050085051 hasConceptScore W2050085051C2780512811 @default.
- W2050085051 hasConceptScore W2050085051C42219234 @default.
- W2050085051 hasConceptScore W2050085051C55493867 @default.
- W2050085051 hasConceptScore W2050085051C61716771 @default.
- W2050085051 hasConceptScore W2050085051C62231903 @default.
- W2050085051 hasConceptScore W2050085051C71924100 @default.
- W2050085051 hasConceptScore W2050085051C77411442 @default.
- W2050085051 hasConceptScore W2050085051C86803240 @default.
- W2050085051 hasConceptScore W2050085051C98274493 @default.
- W2050085051 hasIssue "1" @default.
- W2050085051 hasLocation W20500850511 @default.
- W2050085051 hasLocation W20500850512 @default.
- W2050085051 hasOpenAccess W2050085051 @default.
- W2050085051 hasPrimaryLocation W20500850511 @default.
- W2050085051 hasRelatedWork W1964074988 @default.
- W2050085051 hasRelatedWork W2014626913 @default.
- W2050085051 hasRelatedWork W2039907201 @default.
- W2050085051 hasRelatedWork W2042767146 @default.
- W2050085051 hasRelatedWork W2047666596 @default.
- W2050085051 hasRelatedWork W2321035358 @default.
- W2050085051 hasRelatedWork W2409885688 @default.
- W2050085051 hasRelatedWork W2903773567 @default.
- W2050085051 hasRelatedWork W40521540 @default.
- W2050085051 hasRelatedWork W4301113754 @default.
- W2050085051 hasVolume "75" @default.
- W2050085051 isParatext "false" @default.
- W2050085051 isRetracted "false" @default.
- W2050085051 magId "2050085051" @default.
- W2050085051 workType "article" @default.