Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050108945> ?p ?o ?g. }
Showing items 1 to 83 of
83
with 100 items per page.
- W2050108945 endingPage "362" @default.
- W2050108945 startingPage "357" @default.
- W2050108945 abstract "Abstract: Biliary obstruction has been recognized to inhibit excretion of antibiotics into bile. In the present study, using cefpirome sulfate (CPR), we sought to determine the effect of biliary pressure on antibiotic transfer into bile in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP). Thirty‐six patients with a variety of biliopancreatic diseases (free of renal disease or hypoproteinemia) received a single intravenous dose of CPR (1 g) prior to ERCP. Under fluoroscopy a diagnostic catheter with a metal ball tip was advanced into the middle portion of the extrahepatic bile duct or, in cases of common bile duct obstruction, above the obstruction. Biliary pressure was measured via the same catheter using duodenal pressure as a reference. Subsequently, bile was aspirated, and blood was withdrawn simultaneously. The mean interval between CPR administration and the bile and blood samplings was 67±12 minutes. The bile CPR concentration and the bile/serum ratio of CPR concentrations showed a significant inverse correlation with biliary pressure, but the serum CPR concentration did not. The bile CPR concentration and the bile/serum ratio of CPR concentrations differed significantly between the group with normal biliary pressures, below 10 mmHg, and that with biliary pressures exceeding 10 mmHg. The serum CPR concentrations of the two groups were similar. These results suggest that biliary pressure plays an important role in determining antibiotic transfer into bile." @default.
- W2050108945 created "2016-06-24" @default.
- W2050108945 creator A5007749422 @default.
- W2050108945 creator A5015053570 @default.
- W2050108945 creator A5017832747 @default.
- W2050108945 creator A5043129771 @default.
- W2050108945 creator A5064633592 @default.
- W2050108945 creator A5065489944 @default.
- W2050108945 creator A5067418325 @default.
- W2050108945 creator A5071231555 @default.
- W2050108945 creator A5087940387 @default.
- W2050108945 date "1995-10-01" @default.
- W2050108945 modified "2023-09-27" @default.
- W2050108945 title "The Effect of Biliary Pressure on Antibiotic Excretion into Bile" @default.
- W2050108945 cites W1516998764 @default.
- W2050108945 cites W1966045807 @default.
- W2050108945 cites W1967771517 @default.
- W2050108945 cites W1984392775 @default.
- W2050108945 cites W2003147749 @default.
- W2050108945 cites W2011659457 @default.
- W2050108945 cites W2068956726 @default.
- W2050108945 cites W2084764679 @default.
- W2050108945 cites W2090166407 @default.
- W2050108945 cites W2093772999 @default.
- W2050108945 cites W2114319505 @default.
- W2050108945 cites W2158612332 @default.
- W2050108945 doi "https://doi.org/10.1111/j.1443-1661.1995.tb00388.x" @default.
- W2050108945 hasPublicationYear "1995" @default.
- W2050108945 type Work @default.
- W2050108945 sameAs 2050108945 @default.
- W2050108945 citedByCount "2" @default.
- W2050108945 countsByYear W20501089452019 @default.
- W2050108945 crossrefType "journal-article" @default.
- W2050108945 hasAuthorship W2050108945A5007749422 @default.
- W2050108945 hasAuthorship W2050108945A5015053570 @default.
- W2050108945 hasAuthorship W2050108945A5017832747 @default.
- W2050108945 hasAuthorship W2050108945A5043129771 @default.
- W2050108945 hasAuthorship W2050108945A5064633592 @default.
- W2050108945 hasAuthorship W2050108945A5065489944 @default.
- W2050108945 hasAuthorship W2050108945A5067418325 @default.
- W2050108945 hasAuthorship W2050108945A5071231555 @default.
- W2050108945 hasAuthorship W2050108945A5087940387 @default.
- W2050108945 hasConcept C126322002 @default.
- W2050108945 hasConcept C141071460 @default.
- W2050108945 hasConcept C2775967933 @default.
- W2050108945 hasConcept C2775982439 @default.
- W2050108945 hasConcept C2776884468 @default.
- W2050108945 hasConcept C2778444009 @default.
- W2050108945 hasConcept C2779777945 @default.
- W2050108945 hasConcept C2781267111 @default.
- W2050108945 hasConcept C71924100 @default.
- W2050108945 hasConcept C90924648 @default.
- W2050108945 hasConceptScore W2050108945C126322002 @default.
- W2050108945 hasConceptScore W2050108945C141071460 @default.
- W2050108945 hasConceptScore W2050108945C2775967933 @default.
- W2050108945 hasConceptScore W2050108945C2775982439 @default.
- W2050108945 hasConceptScore W2050108945C2776884468 @default.
- W2050108945 hasConceptScore W2050108945C2778444009 @default.
- W2050108945 hasConceptScore W2050108945C2779777945 @default.
- W2050108945 hasConceptScore W2050108945C2781267111 @default.
- W2050108945 hasConceptScore W2050108945C71924100 @default.
- W2050108945 hasConceptScore W2050108945C90924648 @default.
- W2050108945 hasIssue "4" @default.
- W2050108945 hasLocation W20501089451 @default.
- W2050108945 hasOpenAccess W2050108945 @default.
- W2050108945 hasPrimaryLocation W20501089451 @default.
- W2050108945 hasRelatedWork W1984618456 @default.
- W2050108945 hasRelatedWork W2464996402 @default.
- W2050108945 hasRelatedWork W2588908710 @default.
- W2050108945 hasRelatedWork W2800245977 @default.
- W2050108945 hasRelatedWork W3028777471 @default.
- W2050108945 hasRelatedWork W3029322827 @default.
- W2050108945 hasRelatedWork W3042873504 @default.
- W2050108945 hasRelatedWork W3119560125 @default.
- W2050108945 hasRelatedWork W3127402906 @default.
- W2050108945 hasRelatedWork W4313127081 @default.
- W2050108945 hasVolume "7" @default.
- W2050108945 isParatext "false" @default.
- W2050108945 isRetracted "false" @default.
- W2050108945 magId "2050108945" @default.
- W2050108945 workType "article" @default.