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- W205013009 abstract "Ghrelin is a novel growth hormone-releasing peptide that also causes a positive energy balance by stimulating food intake and inducing adiposity through growth hormone (GH)-independent mechanisms. Ghrelin has some cardiovascular effects, including vasodilation, as indicated by the presence of its receptor in blood vessels and the cardiac ventricles. Ghrelin also inhibits cell apoptosis and sympathetic nerve activities. Short-term infusion of ghrelin decreases systemic vascular resistance and increases cardiac output in patients with heart failure. Repeated administration of ghrelin improves cardiac structure and function and attenuates the development of cardiac cachexia. These results suggest that ghrelin has cardiovascular effects and regulates energy metabolism through GH-dependent and -independent mechanisms." @default.
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- W205013009 date "2006-01-01" @default.
- W205013009 modified "2023-09-25" @default.
- W205013009 title "Ghrelin: Its Therapeutic Potential in Heart Failure" @default.
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- W205013009 doi "https://doi.org/10.1016/b978-012369442-3/50167-7" @default.
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