Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050154310> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2050154310 endingPage "2232" @default.
- W2050154310 startingPage "2225" @default.
- W2050154310 abstract "Advances in molecular biology have contributed to a growing interest in gene therapy as a form of management for neurologic diseases. However, implementation requires knowledge of the regulatory policies governing this field of research, especially in view of the greater stringency imposed by the serious adverse events affecting some patients participating in gene therapy protocols. Educational resources for neurologists, or any clinicians, who hope to serve as potential principal investigators for a gene therapy protocol are not available through any single source, requiring considerable effort to discover appropriate guidance. Summarized here are the regulatory agencies and their requirements, the phases of clinical development with emphasis on a Phase I study, and specific steps leading to an Investigational New Drug application for a biologic product to be used in a gene therapy clinical trial. The links provided to all appropriate Web sites will facilitate the process for the clinician investigator." @default.
- W2050154310 created "2016-06-24" @default.
- W2050154310 creator A5009095280 @default.
- W2050154310 creator A5047809221 @default.
- W2050154310 date "2004-12-28" @default.
- W2050154310 modified "2023-09-25" @default.
- W2050154310 title "Gene transfer for neurologic disease" @default.
- W2050154310 cites W1967098175 @default.
- W2050154310 cites W1972514500 @default.
- W2050154310 cites W1977142869 @default.
- W2050154310 cites W1994566132 @default.
- W2050154310 cites W2002104055 @default.
- W2050154310 cites W2022790215 @default.
- W2050154310 cites W2025728946 @default.
- W2050154310 cites W2031373782 @default.
- W2050154310 cites W2032097547 @default.
- W2050154310 cites W2044005085 @default.
- W2050154310 cites W2066621874 @default.
- W2050154310 cites W2089134063 @default.
- W2050154310 cites W2098079634 @default.
- W2050154310 cites W2119164964 @default.
- W2050154310 cites W2121683076 @default.
- W2050154310 cites W2128439024 @default.
- W2050154310 cites W2130547944 @default.
- W2050154310 cites W2137440275 @default.
- W2050154310 cites W2139865704 @default.
- W2050154310 cites W2157571916 @default.
- W2050154310 doi "https://doi.org/10.1212/01.wnl.0000147331.17276.f9" @default.
- W2050154310 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15623678" @default.
- W2050154310 hasPublicationYear "2004" @default.
- W2050154310 type Work @default.
- W2050154310 sameAs 2050154310 @default.
- W2050154310 citedByCount "4" @default.
- W2050154310 countsByYear W20501543102013 @default.
- W2050154310 countsByYear W20501543102019 @default.
- W2050154310 crossrefType "journal-article" @default.
- W2050154310 hasAuthorship W2050154310A5009095280 @default.
- W2050154310 hasAuthorship W2050154310A5047809221 @default.
- W2050154310 hasConcept C104317684 @default.
- W2050154310 hasConcept C111599444 @default.
- W2050154310 hasConcept C111919701 @default.
- W2050154310 hasConcept C142724271 @default.
- W2050154310 hasConcept C144559511 @default.
- W2050154310 hasConcept C177713679 @default.
- W2050154310 hasConcept C204787440 @default.
- W2050154310 hasConcept C2779134260 @default.
- W2050154310 hasConcept C2780385302 @default.
- W2050154310 hasConcept C3018928802 @default.
- W2050154310 hasConcept C41008148 @default.
- W2050154310 hasConcept C535046627 @default.
- W2050154310 hasConcept C54355233 @default.
- W2050154310 hasConcept C60644358 @default.
- W2050154310 hasConcept C71924100 @default.
- W2050154310 hasConcept C86803240 @default.
- W2050154310 hasConceptScore W2050154310C104317684 @default.
- W2050154310 hasConceptScore W2050154310C111599444 @default.
- W2050154310 hasConceptScore W2050154310C111919701 @default.
- W2050154310 hasConceptScore W2050154310C142724271 @default.
- W2050154310 hasConceptScore W2050154310C144559511 @default.
- W2050154310 hasConceptScore W2050154310C177713679 @default.
- W2050154310 hasConceptScore W2050154310C204787440 @default.
- W2050154310 hasConceptScore W2050154310C2779134260 @default.
- W2050154310 hasConceptScore W2050154310C2780385302 @default.
- W2050154310 hasConceptScore W2050154310C3018928802 @default.
- W2050154310 hasConceptScore W2050154310C41008148 @default.
- W2050154310 hasConceptScore W2050154310C535046627 @default.
- W2050154310 hasConceptScore W2050154310C54355233 @default.
- W2050154310 hasConceptScore W2050154310C60644358 @default.
- W2050154310 hasConceptScore W2050154310C71924100 @default.
- W2050154310 hasConceptScore W2050154310C86803240 @default.
- W2050154310 hasIssue "12" @default.
- W2050154310 hasLocation W20501543101 @default.
- W2050154310 hasLocation W20501543102 @default.
- W2050154310 hasOpenAccess W2050154310 @default.
- W2050154310 hasPrimaryLocation W20501543101 @default.
- W2050154310 hasRelatedWork W1964222219 @default.
- W2050154310 hasRelatedWork W1993780631 @default.
- W2050154310 hasRelatedWork W2010168053 @default.
- W2050154310 hasRelatedWork W2039790484 @default.
- W2050154310 hasRelatedWork W2044532250 @default.
- W2050154310 hasRelatedWork W2058040891 @default.
- W2050154310 hasRelatedWork W2129583958 @default.
- W2050154310 hasRelatedWork W2157571916 @default.
- W2050154310 hasRelatedWork W2227052658 @default.
- W2050154310 hasRelatedWork W3134077053 @default.
- W2050154310 hasVolume "63" @default.
- W2050154310 isParatext "false" @default.
- W2050154310 isRetracted "false" @default.
- W2050154310 magId "2050154310" @default.
- W2050154310 workType "article" @default.