Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050170820> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W2050170820 endingPage "98" @default.
- W2050170820 startingPage "92" @default.
- W2050170820 abstract "To describe prolongation of survival in patients with amyotrophic lateral sclerosis (ALS) by continuous noninvasive intermittent positive-pressure ventilation (NPPV) and mechanically assisted coughing (MAC) using oximetry as feedback.A retrospective review of ALS patients visiting one center from 1990 to 2000.Patients were trained in mouthpiece and nasal NPPV when symptomatic for hypoventilation, and trained in MAC with oximetry feedback when assisted peak cough flow (PCF) levels decreased to < 270 L/min. Survival was considered to be prolonged when full-time NPPV was required with limited ventilator-free breathing tolerance.Of 101 patients who met the criteria for access to NPPV and MAC, 15 have not yet used them, and 11 patients with severe bulbar muscle dysfunction died without ever successfully using them. Three patients used NPPV full-time, and oximetry and MAC episodically, but did not yet require ongoing NPPV. Eighteen used NPPV part-time for a mean (+/- SD) duration of 3.8 +/- 4.1 months. Nineteen others underwent tracheotomy after 4.7 +/- 4.5 months of receiving part-time NPPV. Sixteen patients used part-time NPPV for 17.5 +/- 13.0 months (maximum, 25 months), then full-time NPPV for 14.1 +/- 12.6 months (maximum, 40 months) before undergoing tracheotomy. Nineteen patients used part-time and full-time NPPV for 25.2 +/- 19.8 months (maximum, 114 months) and 17.5 +/- 13.3 months (maximum, 87 months), respectively, without undergoing tracheotomy. Ten of these NPPV users died once bulbar dysfunction became severe.We conclude that up to continuous use of NPPV, along with MAC when needed, can permit prolonged survival and delay the need for tracheotomy for a significant minority of ALS patients by > 1 year." @default.
- W2050170820 created "2016-06-24" @default.
- W2050170820 creator A5025636320 @default.
- W2050170820 date "2002-07-01" @default.
- W2050170820 modified "2023-09-30" @default.
- W2050170820 title "Amyotrophic Lateral Sclerosis" @default.
- W2050170820 cites W1976995645 @default.
- W2050170820 cites W1988083266 @default.
- W2050170820 cites W2005463343 @default.
- W2050170820 cites W2041010446 @default.
- W2050170820 cites W2045792974 @default.
- W2050170820 cites W2046177286 @default.
- W2050170820 cites W2057769638 @default.
- W2050170820 cites W2057876524 @default.
- W2050170820 cites W2070796603 @default.
- W2050170820 cites W2073818203 @default.
- W2050170820 cites W2086382526 @default.
- W2050170820 cites W2095861983 @default.
- W2050170820 cites W2123356698 @default.
- W2050170820 cites W2125673224 @default.
- W2050170820 cites W2140860447 @default.
- W2050170820 cites W2161128210 @default.
- W2050170820 cites W2162556081 @default.
- W2050170820 cites W2166621696 @default.
- W2050170820 cites W2172088148 @default.
- W2050170820 cites W2317061064 @default.
- W2050170820 cites W2329899462 @default.
- W2050170820 cites W2408533937 @default.
- W2050170820 cites W2782018707 @default.
- W2050170820 cites W38677234 @default.
- W2050170820 doi "https://doi.org/10.1378/chest.122.1.92" @default.
- W2050170820 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12114343" @default.
- W2050170820 hasPublicationYear "2002" @default.
- W2050170820 type Work @default.
- W2050170820 sameAs 2050170820 @default.
- W2050170820 citedByCount "250" @default.
- W2050170820 countsByYear W20501708202012 @default.
- W2050170820 countsByYear W20501708202013 @default.
- W2050170820 countsByYear W20501708202014 @default.
- W2050170820 countsByYear W20501708202015 @default.
- W2050170820 countsByYear W20501708202016 @default.
- W2050170820 countsByYear W20501708202017 @default.
- W2050170820 countsByYear W20501708202018 @default.
- W2050170820 countsByYear W20501708202019 @default.
- W2050170820 countsByYear W20501708202020 @default.
- W2050170820 countsByYear W20501708202021 @default.
- W2050170820 countsByYear W20501708202022 @default.
- W2050170820 countsByYear W20501708202023 @default.
- W2050170820 crossrefType "journal-article" @default.
- W2050170820 hasAuthorship W2050170820A5025636320 @default.
- W2050170820 hasConcept C126322002 @default.
- W2050170820 hasConcept C199343813 @default.
- W2050170820 hasConcept C2778551211 @default.
- W2050170820 hasConcept C2779134260 @default.
- W2050170820 hasConcept C2779594553 @default.
- W2050170820 hasConcept C2780596555 @default.
- W2050170820 hasConcept C2780955776 @default.
- W2050170820 hasConcept C42219234 @default.
- W2050170820 hasConcept C534529494 @default.
- W2050170820 hasConcept C71924100 @default.
- W2050170820 hasConceptScore W2050170820C126322002 @default.
- W2050170820 hasConceptScore W2050170820C199343813 @default.
- W2050170820 hasConceptScore W2050170820C2778551211 @default.
- W2050170820 hasConceptScore W2050170820C2779134260 @default.
- W2050170820 hasConceptScore W2050170820C2779594553 @default.
- W2050170820 hasConceptScore W2050170820C2780596555 @default.
- W2050170820 hasConceptScore W2050170820C2780955776 @default.
- W2050170820 hasConceptScore W2050170820C42219234 @default.
- W2050170820 hasConceptScore W2050170820C534529494 @default.
- W2050170820 hasConceptScore W2050170820C71924100 @default.
- W2050170820 hasIssue "1" @default.
- W2050170820 hasLocation W20501708201 @default.
- W2050170820 hasLocation W20501708202 @default.
- W2050170820 hasOpenAccess W2050170820 @default.
- W2050170820 hasPrimaryLocation W20501708201 @default.
- W2050170820 hasRelatedWork W1827942089 @default.
- W2050170820 hasRelatedWork W2050170820 @default.
- W2050170820 hasRelatedWork W2059677616 @default.
- W2050170820 hasRelatedWork W2238433182 @default.
- W2050170820 hasRelatedWork W2317610620 @default.
- W2050170820 hasRelatedWork W2593352311 @default.
- W2050170820 hasRelatedWork W2594689658 @default.
- W2050170820 hasRelatedWork W3015866742 @default.
- W2050170820 hasRelatedWork W3108779083 @default.
- W2050170820 hasRelatedWork W3160187235 @default.
- W2050170820 hasVolume "122" @default.
- W2050170820 isParatext "false" @default.
- W2050170820 isRetracted "false" @default.
- W2050170820 magId "2050170820" @default.
- W2050170820 workType "article" @default.