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- W2050200116 abstract "A short and efficient total synthesis of racemic AT-125 and its racemic threo isomer proceeds via an intramolecular Michael cyclization of a protected α,β-dehydroglutamic acid γ-hydroxamate. Separation of diastereomers and deprotection to racemic AT-125 followed by enzymatic resolution of the N-chloroacetamide with hog-kidney acylase provides the natural αS,5S isomer." @default.
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- W2050200116 title "Total synthesis of antitumor agent at-125, (αS,5S)-α-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid" @default.
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