FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050236889> ?p ?o ?g. }

• W2050236889 endingPage "9035" @default.
• W2050236889 startingPage "9029" @default.
• W2050236889 abstract "Proteasome-containing bacteria possess a tagging system that directs proteins to proteasomal degradation by conjugating them to a prokaryotic ubiquitin-like protein (Pup). A single ligating enzyme, PafA, is responsible for Pup conjugation to lysine side chains of protein substrates. As Pup is recognized by the regulatory subunit of the proteasome, Pup functions as a degradation tag. Pup presents overlapping regions for binding of the proteasome and PafA. It was, therefore, unclear whether Pup binding by the proteasome regulatory subunit, Mpa, and by PafA are mutually exclusive events. The work presented here provides evidence for the simultaneous interaction of Pup with both Mpa and PafA. Surprisingly, we found that PafA and Mpa can form a complex both in vitro and in vivo. Our results thus suggest that PafA and the proteasome can function as a modular machine for the tagging and degradation of cytoplasmic proteins." @default.
• W2050236889 created "2016-06-24" @default.
• W2050236889 creator A5013945501 @default.
• W2050236889 creator A5016269061 @default.
• W2050236889 creator A5049928591 @default.
• W2050236889 creator A5083696070 @default.
• W2050236889 creator A5090391827 @default.
• W2050236889 date "2013-11-20" @default.
• W2050236889 modified "2023-09-24" @default.
• W2050236889 title "Bacterial Proteasome and PafA, the Pup Ligase, Interact to Form a Modular Protein Tagging and Degradation Machine" @default.
• W2050236889 cites W1604716826 @default.
• W2050236889 cites W1963940469 @default.
• W2050236889 cites W1966068873 @default.
• W2050236889 cites W1969090679 @default.
• W2050236889 cites W1975173458 @default.
• W2050236889 cites W1994526268 @default.
• W2050236889 cites W1994676170 @default.
• W2050236889 cites W1996520342 @default.
• W2050236889 cites W1999119754 @default.
• W2050236889 cites W2005756027 @default.
• W2050236889 cites W2008653827 @default.
• W2050236889 cites W2027971820 @default.
• W2050236889 cites W2035310578 @default.
• W2050236889 cites W2044163830 @default.
• W2050236889 cites W2062306301 @default.
• W2050236889 cites W2066476512 @default.
• W2050236889 cites W2066813187 @default.
• W2050236889 cites W2080063823 @default.
• W2050236889 cites W2081444617 @default.
• W2050236889 cites W2081929782 @default.
• W2050236889 cites W2082837078 @default.
• W2050236889 cites W2091214708 @default.
• W2050236889 cites W2107272621 @default.
• W2050236889 cites W2123692607 @default.
• W2050236889 cites W2156285140 @default.
• W2050236889 cites W2159586303 @default.
• W2050236889 cites W2169024001 @default.
• W2050236889 cites W2171814990 @default.
• W2050236889 cites W2213968760 @default.
• W2050236889 cites W2313781852 @default.
• W2050236889 cites W69814808 @default.
• W2050236889 doi "https://doi.org/10.1021/bi401017b" @default.
• W2050236889 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24228735" @default.
• W2050236889 hasPublicationYear "2013" @default.
• W2050236889 type Work @default.
• W2050236889 sameAs 2050236889 @default.
• W2050236889 citedByCount "13" @default.
• W2050236889 countsByYear W20502368892014 @default.
• W2050236889 countsByYear W20502368892015 @default.
• W2050236889 countsByYear W20502368892016 @default.
• W2050236889 countsByYear W20502368892017 @default.
• W2050236889 countsByYear W20502368892019 @default.
• W2050236889 countsByYear W20502368892020 @default.
• W2050236889 countsByYear W20502368892021 @default.
• W2050236889 crossrefType "journal-article" @default.
• W2050236889 hasAuthorship W2050236889A5013945501 @default.
• W2050236889 hasAuthorship W2050236889A5016269061 @default.
• W2050236889 hasAuthorship W2050236889A5049928591 @default.
• W2050236889 hasAuthorship W2050236889A5083696070 @default.
• W2050236889 hasAuthorship W2050236889A5090391827 @default.
• W2050236889 hasConcept C104292427 @default.
• W2050236889 hasConcept C104317684 @default.
• W2050236889 hasConcept C175114707 @default.
• W2050236889 hasConcept C181199279 @default.
• W2050236889 hasConcept C185592680 @default.
• W2050236889 hasConcept C25602115 @default.
• W2050236889 hasConcept C27740335 @default.
• W2050236889 hasConcept C2992195973 @default.
• W2050236889 hasConcept C55493867 @default.
• W2050236889 hasConcept C86803240 @default.
• W2050236889 hasConcept C95444343 @default.
• W2050236889 hasConceptScore W2050236889C104292427 @default.
• W2050236889 hasConceptScore W2050236889C104317684 @default.
• W2050236889 hasConceptScore W2050236889C175114707 @default.
• W2050236889 hasConceptScore W2050236889C181199279 @default.
• W2050236889 hasConceptScore W2050236889C185592680 @default.
• W2050236889 hasConceptScore W2050236889C25602115 @default.
• W2050236889 hasConceptScore W2050236889C27740335 @default.
• W2050236889 hasConceptScore W2050236889C2992195973 @default.
• W2050236889 hasConceptScore W2050236889C55493867 @default.
• W2050236889 hasConceptScore W2050236889C86803240 @default.
• W2050236889 hasConceptScore W2050236889C95444343 @default.
• W2050236889 hasIssue "50" @default.
• W2050236889 hasLocation W20502368891 @default.
• W2050236889 hasLocation W20502368892 @default.
• W2050236889 hasOpenAccess W2050236889 @default.
• W2050236889 hasPrimaryLocation W20502368891 @default.
• W2050236889 hasRelatedWork W2034839450 @default.
• W2050236889 hasRelatedWork W2038751264 @default.
• W2050236889 hasRelatedWork W2155612332 @default.
• W2050236889 hasRelatedWork W2197922884 @default.
• W2050236889 hasRelatedWork W2230621123 @default.
• W2050236889 hasRelatedWork W2364617462 @default.
• W2050236889 hasRelatedWork W2413271731 @default.
• W2050236889 hasRelatedWork W2892928169 @default.
• W2050236889 hasRelatedWork W2960530550 @default.
• W2050236889 hasRelatedWork W4214907302 @default.
• W2050236889 hasVolume "52" @default.

• next