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- W2050252010 abstract "Abstracto1.Juvenile Xenopus laevis can be easily adapted to 300 mOsm urea in the external medium, which makes it possible to study cell volume regulatory mechanisms induced by a penetrating external substance (high osmolality and low tonicity).2.Water loss was caused during the first days of adaptation.3.Despite urea entrance, urea was not equally distributed, the internal concentration reached only about 1/3 of the external.4.Increase of plasma osmolality above external level was observed due to an increase of Na+, Cl− and urea concentration.5.Decrease of Na content and increase of urea content of the cell resulted together with a decrease of intracellular space.6.Intracellular volume reduction was not regulated during the experimental period which clearly distinguishes this type of adaptation from adaptation to NaCl or impermeable mannitol. Juvenile Xenopus laevis can be easily adapted to 300 mOsm urea in the external medium, which makes it possible to study cell volume regulatory mechanisms induced by a penetrating external substance (high osmolality and low tonicity). Water loss was caused during the first days of adaptation. Despite urea entrance, urea was not equally distributed, the internal concentration reached only about 1/3 of the external. Increase of plasma osmolality above external level was observed due to an increase of Na+, Cl− and urea concentration. Decrease of Na content and increase of urea content of the cell resulted together with a decrease of intracellular space. Intracellular volume reduction was not regulated during the experimental period which clearly distinguishes this type of adaptation from adaptation to NaCl or impermeable mannitol." @default.
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- W2050252010 date "1980-01-01" @default.
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- W2050252010 title "Cell volume regulation in juveniles of xenopus laevis in hypertonic urea solution" @default.
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- W2050252010 doi "https://doi.org/10.1016/s0300-9629(80)80010-7" @default.
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