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- W2050254006 abstract "Epitopes for four monoclonal antibodies (mAbs) to the gamma subunit of Torpedo nicotinic acetylcholine receptor (AChR), and one mAb crossreactive with the gamma and delta subunits of Torpedo AChR were mapped using overlapping synthetic peptides corresponding to the complete amino acid sequence of Torpedo gamma subunit. The epitopes for all mAbs were within a 50 residue sequence region, on the cytoplasmic surface of the AChR. Three mAbs crossreacted with mammalian muscle AChRs. Two of them specifically recognized the epsilon subunit of AChRs at adult neuromuscular junction. The epsilon-specific mAbs were used, in conjunction with mAbs specific for the alpha and beta subunits and anti-peptide antisera specific for the epsilon, gamma and delta subunits, to identify in Western blots the subunit complement of embryonic and adult bovine muscle AChRs." @default.
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- W2050254006 date "1992-01-01" @default.
- W2050254006 modified "2023-10-16" @default.
- W2050254006 title "Epitope mapping of monoclonal antibodies to Torpedo acetylcholine receptor γ subunits, which specifically recognize the ϵ subunit of mammalian muscle acetylcholine receptor" @default.
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- W2050254006 doi "https://doi.org/10.1016/0165-5728(92)90027-i" @default.
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