FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050261148> ?p ?o ?g. }

• W2050261148 endingPage "2925" @default.
• W2050261148 startingPage "2916" @default.
• W2050261148 abstract "Biologic scaffolds prepared from the extracellular matrix (ECM) of decellularized mammalian tissues have been shown to facilitate constructive remodeling in injured tissues such as skeletal muscle, the esophagus, and lower urinary tract, among others. The ECM of every tissue has a unique composition and structure that likely has direct effects on the host response and it is plausible that ECM harvested from a given tissue would provide distinct advantages over ECM harvested from nonhomologous tissues. For example, a tissue specific muscle ECM scaffold may be more suitable for constructive remodeling of skeletal muscle than non-homologous ECM tissue sources. The present study describes an enzymatic and chemical decellularization process for isolating skeletal muscle ECM scaffolds using established decellularization criteria and characterized the structure and chemical composition of the resulting ECM. The results were compared to those from a non-muscle ECM derived from small intestine (SIS). Muscle ECM was shown to contain growth factors, glycosaminoglycans, and basement membrane structural proteins which differed from those present in SIS. Myogenic cells survived and proliferated on muscle ECM scaffolds in vitro, and when implanted in a rat abdominal wall injury model in vivo was shown to induce a constructive remodeling response associated with scaffold degradation and myogenesis in the implant area; however, the remodeling outcome did not differ from that induced by SIS by 35 days post surgery. These results suggest that superior tissue remodeling outcomes are not universally dependent upon homologous tissue derived ECM scaffold materials." @default.
• W2050261148 created "2016-06-24" @default.
• W2050261148 creator A5027253014 @default.
• W2050261148 creator A5040936050 @default.
• W2050261148 creator A5073097748 @default.
• W2050261148 creator A5074400934 @default.
• W2050261148 date "2012-04-01" @default.
• W2050261148 modified "2023-10-05" @default.
• W2050261148 title "Biologic scaffold composed of skeletal muscle extracellular matrix" @default.
• W2050261148 cites W1852354029 @default.
• W2050261148 cites W1876517475 @default.
• W2050261148 cites W1969390542 @default.
• W2050261148 cites W1970291858 @default.
• W2050261148 cites W1971189453 @default.
• W2050261148 cites W1974157838 @default.
• W2050261148 cites W1977447348 @default.
• W2050261148 cites W1977802438 @default.
• W2050261148 cites W1982270848 @default.
• W2050261148 cites W1984133400 @default.
• W2050261148 cites W1984820597 @default.
• W2050261148 cites W1985199900 @default.
• W2050261148 cites W1988393390 @default.
• W2050261148 cites W1988843437 @default.
• W2050261148 cites W1999298099 @default.
• W2050261148 cites W1999579326 @default.
• W2050261148 cites W2002230244 @default.
• W2050261148 cites W2003924286 @default.
• W2050261148 cites W2011590786 @default.
• W2050261148 cites W2018599317 @default.
• W2050261148 cites W2018654772 @default.
• W2050261148 cites W2024226604 @default.
• W2050261148 cites W2025922881 @default.
• W2050261148 cites W2031013234 @default.
• W2050261148 cites W2032856345 @default.
• W2050261148 cites W2033817116 @default.
• W2050261148 cites W2036279456 @default.
• W2050261148 cites W2041180426 @default.
• W2050261148 cites W2046537667 @default.
• W2050261148 cites W2056557833 @default.
• W2050261148 cites W2059486645 @default.
• W2050261148 cites W2066390688 @default.
• W2050261148 cites W2076491580 @default.
• W2050261148 cites W2078489764 @default.
• W2050261148 cites W2078741183 @default.
• W2050261148 cites W2078763854 @default.
• W2050261148 cites W2079165554 @default.
• W2050261148 cites W2084849128 @default.
• W2050261148 cites W2088883625 @default.
• W2050261148 cites W2094492677 @default.
• W2050261148 cites W2107291281 @default.
• W2050261148 cites W2111338636 @default.
• W2050261148 cites W2116397695 @default.
• W2050261148 cites W2139194628 @default.
• W2050261148 cites W2139388487 @default.
• W2050261148 cites W2151838922 @default.
• W2050261148 doi "https://doi.org/10.1016/j.biomaterials.2011.12.055" @default.
• W2050261148 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5942557" @default.
• W2050261148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22264525" @default.
• W2050261148 hasPublicationYear "2012" @default.
• W2050261148 type Work @default.
• W2050261148 sameAs 2050261148 @default.
• W2050261148 citedByCount "224" @default.
• W2050261148 countsByYear W20502611482012 @default.
• W2050261148 countsByYear W20502611482013 @default.
• W2050261148 countsByYear W20502611482014 @default.
• W2050261148 countsByYear W20502611482015 @default.
• W2050261148 countsByYear W20502611482016 @default.
• W2050261148 countsByYear W20502611482017 @default.
• W2050261148 countsByYear W20502611482018 @default.
• W2050261148 countsByYear W20502611482019 @default.
• W2050261148 countsByYear W20502611482020 @default.
• W2050261148 countsByYear W20502611482021 @default.
• W2050261148 countsByYear W20502611482022 @default.
• W2050261148 countsByYear W20502611482023 @default.
• W2050261148 crossrefType "journal-article" @default.
• W2050261148 hasAuthorship W2050261148A5027253014 @default.
• W2050261148 hasAuthorship W2050261148A5040936050 @default.
• W2050261148 hasAuthorship W2050261148A5073097748 @default.
• W2050261148 hasAuthorship W2050261148A5074400934 @default.
• W2050261148 hasBestOaLocation W20502611482 @default.
• W2050261148 hasConcept C105702510 @default.
• W2050261148 hasConcept C136229726 @default.
• W2050261148 hasConcept C171056886 @default.
• W2050261148 hasConcept C185592680 @default.
• W2050261148 hasConcept C189165786 @default.
• W2050261148 hasConcept C190672674 @default.
• W2050261148 hasConcept C192562407 @default.
• W2050261148 hasConcept C207200792 @default.
• W2050261148 hasConcept C2776193487 @default.
• W2050261148 hasConcept C2779959927 @default.
• W2050261148 hasConcept C3763915 @default.
• W2050261148 hasConcept C49892992 @default.
• W2050261148 hasConcept C71924100 @default.
• W2050261148 hasConcept C86803240 @default.
• W2050261148 hasConcept C89429830 @default.
• W2050261148 hasConcept C95444343 @default.
• W2050261148 hasConceptScore W2050261148C105702510 @default.
• W2050261148 hasConceptScore W2050261148C136229726 @default.

• next