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• W2050293669 abstract "101 patients with a clinical suspicion of typhoid or paratyphoid (enteric) fever admitted to San Lazaro Hospital, Manila, Philippines, were studied by bacteriological culture of blood, rectal swab, urine and duodenal string capsule; 35 also had bacteriological culture of bone marrow aspirate. 44 of the patients were culture-confirmed as having enteric fever; the remainder were classified as non-enteric fever cases. Analysis of the pretreatment Widal agglutination titres of all patients revealed that using as a diagnostic criterion an antibody titre of ⩾ 1:80 to the O antigen of Salmonella typhi yielded a test specificity of 100%, although the corresponding sensitivity was only 64%. The sensitivity of the test could be increased to 80% by using different cut-off values for titres to flagellar antigens, but this concomitantly decreased the test specificity from 100 to 82%. The data indicate that a single pretreatment Widal test in suspected enteric fever cases is of definite diagnostic value, but that the results must be interpreted with caution and foreknowledge of the test#x0027;s shortcomings and limitations." @default.
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• W2050293669 date "1987-09-01" @default.
• W2050293669 modified "2023-10-13" @default.
• W2050293669 title "Diagnostic value of a single, pre-treatment Widal test in suspected enteric fever cases in the Philippines" @default.
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• W2050293669 doi "https://doi.org/10.1016/0035-9203(87)90056-3" @default.
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