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• W2050325384 abstract "Upconversion luminescent β-NaYF4:Yb3+, Er3+ nanoparticles (UCNPs) were encapsulated with uniform mesoporous silica shells, which were further modified with poly(ethylene glycol) (PEG) and cancer-targeting ligand folic acid (FA), resulting in the formation of water-dispersible and biologically functionalized core–shell structured UCNPs@mSiO2 nanoparticles with an overall average size of around 80 nm. The obtained multifunctional nanocomposite spheres can be performed as an anti-cancer drug delivery carrier and applied for cell imaging. It is found that anti-cancer drug doxorubicin hydrochloride (DOX) can be absorbed into UCNPs@mSiO2-PEG/FA nanospheres and released in a pH-sensitive pattern. In vitro cell cytotoxicity tests on cancer cells verified that DOX-loaded UCNPs@mSiO2-PEG/FA nanospheres exhibited greater cytotoxicity with respect to free DOX and DOX-loaded UCNPs@mSiO2-PEG at the same concentrations, owing to the increase of cell uptake of anti-cancer drug delivery vehicles mediated by the FA receptor. Moreover, the upconversion luminescence image of UCNPs@mSiO2-PEG/FA taken up by cells shows green emission under 980 nm infrared laser excitation, making the UCNPs@mSiO2-PEG/FA nanocomposite spheres promising candidates as bioimaging agents. These findings highlight the promise of the highly versatile multifunctional nanoparticles for simultaneous imaging and therapeutic applications." @default.
• W2050325384 created "2016-06-24" @default.
• W2050325384 creator A5024972359 @default.
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• W2050325384 creator A5067162181 @default.
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• W2050325384 creator A5089122690 @default.
• W2050325384 date "2013-01-01" @default.
• W2050325384 modified "2023-10-13" @default.
• W2050325384 title "A facile fabrication of upconversion luminescent and mesoporous core–shell structured β-NaYF₄:Yb³⁺, Er³⁺@mSiO₂nanocomposite spheres for anti-cancer drug delivery and cell imaging" @default.
• W2050325384 cites W1963877576 @default.
• W2050325384 cites W1964238882 @default.
• W2050325384 cites W1964991943 @default.
• W2050325384 cites W1972038166 @default.
• W2050325384 cites W1972539393 @default.
• W2050325384 cites W1975139160 @default.
• W2050325384 cites W1976178939 @default.
• W2050325384 cites W1980363533 @default.
• W2050325384 cites W1981825595 @default.
• W2050325384 cites W1989960292 @default.
• W2050325384 cites W1990845976 @default.
• W2050325384 cites W1993169829 @default.
• W2050325384 cites W1994460217 @default.
• W2050325384 cites W2001168539 @default.
• W2050325384 cites W2008086056 @default.
• W2050325384 cites W2010664589 @default.
• W2050325384 cites W2010986334 @default.
• W2050325384 cites W2011956949 @default.
• W2050325384 cites W2014197436 @default.
• W2050325384 cites W2019138527 @default.
• W2050325384 cites W2028434426 @default.
• W2050325384 cites W2030235507 @default.
• W2050325384 cites W2030393917 @default.
• W2050325384 cites W2035462040 @default.
• W2050325384 cites W2039482831 @default.
• W2050325384 cites W2042432005 @default.
• W2050325384 cites W2047651080 @default.
• W2050325384 cites W2053553345 @default.
• W2050325384 cites W2055776993 @default.
• W2050325384 cites W2055870112 @default.
• W2050325384 cites W2056069790 @default.
• W2050325384 cites W2056324400 @default.
• W2050325384 cites W2057179996 @default.
• W2050325384 cites W2057675099 @default.
• W2050325384 cites W2059898245 @default.
• W2050325384 cites W2062293597 @default.
• W2050325384 cites W2066182057 @default.
• W2050325384 cites W2069289981 @default.
• W2050325384 cites W2076500439 @default.
• W2050325384 cites W2078107514 @default.
• W2050325384 cites W2082049032 @default.
• W2050325384 cites W2082556174 @default.
• W2050325384 cites W2083182800 @default.
• W2050325384 cites W2083208573 @default.
• W2050325384 cites W2087762907 @default.
• W2050325384 cites W2087785909 @default.
• W2050325384 cites W2089827717 @default.
• W2050325384 cites W2097532530 @default.
• W2050325384 cites W2098875662 @default.
• W2050325384 cites W2100312761 @default.
• W2050325384 cites W2102545819 @default.
• W2050325384 cites W2106192448 @default.
• W2050325384 cites W2115467182 @default.
• W2050325384 cites W2118517799 @default.
• W2050325384 cites W2126043133 @default.
• W2050325384 cites W2127217401 @default.
• W2050325384 cites W2130002810 @default.
• W2050325384 cites W2131290879 @default.
• W2050325384 cites W2137371056 @default.
• W2050325384 cites W2137374477 @default.
• W2050325384 cites W2139998115 @default.
• W2050325384 cites W2144308433 @default.
• W2050325384 cites W2149183402 @default.
• W2050325384 cites W2153164343 @default.
• W2050325384 cites W2161110122 @default.
• W2050325384 cites W2166395219 @default.
• W2050325384 cites W2169828908 @default.
• W2050325384 cites W2313628040 @default.
• W2050325384 cites W2316920904 @default.
• W2050325384 cites W2317180730 @default.
• W2050325384 cites W2329684687 @default.
• W2050325384 cites W2331540676 @default.
• W2050325384 cites W2335343707 @default.
• W2050325384 cites W3023255929 @default.
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• W2050325384 doi "https://doi.org/10.1039/c2bm00087c" @default.
• W2050325384 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32481801" @default.
• W2050325384 hasPublicationYear "2013" @default.
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