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- W2050334292 abstract "Peanut allergy is one of the most severe and common food allergies. Peanut molecular component testing for IgE to Ara h 1, 2, 3, 8, and 9 can potentially assist allergists with the stratification of patients. A retrospective review was performed over the first ten months of the testing for IgE to Ara h 1, 2, 3, 8, and 9 (Phadia), utilizing data with de-identified patient health information, compiled into risk groups based on current research utilizing a cutoff of 0.1 kU/L positive test, and evaluated based on patient age. Overall, 66% of samples were positive for Ara h 2, which carries the highest risk for anaphylaxis. However, in patients <10 years old this percentage rose to 75%. Of these samples, 13% were positive for only Ara h 2; 54% were positive for Ara h 1, 2, and 3. Positivity for Ara h 9 with or without Ara h 8 positivity accounted for 2.2% of samples and did not vary based on patient age. In the complete sample set only 7% of samples were positive for Ara h 8 alone, but samples from patient’s >18 this percentage rose to 14%. Molecular component allergy testing represents a major step forward in diagnosing and assessing risk for peanut allergic individuals. A significant rate of high risk identification indicates the importance of this information for patients and their families. Additional studies and subsequent practice guidelines are likely to emerge in the near future with component testing now available for clinical use." @default.
- W2050334292 created "2016-06-24" @default.
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- W2050334292 date "2014-02-01" @default.
- W2050334292 modified "2023-09-25" @default.
- W2050334292 title "Molecular Component Testing For Peanut Allergy Reactivity Differs Based On Age" @default.
- W2050334292 doi "https://doi.org/10.1016/j.jaci.2013.12.409" @default.
- W2050334292 hasPublicationYear "2014" @default.
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