FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050342016> ?p ?o ?g. }

• W2050342016 endingPage "219" @default.
• W2050342016 startingPage "214" @default.
• W2050342016 abstract "One model of breast tumorigenesis postulates a sequential evolution from normal to proliferative epithelium and eventually to neoplasia, but genetic data to support this progression have been limited. We wished to determine whether atypical hyperplasia (AH), a proliferative lesion conventionally classified and treated as benign, but associated with an increased risk of developing carcinoma, might show evidence of genetic abnormalities. Using the polymerase chain reaction (PCR), we examined DNA extracted from 12 separate AH lesions, from six breast cancer patients' paraffin-embedded tissue specimens, for alterations in microsatellite repeat sequences. Five of 12 AH lesions, from three of six patients, demonstrated alterations in microsatellite sequences in patterns indicating that the AH lesions are monoclonal or contain a substantial monoclonal component. We conclude that a subset of AH lesions from patients with breast cancer are characterized by monoclonal microsatellite alterations; therefore, they may already be neoplastic. This finding lends support to one postulated sequence of breast tumorigenesis and suggests that some type of genetic instability may play a role early in breast tumor development." @default.
• W2050342016 created "2016-06-24" @default.
• W2050342016 creator A5006333456 @default.
• W2050342016 creator A5029271412 @default.
• W2050342016 creator A5059447726 @default.
• W2050342016 creator A5062823151 @default.
• W2050342016 creator A5083735394 @default.
• W2050342016 date "1997-02-01" @default.
• W2050342016 modified "2023-10-16" @default.
• W2050342016 title "Microsatellite alterations indicating monoclonality in atypical hyperplasias associated with breast cancer" @default.
• W2050342016 cites W1965217852 @default.
• W2050342016 cites W1967304777 @default.
• W2050342016 cites W1982395246 @default.
• W2050342016 cites W1986937402 @default.
• W2050342016 cites W1991949008 @default.
• W2050342016 cites W1995819860 @default.
• W2050342016 cites W1999404265 @default.
• W2050342016 cites W2011719683 @default.
• W2050342016 cites W2035685670 @default.
• W2050342016 cites W2036534913 @default.
• W2050342016 cites W2042275105 @default.
• W2050342016 cites W2044643325 @default.
• W2050342016 cites W2044809539 @default.
• W2050342016 cites W2045638653 @default.
• W2050342016 cites W2060408155 @default.
• W2050342016 cites W2065479774 @default.
• W2050342016 cites W2071762482 @default.
• W2050342016 cites W2082014317 @default.
• W2050342016 cites W2084940248 @default.
• W2050342016 cites W2088316555 @default.
• W2050342016 cites W2092508315 @default.
• W2050342016 cites W2154181923 @default.
• W2050342016 cites W2158708815 @default.
• W2050342016 cites W2290292930 @default.
• W2050342016 cites W2306939951 @default.
• W2050342016 cites W2325716909 @default.
• W2050342016 cites W2328561181 @default.
• W2050342016 cites W2335942423 @default.
• W2050342016 cites W2408721985 @default.
• W2050342016 cites W2413971895 @default.
• W2050342016 cites W267182146 @default.
• W2050342016 doi "https://doi.org/10.1016/s0046-8177(97)90109-x" @default.
• W2050342016 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9023405" @default.
• W2050342016 hasPublicationYear "1997" @default.
• W2050342016 type Work @default.
• W2050342016 sameAs 2050342016 @default.
• W2050342016 citedByCount "42" @default.
• W2050342016 countsByYear W20503420162012 @default.
• W2050342016 countsByYear W20503420162017 @default.
• W2050342016 countsByYear W20503420162018 @default.
• W2050342016 crossrefType "journal-article" @default.
• W2050342016 hasAuthorship W2050342016A5006333456 @default.
• W2050342016 hasAuthorship W2050342016A5029271412 @default.
• W2050342016 hasAuthorship W2050342016A5059447726 @default.
• W2050342016 hasAuthorship W2050342016A5062823151 @default.
• W2050342016 hasAuthorship W2050342016A5083735394 @default.
• W2050342016 hasBestOaLocation W20503420161 @default.
• W2050342016 hasConcept C104317684 @default.
• W2050342016 hasConcept C121608353 @default.
• W2050342016 hasConcept C142724271 @default.
• W2050342016 hasConcept C159654299 @default.
• W2050342016 hasConcept C163864487 @default.
• W2050342016 hasConcept C180754005 @default.
• W2050342016 hasConcept C2777546739 @default.
• W2050342016 hasConcept C2777562237 @default.
• W2050342016 hasConcept C2777661416 @default.
• W2050342016 hasConcept C2779767149 @default.
• W2050342016 hasConcept C2781156865 @default.
• W2050342016 hasConcept C49105822 @default.
• W2050342016 hasConcept C502942594 @default.
• W2050342016 hasConcept C530470458 @default.
• W2050342016 hasConcept C542903549 @default.
• W2050342016 hasConcept C54355233 @default.
• W2050342016 hasConcept C555283112 @default.
• W2050342016 hasConcept C61320498 @default.
• W2050342016 hasConcept C71924100 @default.
• W2050342016 hasConcept C86803240 @default.
• W2050342016 hasConceptScore W2050342016C104317684 @default.
• W2050342016 hasConceptScore W2050342016C121608353 @default.
• W2050342016 hasConceptScore W2050342016C142724271 @default.
• W2050342016 hasConceptScore W2050342016C159654299 @default.
• W2050342016 hasConceptScore W2050342016C163864487 @default.
• W2050342016 hasConceptScore W2050342016C180754005 @default.
• W2050342016 hasConceptScore W2050342016C2777546739 @default.
• W2050342016 hasConceptScore W2050342016C2777562237 @default.
• W2050342016 hasConceptScore W2050342016C2777661416 @default.
• W2050342016 hasConceptScore W2050342016C2779767149 @default.
• W2050342016 hasConceptScore W2050342016C2781156865 @default.
• W2050342016 hasConceptScore W2050342016C49105822 @default.
• W2050342016 hasConceptScore W2050342016C502942594 @default.
• W2050342016 hasConceptScore W2050342016C530470458 @default.
• W2050342016 hasConceptScore W2050342016C542903549 @default.
• W2050342016 hasConceptScore W2050342016C54355233 @default.
• W2050342016 hasConceptScore W2050342016C555283112 @default.
• W2050342016 hasConceptScore W2050342016C61320498 @default.
• W2050342016 hasConceptScore W2050342016C71924100 @default.
• W2050342016 hasConceptScore W2050342016C86803240 @default.
• W2050342016 hasIssue "2" @default.

• next