Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050355904> ?p ?o ?g. }
- W2050355904 endingPage "136" @default.
- W2050355904 startingPage "129" @default.
- W2050355904 abstract "Chronic obstructive pulmonary disease (COPD) is a major health problem. Genetic factors that contribute to the disease have been postulated. The pulmonary surfactant protein B (SP-B), which is essential for normal lung function, is considered as a candidate gene for COPD in this case-control study. We studied the SP-B intron 4 size variants in 346 individuals. This group consisted of 118 patients with chronic bronchitis or COPD, including 24 patients with acute respiratory failure (ARF) in COPD, 118 matched controls without pulmonary disease and 110 healthy individuals (population control). The frequency of intron 4 variants was similar in either control group (10.9%, 14.4%, respectively), with a small increase in the COPD group (18.6%). This increase was due to a high increase of intron 4 variants in the ARF subgroup (37.5%, p = 0.003, OR 4.9, 95% CI: 1.76-13.6). The data indicate that SP-B intron 4 variants may associate with increased risk of ARF in COPD and may be used as a marker of susceptibility in this disease subgroup." @default.
- W2050355904 created "2016-06-24" @default.
- W2050355904 creator A5004848537 @default.
- W2050355904 creator A5006677665 @default.
- W2050355904 creator A5018131627 @default.
- W2050355904 creator A5037456457 @default.
- W2050355904 creator A5045307901 @default.
- W2050355904 creator A5061822883 @default.
- W2050355904 date "2002-01-01" @default.
- W2050355904 modified "2023-10-18" @default.
- W2050355904 title "Surfactant Protein B Intron 4 Variation in German Patients with COPD and Acute Respiratory Failure" @default.
- W2050355904 cites W1504213234 @default.
- W2050355904 cites W169384312 @default.
- W2050355904 cites W1943743677 @default.
- W2050355904 cites W1971974464 @default.
- W2050355904 cites W1973402680 @default.
- W2050355904 cites W1974977343 @default.
- W2050355904 cites W1983125679 @default.
- W2050355904 cites W1990402565 @default.
- W2050355904 cites W1997244165 @default.
- W2050355904 cites W2002641136 @default.
- W2050355904 cites W2008512736 @default.
- W2050355904 cites W2014902682 @default.
- W2050355904 cites W2018185831 @default.
- W2050355904 cites W2018953468 @default.
- W2050355904 cites W2019094071 @default.
- W2050355904 cites W2032960138 @default.
- W2050355904 cites W2054933658 @default.
- W2050355904 cites W2071496092 @default.
- W2050355904 cites W2093314252 @default.
- W2050355904 cites W2128551817 @default.
- W2050355904 cites W2138312725 @default.
- W2050355904 cites W2138605912 @default.
- W2050355904 cites W2146264666 @default.
- W2050355904 cites W2167445139 @default.
- W2050355904 cites W2178896288 @default.
- W2050355904 cites W2284648139 @default.
- W2050355904 cites W2339550260 @default.
- W2050355904 cites W2411220909 @default.
- W2050355904 cites W2465211765 @default.
- W2050355904 doi "https://doi.org/10.1155/2002/194075" @default.
- W2050355904 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3851100" @default.
- W2050355904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12515908" @default.
- W2050355904 hasPublicationYear "2002" @default.
- W2050355904 type Work @default.
- W2050355904 sameAs 2050355904 @default.
- W2050355904 citedByCount "37" @default.
- W2050355904 countsByYear W20503559042012 @default.
- W2050355904 countsByYear W20503559042013 @default.
- W2050355904 countsByYear W20503559042017 @default.
- W2050355904 countsByYear W20503559042020 @default.
- W2050355904 countsByYear W20503559042021 @default.
- W2050355904 countsByYear W20503559042022 @default.
- W2050355904 crossrefType "journal-article" @default.
- W2050355904 hasAuthorship W2050355904A5004848537 @default.
- W2050355904 hasAuthorship W2050355904A5006677665 @default.
- W2050355904 hasAuthorship W2050355904A5018131627 @default.
- W2050355904 hasAuthorship W2050355904A5037456457 @default.
- W2050355904 hasAuthorship W2050355904A5045307901 @default.
- W2050355904 hasAuthorship W2050355904A5061822883 @default.
- W2050355904 hasBestOaLocation W20503559041 @default.
- W2050355904 hasConcept C104317684 @default.
- W2050355904 hasConcept C126322002 @default.
- W2050355904 hasConcept C146304588 @default.
- W2050355904 hasConcept C2776780178 @default.
- W2050355904 hasConcept C2992694001 @default.
- W2050355904 hasConcept C54355233 @default.
- W2050355904 hasConcept C71924100 @default.
- W2050355904 hasConcept C86803240 @default.
- W2050355904 hasConcept C90924648 @default.
- W2050355904 hasConcept C94671646 @default.
- W2050355904 hasConceptScore W2050355904C104317684 @default.
- W2050355904 hasConceptScore W2050355904C126322002 @default.
- W2050355904 hasConceptScore W2050355904C146304588 @default.
- W2050355904 hasConceptScore W2050355904C2776780178 @default.
- W2050355904 hasConceptScore W2050355904C2992694001 @default.
- W2050355904 hasConceptScore W2050355904C54355233 @default.
- W2050355904 hasConceptScore W2050355904C71924100 @default.
- W2050355904 hasConceptScore W2050355904C86803240 @default.
- W2050355904 hasConceptScore W2050355904C90924648 @default.
- W2050355904 hasConceptScore W2050355904C94671646 @default.
- W2050355904 hasFunder F4320321114 @default.
- W2050355904 hasIssue "3" @default.
- W2050355904 hasLocation W20503559041 @default.
- W2050355904 hasLocation W20503559042 @default.
- W2050355904 hasLocation W20503559043 @default.
- W2050355904 hasLocation W20503559044 @default.
- W2050355904 hasLocation W20503559045 @default.
- W2050355904 hasOpenAccess W2050355904 @default.
- W2050355904 hasPrimaryLocation W20503559041 @default.
- W2050355904 hasRelatedWork W2120902800 @default.
- W2050355904 hasRelatedWork W2156696721 @default.
- W2050355904 hasRelatedWork W2168449172 @default.
- W2050355904 hasRelatedWork W2326106380 @default.
- W2050355904 hasRelatedWork W2362299873 @default.
- W2050355904 hasRelatedWork W2372071230 @default.
- W2050355904 hasRelatedWork W2425739747 @default.
- W2050355904 hasRelatedWork W2585577925 @default.