FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050355964> ?p ?o ?g. }

• W2050355964 endingPage "979" @default.
• W2050355964 startingPage "974" @default.
• W2050355964 abstract "Loperamide is a well-established antidiarrhoeal agent with effects on gastrointestinal motility. We have now shown that the drug influences ion transport. In isolated rabbit ileal mucosa loperamide caused a dose-related fall in potential difference and short-circuit current and reduced the serosa to mucosa flux of chloride. The electrical effects were inhibited by naloxone (10(-6)M) suggesting that they were mediated by opiate receptors. Loperamide (10(-6)M) inhibited secretion provoked by heat stable and heat labile E. coli toxins and by prostaglandin E2. We conclude that loperamide is able to inhibit secretion mediated by cAMP or cGNP, and that this may be relevant to its antidiarrhoeal properties." @default.
• W2050355964 created "2016-06-24" @default.
• W2050355964 creator A5016981472 @default.
• W2050355964 creator A5070022303 @default.
• W2050355964 creator A5085939269 @default.
• W2050355964 date "1982-11-01" @default.
• W2050355964 modified "2023-09-25" @default.
• W2050355964 title "Antidiarrhoeal activity of loperamide: studies of its influence on ion transport across rabbit ileal mucosa in vitro." @default.
• W2050355964 cites W107912336 @default.
• W2050355964 cites W1644325907 @default.
• W2050355964 cites W1806378557 @default.
• W2050355964 cites W1935414109 @default.
• W2050355964 cites W1964781019 @default.
• W2050355964 cites W1983901270 @default.
• W2050355964 cites W1992726845 @default.
• W2050355964 cites W1999903047 @default.
• W2050355964 cites W2013834680 @default.
• W2050355964 cites W202324211 @default.
• W2050355964 cites W2025183199 @default.
• W2050355964 cites W2055236608 @default.
• W2050355964 cites W2061029816 @default.
• W2050355964 cites W2088188089 @default.
• W2050355964 cites W2092253011 @default.
• W2050355964 cites W2119784436 @default.
• W2050355964 cites W2138243399 @default.
• W2050355964 cites W2401052533 @default.
• W2050355964 cites W2406805271 @default.
• W2050355964 cites W2431097602 @default.
• W2050355964 cites W2471775664 @default.
• W2050355964 cites W255478600 @default.
• W2050355964 cites W3028389194 @default.
• W2050355964 doi "https://doi.org/10.1136/gut.23.11.974" @default.
• W2050355964 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1419791" @default.
• W2050355964 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6751949" @default.
• W2050355964 hasPublicationYear "1982" @default.
• W2050355964 type Work @default.
• W2050355964 sameAs 2050355964 @default.
• W2050355964 citedByCount "49" @default.
• W2050355964 countsByYear W20503559642016 @default.
• W2050355964 countsByYear W20503559642018 @default.
• W2050355964 countsByYear W20503559642019 @default.
• W2050355964 countsByYear W20503559642020 @default.
• W2050355964 countsByYear W20503559642021 @default.
• W2050355964 countsByYear W20503559642022 @default.
• W2050355964 countsByYear W20503559642023 @default.
• W2050355964 crossrefType "journal-article" @default.
• W2050355964 hasAuthorship W2050355964A5016981472 @default.
• W2050355964 hasAuthorship W2050355964A5070022303 @default.
• W2050355964 hasAuthorship W2050355964A5085939269 @default.
• W2050355964 hasBestOaLocation W20503559641 @default.
• W2050355964 hasConcept C126322002 @default.
• W2050355964 hasConcept C134018914 @default.
• W2050355964 hasConcept C170493617 @default.
• W2050355964 hasConcept C185592680 @default.
• W2050355964 hasConcept C202751555 @default.
• W2050355964 hasConcept C2777573665 @default.
• W2050355964 hasConcept C2778229996 @default.
• W2050355964 hasConcept C2778750930 @default.
• W2050355964 hasConcept C2778814440 @default.
• W2050355964 hasConcept C2779802037 @default.
• W2050355964 hasConcept C2781063702 @default.
• W2050355964 hasConcept C3019368612 @default.
• W2050355964 hasConcept C49039625 @default.
• W2050355964 hasConcept C55493867 @default.
• W2050355964 hasConcept C58207958 @default.
• W2050355964 hasConcept C71924100 @default.
• W2050355964 hasConcept C86803240 @default.
• W2050355964 hasConcept C95444343 @default.
• W2050355964 hasConcept C98274493 @default.
• W2050355964 hasConceptScore W2050355964C126322002 @default.
• W2050355964 hasConceptScore W2050355964C134018914 @default.
• W2050355964 hasConceptScore W2050355964C170493617 @default.
• W2050355964 hasConceptScore W2050355964C185592680 @default.
• W2050355964 hasConceptScore W2050355964C202751555 @default.
• W2050355964 hasConceptScore W2050355964C2777573665 @default.
• W2050355964 hasConceptScore W2050355964C2778229996 @default.
• W2050355964 hasConceptScore W2050355964C2778750930 @default.
• W2050355964 hasConceptScore W2050355964C2778814440 @default.
• W2050355964 hasConceptScore W2050355964C2779802037 @default.
• W2050355964 hasConceptScore W2050355964C2781063702 @default.
• W2050355964 hasConceptScore W2050355964C3019368612 @default.
• W2050355964 hasConceptScore W2050355964C49039625 @default.
• W2050355964 hasConceptScore W2050355964C55493867 @default.
• W2050355964 hasConceptScore W2050355964C58207958 @default.
• W2050355964 hasConceptScore W2050355964C71924100 @default.
• W2050355964 hasConceptScore W2050355964C86803240 @default.
• W2050355964 hasConceptScore W2050355964C95444343 @default.
• W2050355964 hasConceptScore W2050355964C98274493 @default.
• W2050355964 hasIssue "11" @default.
• W2050355964 hasLocation W20503559641 @default.
• W2050355964 hasLocation W20503559642 @default.
• W2050355964 hasLocation W20503559643 @default.
• W2050355964 hasLocation W20503559644 @default.
• W2050355964 hasOpenAccess W2050355964 @default.
• W2050355964 hasPrimaryLocation W20503559641 @default.
• W2050355964 hasRelatedWork W1971852532 @default.
• W2050355964 hasRelatedWork W1975757436 @default.
• W2050355964 hasRelatedWork W2020884724 @default.

• next