FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050390436> ?p ?o ?g. }

• W2050390436 endingPage "761" @default.
• W2050390436 startingPage "754" @default.
• W2050390436 abstract "Purpose of review To review state of art and relevant advances in the molecular biology and management of ependymomas of the adult. Recent findings Ependymomas of the adult are uncommon neoplasms of the central nervous system, and may occur either in the brain or the spinal cord. Compared with intracranial ependymomas, spinal ependymomas are less frequent and exhibit a better prognosis. Studies performed on genetic changes in ependymoma provide some insight into the pathogenesis and prognostic markers and yield new therapeutic targets, particularly focused on signal transduction modulators. The majority of studies have shown a major impact of extent of resection; thus, a complete resection must be performed, whenever possible, at first surgery or at reoperation. Involved field radiotherapy is recommended for anaplastic or incompletely resected grade II tumors. Craniospinal irradiation is reserved for metastatic disease. Chemotherapy is not advocated as primary treatment, and is best utilized as salvage treatment for patients failing surgery and radiotherapy. Summary Owing to the rarity of the disease, the literature regarding ependymomas in adults is scarce and limited to retrospective series. Thus, the level of evidence regarding therapeutic strategies is low and universally accepted guidelines are lacking. Molecular biology studies suggest some potential new therapeutic targets." @default.
• W2050390436 created "2016-06-24" @default.
• W2050390436 creator A5064627876 @default.
• W2050390436 creator A5089715484 @default.
• W2050390436 creator A5090731176 @default.
• W2050390436 date "2008-12-01" @default.
• W2050390436 modified "2023-10-14" @default.
• W2050390436 title "Ependymomas of the adult: molecular biology and treatment" @default.
• W2050390436 cites W138913518 @default.
• W2050390436 cites W1529974040 @default.
• W2050390436 cites W1531222221 @default.
• W2050390436 cites W1597147149 @default.
• W2050390436 cites W1685459807 @default.
• W2050390436 cites W1859278226 @default.
• W2050390436 cites W196448128 @default.
• W2050390436 cites W1964606089 @default.
• W2050390436 cites W1965952193 @default.
• W2050390436 cites W1967075737 @default.
• W2050390436 cites W1970547700 @default.
• W2050390436 cites W1978354734 @default.
• W2050390436 cites W1978396373 @default.
• W2050390436 cites W1981207976 @default.
• W2050390436 cites W1982660927 @default.
• W2050390436 cites W1984757982 @default.
• W2050390436 cites W1985052767 @default.
• W2050390436 cites W1985848413 @default.
• W2050390436 cites W1988042084 @default.
• W2050390436 cites W1992149017 @default.
• W2050390436 cites W1996449170 @default.
• W2050390436 cites W2000446369 @default.
• W2050390436 cites W2008123285 @default.
• W2050390436 cites W2009239522 @default.
• W2050390436 cites W2009976209 @default.
• W2050390436 cites W2012363541 @default.
• W2050390436 cites W2015117760 @default.
• W2050390436 cites W2015674660 @default.
• W2050390436 cites W2019879146 @default.
• W2050390436 cites W2026560962 @default.
• W2050390436 cites W2030638234 @default.
• W2050390436 cites W2032144018 @default.
• W2050390436 cites W2032180303 @default.
• W2050390436 cites W2035303288 @default.
• W2050390436 cites W2039909007 @default.
• W2050390436 cites W2041480426 @default.
• W2050390436 cites W2041966836 @default.
• W2050390436 cites W2042373659 @default.
• W2050390436 cites W2043321551 @default.
• W2050390436 cites W2047468357 @default.
• W2050390436 cites W2049192274 @default.
• W2050390436 cites W2052461445 @default.
• W2050390436 cites W2056818939 @default.
• W2050390436 cites W2060695368 @default.
• W2050390436 cites W2060762040 @default.
• W2050390436 cites W2066343175 @default.
• W2050390436 cites W2068284127 @default.
• W2050390436 cites W2069840070 @default.
• W2050390436 cites W2073861399 @default.
• W2050390436 cites W2075943369 @default.
• W2050390436 cites W2077934654 @default.
• W2050390436 cites W2078423048 @default.
• W2050390436 cites W2078790854 @default.
• W2050390436 cites W2080079617 @default.
• W2050390436 cites W2081048471 @default.
• W2050390436 cites W2084315213 @default.
• W2050390436 cites W2086075544 @default.
• W2050390436 cites W2087948949 @default.
• W2050390436 cites W2096244345 @default.
• W2050390436 cites W2097251424 @default.
• W2050390436 cites W2098573966 @default.
• W2050390436 cites W2103562915 @default.
• W2050390436 cites W2105100844 @default.
• W2050390436 cites W2105414327 @default.
• W2050390436 cites W2110689735 @default.
• W2050390436 cites W2111586569 @default.
• W2050390436 cites W2112158977 @default.
• W2050390436 cites W2113379379 @default.
• W2050390436 cites W2113605685 @default.
• W2050390436 cites W2113942802 @default.
• W2050390436 cites W2121152245 @default.
• W2050390436 cites W2124071466 @default.
• W2050390436 cites W2124215206 @default.
• W2050390436 cites W2125724629 @default.
• W2050390436 cites W2126744367 @default.
• W2050390436 cites W2132327237 @default.
• W2050390436 cites W2134014889 @default.
• W2050390436 cites W2134479723 @default.
• W2050390436 cites W2138320845 @default.
• W2050390436 cites W2141403353 @default.
• W2050390436 cites W2142388038 @default.
• W2050390436 cites W2143247269 @default.
• W2050390436 cites W2143619463 @default.
• W2050390436 cites W2143665087 @default.
• W2050390436 cites W2147077571 @default.
• W2050390436 cites W2152489395 @default.
• W2050390436 cites W2158457275 @default.
• W2050390436 cites W2160034281 @default.
• W2050390436 cites W2167810028 @default.
• W2050390436 cites W2169702485 @default.

• next