FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050394939> ?p ?o ?g. }

• W2050394939 endingPage "107" @default.
• W2050394939 startingPage "101" @default.
• W2050394939 abstract "This study aimed to formulate and evaluate nasal delivery systems containing ondansetron hydrochloride. In the in vitro study, the permeation rate with the addition of 10% polyethylene glycol 300 (PEG 300) to aqueous solution containing 0.01% benzalkonium chloride (BC) and 10% sulfobutylether beta-cyclodextrin sodium salt (SBCD) was somewhat more rapid up to 1.5h compared to the addition of 10% PG. The permeation flux increased as the drug concentration increased regardless of the vehicles used. The addition of nicotinamide or chitosan to aqueous drug solution (40 mg/ml) with 10% PEG 300 and 0.01% BC rather decreased permeation rate and delayed lag time. Even though cyclodextrins including SBCD or dimethyl-ss-cyclodextrin failed to show permeation enhancing effects of ondansetron hydrochloride, the addition of 10% SBCD to aqueous solution containing 10% PEG 300 and 0.01% BC could be a good candidate for ondansetron nasal delivery systems because of its safety profile, stable storage in refrigerator and solubilizing effect. With the above formulation, the nasal delivery system increased AUC0-2h and Cmax by 2.1 and 1.7 times compared to those of oral delivery, respectively while there was no difference found in AUC0-2h with intravenous administration. Therefore, the nasal delivery system of ondansetron hydrochloride formulated in this study was feasible for nasal administration." @default.
• W2050394939 created "2016-06-24" @default.
• W2050394939 creator A5004059878 @default.
• W2050394939 creator A5018216715 @default.
• W2050394939 creator A5057992207 @default.
• W2050394939 date "2008-02-12" @default.
• W2050394939 modified "2023-09-24" @default.
• W2050394939 title "Formulation and evaluation of ondansetron nasal delivery systems" @default.
• W2050394939 cites W150218416 @default.
• W2050394939 cites W1986774418 @default.
• W2050394939 cites W1989341939 @default.
• W2050394939 cites W1991260622 @default.
• W2050394939 cites W2001570423 @default.
• W2050394939 cites W2009548189 @default.
• W2050394939 cites W2014191079 @default.
• W2050394939 cites W2016587975 @default.
• W2050394939 cites W2023694826 @default.
• W2050394939 cites W2030938224 @default.
• W2050394939 cites W2034649196 @default.
• W2050394939 cites W2041399624 @default.
• W2050394939 cites W2043291920 @default.
• W2050394939 cites W2047603891 @default.
• W2050394939 cites W2051587929 @default.
• W2050394939 cites W2053369915 @default.
• W2050394939 cites W2064620211 @default.
• W2050394939 cites W2076288067 @default.
• W2050394939 cites W2080796107 @default.
• W2050394939 cites W2092632621 @default.
• W2050394939 cites W2133037325 @default.
• W2050394939 cites W2147654175 @default.
• W2050394939 cites W2153494490 @default.
• W2050394939 cites W47464580 @default.
• W2050394939 cites W597514109 @default.
• W2050394939 cites W771869994 @default.
• W2050394939 doi "https://doi.org/10.1016/j.ijpharm.2007.07.028" @default.
• W2050394939 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17822864" @default.
• W2050394939 hasPublicationYear "2008" @default.
• W2050394939 type Work @default.
• W2050394939 sameAs 2050394939 @default.
• W2050394939 citedByCount "50" @default.
• W2050394939 countsByYear W20503949392012 @default.
• W2050394939 countsByYear W20503949392013 @default.
• W2050394939 countsByYear W20503949392014 @default.
• W2050394939 countsByYear W20503949392015 @default.
• W2050394939 countsByYear W20503949392017 @default.
• W2050394939 countsByYear W20503949392018 @default.
• W2050394939 countsByYear W20503949392019 @default.
• W2050394939 countsByYear W20503949392020 @default.
• W2050394939 countsByYear W20503949392021 @default.
• W2050394939 countsByYear W20503949392022 @default.
• W2050394939 countsByYear W20503949392023 @default.
• W2050394939 crossrefType "journal-article" @default.
• W2050394939 hasAuthorship W2050394939A5004059878 @default.
• W2050394939 hasAuthorship W2050394939A5018216715 @default.
• W2050394939 hasAuthorship W2050394939A5057992207 @default.
• W2050394939 hasConcept C10138342 @default.
• W2050394939 hasConcept C112705442 @default.
• W2050394939 hasConcept C162324750 @default.
• W2050394939 hasConcept C178790620 @default.
• W2050394939 hasConcept C185592680 @default.
• W2050394939 hasConcept C201253974 @default.
• W2050394939 hasConcept C22979827 @default.
• W2050394939 hasConcept C2776964284 @default.
• W2050394939 hasConcept C2777056448 @default.
• W2050394939 hasConcept C2777170512 @default.
• W2050394939 hasConcept C2779433975 @default.
• W2050394939 hasConcept C2780852908 @default.
• W2050394939 hasConcept C41625074 @default.
• W2050394939 hasConcept C42219234 @default.
• W2050394939 hasConcept C43617362 @default.
• W2050394939 hasConcept C50670333 @default.
• W2050394939 hasConcept C54400483 @default.
• W2050394939 hasConcept C55493867 @default.
• W2050394939 hasConcept C71924100 @default.
• W2050394939 hasConcept C85663871 @default.
• W2050394939 hasConcept C98274493 @default.
• W2050394939 hasConceptScore W2050394939C10138342 @default.
• W2050394939 hasConceptScore W2050394939C112705442 @default.
• W2050394939 hasConceptScore W2050394939C162324750 @default.
• W2050394939 hasConceptScore W2050394939C178790620 @default.
• W2050394939 hasConceptScore W2050394939C185592680 @default.
• W2050394939 hasConceptScore W2050394939C201253974 @default.
• W2050394939 hasConceptScore W2050394939C22979827 @default.
• W2050394939 hasConceptScore W2050394939C2776964284 @default.
• W2050394939 hasConceptScore W2050394939C2777056448 @default.
• W2050394939 hasConceptScore W2050394939C2777170512 @default.
• W2050394939 hasConceptScore W2050394939C2779433975 @default.
• W2050394939 hasConceptScore W2050394939C2780852908 @default.
• W2050394939 hasConceptScore W2050394939C41625074 @default.
• W2050394939 hasConceptScore W2050394939C42219234 @default.
• W2050394939 hasConceptScore W2050394939C43617362 @default.
• W2050394939 hasConceptScore W2050394939C50670333 @default.
• W2050394939 hasConceptScore W2050394939C54400483 @default.
• W2050394939 hasConceptScore W2050394939C55493867 @default.
• W2050394939 hasConceptScore W2050394939C71924100 @default.
• W2050394939 hasConceptScore W2050394939C85663871 @default.
• W2050394939 hasConceptScore W2050394939C98274493 @default.
• W2050394939 hasIssue "1-2" @default.

• next