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• W2050395164 endingPage "369" @default.
• W2050395164 startingPage "362" @default.
• W2050395164 abstract "Stem cells are fundamental units for achieving regenerative therapies, which leads naturally to a theoretical and experimental focus on these cells for therapeutic screening and intervention. A growing body of data in many tissue systems indicates that stem cell function is critically influenced by extrinsic signals derived from the microenvironment, or niche. In this vein, the stem cell niche represents a significant, and largely untapped, entry point for therapeutic modulation of stem cell behavior. This Perspective will discuss how the niche influences stem cells in homeostasis, in the progression of degenerative and malignant diseases, and in therapeutic strategies for tissue repair." @default.
• W2050395164 created "2016-06-24" @default.
• W2050395164 creator A5030798882 @default.
• W2050395164 date "2012-04-01" @default.
• W2050395164 modified "2023-10-14" @default.
• W2050395164 title "The Stem Cell Niche in Regenerative Medicine" @default.
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• W2050395164 doi "https://doi.org/10.1016/j.stem.2012.02.018" @default.
• W2050395164 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22482502" @default.
• W2050395164 hasPublicationYear "2012" @default.
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