FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050404953> ?p ?o ?g. }

• W2050404953 endingPage "96" @default.
• W2050404953 startingPage "90" @default.
• W2050404953 abstract "Human cytomegalovirus (HCMV) displays genetic polymorphisms. This variability may contribute to strain-specific tissue tropism and disease expression in HCMV-infected humans. To determine strain variability in a sequence and UL144 gene regions, 51 low-passage isolates from 44 HCMV-infected children were studied. Isolates were obtained from 28 healthy children attending child care centers in Iowa and from 16 congenitally infected infants born in Texas. Isolates demonstrated substantial nucleotide variation in each gene region. Phylogenetic analysis of a sequence variability allowed 39 isolates to be grouped into six clades. The largest clade contained 16 isolates with ≥ 95% nucleotide homology. Forty-eight of the 49 HCMV isolates yielding UL144 amplicons was grouped according to the clades described a few years ago [Lurain et al. (1999) Journal of Virology 73:10040–10050]. No linkage was observed among a sequence, UL144, and glycoprotein B (gB; UL55) polymorphisms. Four Texas and 11 Iowa isolates displayed ≥ 95% sequence homology for a sequence and UL144 regions and possessed identical gB genotypes. No relationship between UL144 polymorphisms and outcome of congenital HCMV infection was observed. These data indicate that HCMV strains circulating among young children have UL144 polymorphisms similar to those of HCMV strains excreted by immunocompromised adults. Identification of conserved nucleotide sequences among Iowa and Texas children suggests genetic stability and biologic importance of these gene regions. J. Med. Virol. 65:90–96, 2001. © 2001 Wiley-Liss, Inc." @default.
• W2050404953 created "2016-06-24" @default.
• W2050404953 creator A5011521959 @default.
• W2050404953 creator A5016645619 @default.
• W2050404953 creator A5049330731 @default.
• W2050404953 creator A5067038600 @default.
• W2050404953 creator A5072785945 @default.
• W2050404953 date "2001-01-01" @default.
• W2050404953 modified "2023-10-13" @default.
• W2050404953 title "Human cytomegalovirusa sequence and UL144 variability in strains from infected children" @default.
• W2050404953 cites W1545455594 @default.
• W2050404953 cites W1638089104 @default.
• W2050404953 cites W1754398785 @default.
• W2050404953 cites W1780875019 @default.
• W2050404953 cites W1966213591 @default.
• W2050404953 cites W1981522048 @default.
• W2050404953 cites W1994962035 @default.
• W2050404953 cites W2008183545 @default.
• W2050404953 cites W2010917934 @default.
• W2050404953 cites W2013748217 @default.
• W2050404953 cites W2033449145 @default.
• W2050404953 cites W2050966701 @default.
• W2050404953 cites W2079427812 @default.
• W2050404953 cites W2102162003 @default.
• W2050404953 cites W2109645534 @default.
• W2050404953 cites W2112704272 @default.
• W2050404953 cites W2132108466 @default.
• W2050404953 cites W2134186358 @default.
• W2050404953 cites W2140965613 @default.
• W2050404953 cites W2152216478 @default.
• W2050404953 doi "https://doi.org/10.1002/jmv.2006" @default.
• W2050404953 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11505449" @default.
• W2050404953 hasPublicationYear "2001" @default.
• W2050404953 type Work @default.
• W2050404953 sameAs 2050404953 @default.
• W2050404953 citedByCount "63" @default.
• W2050404953 countsByYear W20504049532012 @default.
• W2050404953 countsByYear W20504049532013 @default.
• W2050404953 countsByYear W20504049532014 @default.
• W2050404953 countsByYear W20504049532015 @default.
• W2050404953 countsByYear W20504049532017 @default.
• W2050404953 countsByYear W20504049532019 @default.
• W2050404953 countsByYear W20504049532021 @default.
• W2050404953 countsByYear W20504049532023 @default.
• W2050404953 crossrefType "journal-article" @default.
• W2050404953 hasAuthorship W2050404953A5011521959 @default.
• W2050404953 hasAuthorship W2050404953A5016645619 @default.
• W2050404953 hasAuthorship W2050404953A5049330731 @default.
• W2050404953 hasAuthorship W2050404953A5067038600 @default.
• W2050404953 hasAuthorship W2050404953A5072785945 @default.
• W2050404953 hasConcept C104317684 @default.
• W2050404953 hasConcept C135763542 @default.
• W2050404953 hasConcept C159047783 @default.
• W2050404953 hasConcept C165525559 @default.
• W2050404953 hasConcept C193252679 @default.
• W2050404953 hasConcept C2522874641 @default.
• W2050404953 hasConcept C2779820661 @default.
• W2050404953 hasConcept C33602714 @default.
• W2050404953 hasConcept C35693153 @default.
• W2050404953 hasConcept C44465124 @default.
• W2050404953 hasConcept C49105822 @default.
• W2050404953 hasConcept C54355233 @default.
• W2050404953 hasConcept C61053724 @default.
• W2050404953 hasConcept C68873052 @default.
• W2050404953 hasConcept C8185291 @default.
• W2050404953 hasConcept C84148353 @default.
• W2050404953 hasConcept C86803240 @default.
• W2050404953 hasConceptScore W2050404953C104317684 @default.
• W2050404953 hasConceptScore W2050404953C135763542 @default.
• W2050404953 hasConceptScore W2050404953C159047783 @default.
• W2050404953 hasConceptScore W2050404953C165525559 @default.
• W2050404953 hasConceptScore W2050404953C193252679 @default.
• W2050404953 hasConceptScore W2050404953C2522874641 @default.
• W2050404953 hasConceptScore W2050404953C2779820661 @default.
• W2050404953 hasConceptScore W2050404953C33602714 @default.
• W2050404953 hasConceptScore W2050404953C35693153 @default.
• W2050404953 hasConceptScore W2050404953C44465124 @default.
• W2050404953 hasConceptScore W2050404953C49105822 @default.
• W2050404953 hasConceptScore W2050404953C54355233 @default.
• W2050404953 hasConceptScore W2050404953C61053724 @default.
• W2050404953 hasConceptScore W2050404953C68873052 @default.
• W2050404953 hasConceptScore W2050404953C8185291 @default.
• W2050404953 hasConceptScore W2050404953C84148353 @default.
• W2050404953 hasConceptScore W2050404953C86803240 @default.
• W2050404953 hasIssue "1" @default.
• W2050404953 hasLocation W20504049531 @default.
• W2050404953 hasLocation W20504049532 @default.
• W2050404953 hasOpenAccess W2050404953 @default.
• W2050404953 hasPrimaryLocation W20504049531 @default.
• W2050404953 hasRelatedWork W138586086 @default.
• W2050404953 hasRelatedWork W1953735714 @default.
• W2050404953 hasRelatedWork W2001397790 @default.
• W2050404953 hasRelatedWork W2118640372 @default.
• W2050404953 hasRelatedWork W2118937969 @default.
• W2050404953 hasRelatedWork W2174387488 @default.
• W2050404953 hasRelatedWork W2384093552 @default.
• W2050404953 hasRelatedWork W4319761902 @default.
• W2050404953 hasRelatedWork W4366091465 @default.

• next