FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050433784> ?p ?o ?g. }

• W2050433784 endingPage "e27" @default.
• W2050433784 startingPage "e27" @default.
• W2050433784 abstract "Peptides often have conformational preferences. We simulated 133 peptide 8-mer fragments from six different proteins, sampled by replica-exchange molecular dynamics using Amber7 with a GB/SA (generalized-Born/solvent-accessible electrostatic approximation to water) implicit solvent. We found that 85 of the peptides have no preferred structure, while 48 of them converge to a preferred structure. In 85% of the converged cases (41 peptides), the structures found by the simulations bear some resemblance to their native structures, based on a coarse-grained backbone description. In particular, all seven of the β hairpins in the native structures contain a fragment in the turn that is highly structured. In the eight cases where the bioinformatics-based I-sites library picks out native-like structures, the present simulations are largely in agreement. Such physics-based modeling may be useful for identifying early nuclei in folding kinetics and for assisting in protein-structure prediction methods that utilize the assembly of peptide fragments." @default.
• W2050433784 created "2016-06-24" @default.
• W2050433784 creator A5013305919 @default.
• W2050433784 creator A5022589839 @default.
• W2050433784 date "2006-04-14" @default.
• W2050433784 modified "2023-10-17" @default.
• W2050433784 title "Folding Very Short Peptides Using Molecular Dynamics" @default.
• W2050433784 cites W1658649599 @default.
• W2050433784 cites W1960408443 @default.
• W2050433784 cites W1983563082 @default.
• W2050433784 cites W1985460288 @default.
• W2050433784 cites W1985504414 @default.
• W2050433784 cites W1991514145 @default.
• W2050433784 cites W1992152661 @default.
• W2050433784 cites W2014059004 @default.
• W2050433784 cites W2015195383 @default.
• W2050433784 cites W2019729866 @default.
• W2050433784 cites W2020768312 @default.
• W2050433784 cites W2031439885 @default.
• W2050433784 cites W2034647743 @default.
• W2050433784 cites W2036623301 @default.
• W2050433784 cites W2040809566 @default.
• W2050433784 cites W2047266963 @default.
• W2050433784 cites W2047510784 @default.
• W2050433784 cites W2049902088 @default.
• W2050433784 cites W2057553906 @default.
• W2050433784 cites W2058198562 @default.
• W2050433784 cites W2058651019 @default.
• W2050433784 cites W2065247480 @default.
• W2050433784 cites W2065864756 @default.
• W2050433784 cites W2073758233 @default.
• W2050433784 cites W2074978848 @default.
• W2050433784 cites W2074991560 @default.
• W2050433784 cites W2079492386 @default.
• W2050433784 cites W2080681712 @default.
• W2050433784 cites W2083939457 @default.
• W2050433784 cites W2092818861 @default.
• W2050433784 cites W2093381148 @default.
• W2050433784 cites W2094889474 @default.
• W2050433784 cites W2102849964 @default.
• W2050433784 cites W2105880172 @default.
• W2050433784 cites W2106140689 @default.
• W2050433784 cites W2107876005 @default.
• W2050433784 cites W2112154906 @default.
• W2050433784 cites W2112878090 @default.
• W2050433784 cites W2125380479 @default.
• W2050433784 cites W2128816059 @default.
• W2050433784 cites W2128954946 @default.
• W2050433784 cites W2131633716 @default.
• W2050433784 cites W2132820390 @default.
• W2050433784 cites W2135212862 @default.
• W2050433784 cites W2135469866 @default.
• W2050433784 cites W2142383894 @default.
• W2050433784 cites W2150627302 @default.
• W2050433784 cites W2152655599 @default.
• W2050433784 cites W2156879354 @default.
• W2050433784 cites W2170735789 @default.
• W2050433784 doi "https://doi.org/10.1371/journal.pcbi.0020027" @default.
• W2050433784 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1435986" @default.
• W2050433784 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16617376" @default.
• W2050433784 hasPublicationYear "2006" @default.
• W2050433784 type Work @default.
• W2050433784 sameAs 2050433784 @default.
• W2050433784 citedByCount "62" @default.
• W2050433784 countsByYear W20504337842012 @default.
• W2050433784 countsByYear W20504337842013 @default.
• W2050433784 countsByYear W20504337842014 @default.
• W2050433784 countsByYear W20504337842015 @default.
• W2050433784 countsByYear W20504337842016 @default.
• W2050433784 countsByYear W20504337842017 @default.
• W2050433784 countsByYear W20504337842018 @default.
• W2050433784 countsByYear W20504337842019 @default.
• W2050433784 countsByYear W20504337842020 @default.
• W2050433784 countsByYear W20504337842021 @default.
• W2050433784 countsByYear W20504337842022 @default.
• W2050433784 countsByYear W20504337842023 @default.
• W2050433784 crossrefType "journal-article" @default.
• W2050433784 hasAuthorship W2050433784A5013305919 @default.
• W2050433784 hasAuthorship W2050433784A5022589839 @default.
• W2050433784 hasBestOaLocation W20504337841 @default.
• W2050433784 hasConcept C119599485 @default.
• W2050433784 hasConcept C12554922 @default.
• W2050433784 hasConcept C127413603 @default.
• W2050433784 hasConcept C142362112 @default.
• W2050433784 hasConcept C147597530 @default.
• W2050433784 hasConcept C152769699 @default.
• W2050433784 hasConcept C153349607 @default.
• W2050433784 hasConcept C18051474 @default.
• W2050433784 hasConcept C185592680 @default.
• W2050433784 hasConcept C186060115 @default.
• W2050433784 hasConcept C19472624 @default.
• W2050433784 hasConcept C204328495 @default.
• W2050433784 hasConcept C2775937380 @default.
• W2050433784 hasConcept C2776545253 @default.
• W2050433784 hasConcept C2778112365 @default.
• W2050433784 hasConcept C2779281246 @default.
• W2050433784 hasConcept C47701112 @default.
• W2050433784 hasConcept C55493867 @default.

• next