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- W2050450969 abstract "The importance of distinguishing atypical cytoplasmic indirect immunofluorescence patterns from the “classic”, centrally accentuated cytoplasmic immunofluorescence pattern on ethanol fixed human neutrophils has recently been re-emphasised.1–3 Autoantibodies to other cytoplasmic autoantigens such as antimitochondrial antibodies (AMA), antismooth muscle antibodies, and antiribosomal-P antibodies have also recently been reported to produce atypical cytoplasmic immunofluorescence patterns on ethanol fixed human neutrophils.1 However, an alternative explanation is that the atypical cytoplasmic immunofluorescence patterns might be produced by concomitant antineutrophil cytoplasmic antibodies (ANCA) in these sera, especially in cases of autoimmune liver disease. Therefore, we investigated: (1) whether sera containing AMA with confirmed M2 specificity4 produced positive indirect immunofluorescence …" @default.
- W2050450969 created "2016-06-24" @default.
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- W2050450969 date "2000-08-01" @default.
- W2050450969 modified "2023-09-24" @default.
- W2050450969 title "M2-AMA do not directly produce ANCA indirect immunofluorescence patterns" @default.
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- W2050450969 doi "https://doi.org/10.1136/jcp.53.8.643" @default.
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