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- W2050451320 abstract "Five new guaiane-type sesquiterpenoids, hedyosumins A−E (1−5), together with five known ones (6−10), were isolated from the aerial parts of Hedyosmum orientale. Two known sesquiterpenoids, 10α-hydroxy-1,5αH-guaia-3,7(11)-dien-8α,12-olide and 9α-hydroxyasterolide, were obtained as natural products for the first time. Their structures were elucidated on the basis of spectroscopic methods. 9α-Hydroxyasterolide (7) showed moderate activities against A-549 and HL-60 tumor cell lines with the IC50 values of 3.1 and 8.8 μM, respectively." @default.
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- W2050451320 date "2008-07-24" @default.
- W2050451320 modified "2023-09-27" @default.
- W2050451320 title "Sesquiterpenoids from <i>Hedyosmum orientale</i>" @default.
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- W2050451320 doi "https://doi.org/10.1021/np800240v" @default.
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