FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050462022> ?p ?o ?g. }

• W2050462022 endingPage "191" @default.
• W2050462022 startingPage "186" @default.
• W2050462022 abstract "Biotransformation, metabolic enzyme profiles, and the glutathione antioxidant system in tiger salamanders (Ambystoma tigrinum) from a 14-day exposure to 2,4,6-trinitrotoluene (TNT) in situ were examined. Concentrations of parent compound and metabolites were measured in skin, kidney, and liver tissue. In addition, cytochrome P450 (P450) and cytochrome b5 content and their dependent isozyme activities, ethoxyresorufin O-dealkylation, pentoxyresorufin O-dealkylation, and the glutathione antioxidant system in the skin, liver, lung, kidneys, and blood were evaluated. Considerable differences were found in relative concentrations of TNT and its metabolites in the skin, relative to the liver and kidney. Trace amounts of TNT were detected only in the skin and liver of exposed animals while one of the secondary reduction metabolites, 2,6-diaminonitrotoluene, was found only in liver and kidney. Differences in the metabolite concentrations between systemic organs (liver, kidneys) and the skin suggest that the skin may be important in the primary reduction of TNT. In addition, measurable levels of these basal enzyme indicators were detected; yet of those evaluated only hepatic P450 content was affected by TNT exposure. The qualitative and quantitative differences in TNT and its metabolites in tissues suggest the fate and metabolism of the TNT in salamanders. Furthermore, results indicate that tiger salamanders possess considerable levels of xenobiotic metabolizing and antioxidant enzymes in these tissues but are not sensitive indicators of TNT exposure." @default.
• W2050462022 created "2016-06-24" @default.
• W2050462022 creator A5005297923 @default.
• W2050462022 creator A5028684975 @default.
• W2050462022 creator A5061134799 @default.
• W2050462022 creator A5075084768 @default.
• W2050462022 date "2000-06-01" @default.
• W2050462022 modified "2023-10-11" @default.
• W2050462022 title "Fate and the Biochemical Effects of 2,4,6-Trinitrotoluene Exposure to Tiger Salamanders (Ambystoma tigrinum)" @default.
• W2050462022 cites W1581414347 @default.
• W2050462022 cites W1951469402 @default.
• W2050462022 cites W1965318496 @default.
• W2050462022 cites W2004164398 @default.
• W2050462022 cites W2026261400 @default.
• W2050462022 cites W2033803470 @default.
• W2050462022 cites W2036254417 @default.
• W2050462022 cites W2039250271 @default.
• W2050462022 cites W2054955878 @default.
• W2050462022 cites W2060817230 @default.
• W2050462022 cites W2061331365 @default.
• W2050462022 cites W2068354294 @default.
• W2050462022 cites W2068643071 @default.
• W2050462022 cites W2078400065 @default.
• W2050462022 cites W2096426662 @default.
• W2050462022 cites W2114093436 @default.
• W2050462022 cites W2326902120 @default.
• W2050462022 doi "https://doi.org/10.1006/eesa.1999.1893" @default.
• W2050462022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10831332" @default.
• W2050462022 hasPublicationYear "2000" @default.
• W2050462022 type Work @default.
• W2050462022 sameAs 2050462022 @default.
• W2050462022 citedByCount "42" @default.
• W2050462022 countsByYear W20504620222012 @default.
• W2050462022 countsByYear W20504620222013 @default.
• W2050462022 countsByYear W20504620222014 @default.
• W2050462022 countsByYear W20504620222015 @default.
• W2050462022 countsByYear W20504620222017 @default.
• W2050462022 countsByYear W20504620222018 @default.
• W2050462022 crossrefType "journal-article" @default.
• W2050462022 hasAuthorship W2050462022A5005297923 @default.
• W2050462022 hasAuthorship W2050462022A5028684975 @default.
• W2050462022 hasAuthorship W2050462022A5061134799 @default.
• W2050462022 hasAuthorship W2050462022A5075084768 @default.
• W2050462022 hasConcept C115448650 @default.
• W2050462022 hasConcept C134018914 @default.
• W2050462022 hasConcept C154238967 @default.
• W2050462022 hasConcept C173758957 @default.
• W2050462022 hasConcept C178790620 @default.
• W2050462022 hasConcept C181199279 @default.
• W2050462022 hasConcept C185592680 @default.
• W2050462022 hasConcept C18903297 @default.
• W2050462022 hasConcept C2777477808 @default.
• W2050462022 hasConcept C2778004101 @default.
• W2050462022 hasConcept C2780091579 @default.
• W2050462022 hasConcept C27881333 @default.
• W2050462022 hasConcept C2909666209 @default.
• W2050462022 hasConcept C2910635913 @default.
• W2050462022 hasConcept C526171541 @default.
• W2050462022 hasConcept C538909803 @default.
• W2050462022 hasConcept C55493867 @default.
• W2050462022 hasConcept C62231903 @default.
• W2050462022 hasConcept C86803240 @default.
• W2050462022 hasConcept C89311334 @default.
• W2050462022 hasConceptScore W2050462022C115448650 @default.
• W2050462022 hasConceptScore W2050462022C134018914 @default.
• W2050462022 hasConceptScore W2050462022C154238967 @default.
• W2050462022 hasConceptScore W2050462022C173758957 @default.
• W2050462022 hasConceptScore W2050462022C178790620 @default.
• W2050462022 hasConceptScore W2050462022C181199279 @default.
• W2050462022 hasConceptScore W2050462022C185592680 @default.
• W2050462022 hasConceptScore W2050462022C18903297 @default.
• W2050462022 hasConceptScore W2050462022C2777477808 @default.
• W2050462022 hasConceptScore W2050462022C2778004101 @default.
• W2050462022 hasConceptScore W2050462022C2780091579 @default.
• W2050462022 hasConceptScore W2050462022C27881333 @default.
• W2050462022 hasConceptScore W2050462022C2909666209 @default.
• W2050462022 hasConceptScore W2050462022C2910635913 @default.
• W2050462022 hasConceptScore W2050462022C526171541 @default.
• W2050462022 hasConceptScore W2050462022C538909803 @default.
• W2050462022 hasConceptScore W2050462022C55493867 @default.
• W2050462022 hasConceptScore W2050462022C62231903 @default.
• W2050462022 hasConceptScore W2050462022C86803240 @default.
• W2050462022 hasConceptScore W2050462022C89311334 @default.
• W2050462022 hasIssue "2" @default.
• W2050462022 hasLocation W20504620221 @default.
• W2050462022 hasLocation W20504620222 @default.
• W2050462022 hasOpenAccess W2050462022 @default.
• W2050462022 hasPrimaryLocation W20504620221 @default.
• W2050462022 hasRelatedWork W135333318 @default.
• W2050462022 hasRelatedWork W138956189 @default.
• W2050462022 hasRelatedWork W1531940184 @default.
• W2050462022 hasRelatedWork W2020953047 @default.
• W2050462022 hasRelatedWork W2030261518 @default.
• W2050462022 hasRelatedWork W2050462022 @default.
• W2050462022 hasRelatedWork W2050771988 @default.
• W2050462022 hasRelatedWork W2164283682 @default.
• W2050462022 hasRelatedWork W2333731204 @default.
• W2050462022 hasRelatedWork W2968148069 @default.

• next