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• W2050492259 startingPage "1171" @default.
• W2050492259 abstract "Electron Paramagnetic Resonance (EPR, or ESR) is a powerful non-invasive spectroscopic tool that can be used to monitor drug release processes in vitro and in vivo. Furthermore, spatial dissolution can be achieved by means of EPR-Imaging. The article introduces the basics of EPR and EPR-imaging. It discusses also the challenges of in vivo spectroscopy and imaging and presents information about new developments such as longitudinally detected EPR (LODEPR) and Proton Electron Double Resonance Imaging ((PEDRI). Examples of the usefulness of EPR in the field of drug delivery include the measurement of microviscosity and micropolarity, the direct detection of drug release mechanisms in vitro and in vivo, the monitoring of microacidity in biodegradable polymers and the characterisation of colloidal drug carriers." @default.
• W2050492259 created "2016-06-24" @default.
• W2050492259 creator A5072378013 @default.
• W2050492259 creator A5083468442 @default.
• W2050492259 date "2005-06-15" @default.
• W2050492259 modified "2023-10-18" @default.
• W2050492259 title "Monitoring drug delivery processes by EPR and related techniques—principles and applications" @default.
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• W2050492259 doi "https://doi.org/10.1016/j.addr.2005.01.023" @default.
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