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- W2050496661 abstract "The pharmacological properties of [3H]7-hydroxy-N,N-di-n-propyl-2- aminotetralin ([3H]7-OH-DPAT) binding sites in the islands of Calleja of the rat were studied using quantitative receptor autoradiography. The KD and the Bmax values of [3H]7-OH-DPAT binding were about 1.6 nM and 100 fmol/mg protein, respectively. The rank order of potency was R(-)-propylnorapomorphine > 7-OH-DPAT approximately haloperidol > raclopride > dopamine > remoxipride. Remoxipride injected in vivo (0.03-100 mumol/kg i.p., 1 h before decapitation) did not inhibit subsequent [3H]7-OH-DPAT binding. These results indicate that the pharmacological profile of dopamine D3 receptors in the islands of Calleja of the rat resembles that obtained from cell lines or membrane preparations." @default.
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- W2050496661 date "1994-08-01" @default.
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- W2050496661 title "Pharmacology of dopamine D3 receptors in the islands of Calleja of the rat using quantitative receptor autoradiography" @default.
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- W2050496661 doi "https://doi.org/10.1016/0014-2999(94)90317-4" @default.
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