FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050530761> ?p ?o ?g. }

• W2050530761 endingPage "563" @default.
• W2050530761 startingPage "558" @default.
• W2050530761 abstract "The human immunodeficiency virus type 1 (HIV-1) HR-1 and HR-2 gp41 regions were sequenced in a total of 228 plasma or peripheral blood mononuclear cell samples obtained from an equal number of enfuvirtidenaive subjects for pol genotypic resistance testing in clinical practice. Phylogenetic analysis of the env sequences indicated that 102 belonged to subtype B and 95 to non-B subtypes (31 CRF02_AG, 21 F1, 14 C, 11 A1/A2/A3, 9 CRF01_AE, 9 others) while the remaining 31 were unique recombinant forms. There was considerable variability in the consensus sequence of different clades, particularly in HR-2. The HR-1 amino acid region 36–45, containing all of the enfuvirtide resistance mutations so far characterized, was well conserved except for position 42 where serine and asparagine were unevenly distributed in different subtypes. Enfuvirtide resistance mutations were not present in any sample, reinforcing the expectation that enfuvirtide is effective against many different HIV-1 clades and recombinants. However, some of the mutations outside the amino acid 36–45 region and provisionally suggested to play a role in modulating resistance were detected in a minority of cases. Molecular epidemiological surveys coupled with long-term observation of in vivo response to enfuvirtide and future fusion inhibitors are required to clarify the clinical significance of gp41 natural variability." @default.
• W2050530761 created "2016-06-24" @default.
• W2050530761 creator A5002487044 @default.
• W2050530761 creator A5032859619 @default.
• W2050530761 creator A5040843096 @default.
• W2050530761 creator A5050684950 @default.
• W2050530761 creator A5075069140 @default.
• W2050530761 creator A5087788423 @default.
• W2050530761 creator A5091290072 @default.
• W2050530761 date "2007-04-01" @default.
• W2050530761 modified "2023-10-17" @default.
• W2050530761 title "Natural Variability in the HR-1 and HR-2 Domains of HIV Type 1 gp41 from Different Clades Circulating in Italy" @default.
• W2050530761 cites W1507692039 @default.
• W2050530761 cites W1965600002 @default.
• W2050530761 cites W1996532819 @default.
• W2050530761 cites W2000495412 @default.
• W2050530761 cites W2016181192 @default.
• W2050530761 cites W2040506631 @default.
• W2050530761 cites W2047160382 @default.
• W2050530761 cites W2054945703 @default.
• W2050530761 cites W2079517309 @default.
• W2050530761 cites W2082363533 @default.
• W2050530761 cites W2082574239 @default.
• W2050530761 cites W2085739552 @default.
• W2050530761 cites W2087557525 @default.
• W2050530761 cites W2107672429 @default.
• W2050530761 cites W2108708014 @default.
• W2050530761 cites W2113396991 @default.
• W2050530761 cites W2120064320 @default.
• W2050530761 cites W2133649749 @default.
• W2050530761 cites W2146478787 @default.
• W2050530761 cites W2148591835 @default.
• W2050530761 cites W2169974120 @default.
• W2050530761 cites W2322165474 @default.
• W2050530761 doi "https://doi.org/10.1089/aid.2006.0273" @default.
• W2050530761 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17451345" @default.
• W2050530761 hasPublicationYear "2007" @default.
• W2050530761 type Work @default.
• W2050530761 sameAs 2050530761 @default.
• W2050530761 citedByCount "10" @default.
• W2050530761 countsByYear W20505307612012 @default.
• W2050530761 countsByYear W20505307612013 @default.
• W2050530761 crossrefType "journal-article" @default.
• W2050530761 hasAuthorship W2050530761A5002487044 @default.
• W2050530761 hasAuthorship W2050530761A5032859619 @default.
• W2050530761 hasAuthorship W2050530761A5040843096 @default.
• W2050530761 hasAuthorship W2050530761A5050684950 @default.
• W2050530761 hasAuthorship W2050530761A5075069140 @default.
• W2050530761 hasAuthorship W2050530761A5087788423 @default.
• W2050530761 hasAuthorship W2050530761A5091290072 @default.
• W2050530761 hasConcept C104317684 @default.
• W2050530761 hasConcept C135763542 @default.
• W2050530761 hasConcept C14500911 @default.
• W2050530761 hasConcept C147483822 @default.
• W2050530761 hasConcept C159047783 @default.
• W2050530761 hasConcept C167625842 @default.
• W2050530761 hasConcept C193252679 @default.
• W2050530761 hasConcept C195616568 @default.
• W2050530761 hasConcept C2522874641 @default.
• W2050530761 hasConcept C2775895851 @default.
• W2050530761 hasConcept C2776258796 @default.
• W2050530761 hasConcept C2776408679 @default.
• W2050530761 hasConcept C2778037500 @default.
• W2050530761 hasConcept C2779921545 @default.
• W2050530761 hasConcept C44465124 @default.
• W2050530761 hasConcept C515207424 @default.
• W2050530761 hasConcept C54355233 @default.
• W2050530761 hasConcept C86803240 @default.
• W2050530761 hasConceptScore W2050530761C104317684 @default.
• W2050530761 hasConceptScore W2050530761C135763542 @default.
• W2050530761 hasConceptScore W2050530761C14500911 @default.
• W2050530761 hasConceptScore W2050530761C147483822 @default.
• W2050530761 hasConceptScore W2050530761C159047783 @default.
• W2050530761 hasConceptScore W2050530761C167625842 @default.
• W2050530761 hasConceptScore W2050530761C193252679 @default.
• W2050530761 hasConceptScore W2050530761C195616568 @default.
• W2050530761 hasConceptScore W2050530761C2522874641 @default.
• W2050530761 hasConceptScore W2050530761C2775895851 @default.
• W2050530761 hasConceptScore W2050530761C2776258796 @default.
• W2050530761 hasConceptScore W2050530761C2776408679 @default.
• W2050530761 hasConceptScore W2050530761C2778037500 @default.
• W2050530761 hasConceptScore W2050530761C2779921545 @default.
• W2050530761 hasConceptScore W2050530761C44465124 @default.
• W2050530761 hasConceptScore W2050530761C515207424 @default.
• W2050530761 hasConceptScore W2050530761C54355233 @default.
• W2050530761 hasConceptScore W2050530761C86803240 @default.
• W2050530761 hasIssue "4" @default.
• W2050530761 hasLocation W20505307611 @default.
• W2050530761 hasLocation W20505307612 @default.
• W2050530761 hasOpenAccess W2050530761 @default.
• W2050530761 hasPrimaryLocation W20505307611 @default.
• W2050530761 hasRelatedWork W1551666225 @default.
• W2050530761 hasRelatedWork W1984826765 @default.
• W2050530761 hasRelatedWork W2050530761 @default.
• W2050530761 hasRelatedWork W2088837084 @default.
• W2050530761 hasRelatedWork W2111241578 @default.
• W2050530761 hasRelatedWork W2116416289 @default.
• W2050530761 hasRelatedWork W2141299808 @default.

• next