Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050541904> ?p ?o ?g. }
Showing items 1 to 87 of
87
with 100 items per page.
- W2050541904 abstract "1. The effect of methyl substitution in the alpha-carbon position of the ethanolamine side chain of INPEA was investigated on its beta-adrenoreceptor blocking activity in the isolated turtle heart and anaesthetized cats.2. In the turtle heart preparation, the pA(2) value for erythro-alpha-methyl INPEA was 5.3, as compared with 6.9 for INPEA, while threo-alpha-methyl INPEA was extremely weak and its pA(2) value could not be determined.3. In the intact cat experiments, alpha-methyl INPEA produced a competitive blockade of the peripheral vasodilator effect of isoprenaline in doses ranging from 5 to 20 mg/kg. However, this agent had a minimal effect on the cardiac stimulant effect of the catecholamine.4. These results are consistent with the hypothesis that the beta-adrenoreceptors comprise a family of nonhomogeneous receptors and a selective blockade of only some, but not all, responses mediated through their activation can be achieved by specific molecular modification of the beta-adrenoreceptor blocking agents." @default.
- W2050541904 created "2016-06-24" @default.
- W2050541904 creator A5062807186 @default.
- W2050541904 date "1969-11-01" @default.
- W2050541904 modified "2023-09-25" @default.
- W2050541904 title "Study on some selective β-adrenoreceptor blocking effects of 1-(4-nitrophenyl)-1-hydroxy-2-methyl isopropylaminoethane (α-methyl INPEA)" @default.
- W2050541904 cites W1873095075 @default.
- W2050541904 cites W1938287479 @default.
- W2050541904 cites W1938913382 @default.
- W2050541904 cites W1956898453 @default.
- W2050541904 cites W1979241855 @default.
- W2050541904 cites W1989988736 @default.
- W2050541904 cites W1996972993 @default.
- W2050541904 cites W2041608777 @default.
- W2050541904 cites W2057971042 @default.
- W2050541904 cites W2064088278 @default.
- W2050541904 cites W2086222449 @default.
- W2050541904 cites W2242781887 @default.
- W2050541904 cites W2257966633 @default.
- W2050541904 cites W2281938476 @default.
- W2050541904 cites W2332276211 @default.
- W2050541904 doi "https://doi.org/10.1111/j.1476-5381.1969.tb08499.x" @default.
- W2050541904 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1703724" @default.
- W2050541904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4390678" @default.
- W2050541904 hasPublicationYear "1969" @default.
- W2050541904 type Work @default.
- W2050541904 sameAs 2050541904 @default.
- W2050541904 citedByCount "8" @default.
- W2050541904 crossrefType "journal-article" @default.
- W2050541904 hasAuthorship W2050541904A5062807186 @default.
- W2050541904 hasBestOaLocation W20505419042 @default.
- W2050541904 hasConcept C120770815 @default.
- W2050541904 hasConcept C126322002 @default.
- W2050541904 hasConcept C134018914 @default.
- W2050541904 hasConcept C159110408 @default.
- W2050541904 hasConcept C170493617 @default.
- W2050541904 hasConcept C185592680 @default.
- W2050541904 hasConcept C199360897 @default.
- W2050541904 hasConcept C2775944032 @default.
- W2050541904 hasConcept C2776174256 @default.
- W2050541904 hasConcept C2778468042 @default.
- W2050541904 hasConcept C41008148 @default.
- W2050541904 hasConcept C49453240 @default.
- W2050541904 hasConcept C55493867 @default.
- W2050541904 hasConcept C64943373 @default.
- W2050541904 hasConcept C71240020 @default.
- W2050541904 hasConcept C71924100 @default.
- W2050541904 hasConcept C86803240 @default.
- W2050541904 hasConcept C98274493 @default.
- W2050541904 hasConceptScore W2050541904C120770815 @default.
- W2050541904 hasConceptScore W2050541904C126322002 @default.
- W2050541904 hasConceptScore W2050541904C134018914 @default.
- W2050541904 hasConceptScore W2050541904C159110408 @default.
- W2050541904 hasConceptScore W2050541904C170493617 @default.
- W2050541904 hasConceptScore W2050541904C185592680 @default.
- W2050541904 hasConceptScore W2050541904C199360897 @default.
- W2050541904 hasConceptScore W2050541904C2775944032 @default.
- W2050541904 hasConceptScore W2050541904C2776174256 @default.
- W2050541904 hasConceptScore W2050541904C2778468042 @default.
- W2050541904 hasConceptScore W2050541904C41008148 @default.
- W2050541904 hasConceptScore W2050541904C49453240 @default.
- W2050541904 hasConceptScore W2050541904C55493867 @default.
- W2050541904 hasConceptScore W2050541904C64943373 @default.
- W2050541904 hasConceptScore W2050541904C71240020 @default.
- W2050541904 hasConceptScore W2050541904C71924100 @default.
- W2050541904 hasConceptScore W2050541904C86803240 @default.
- W2050541904 hasConceptScore W2050541904C98274493 @default.
- W2050541904 hasLocation W20505419041 @default.
- W2050541904 hasLocation W20505419042 @default.
- W2050541904 hasLocation W20505419043 @default.
- W2050541904 hasLocation W20505419044 @default.
- W2050541904 hasOpenAccess W2050541904 @default.
- W2050541904 hasPrimaryLocation W20505419041 @default.
- W2050541904 hasRelatedWork W2073530579 @default.
- W2050541904 hasRelatedWork W2094341379 @default.
- W2050541904 hasRelatedWork W2099276421 @default.
- W2050541904 hasRelatedWork W2100236742 @default.
- W2050541904 hasRelatedWork W2110479013 @default.
- W2050541904 hasRelatedWork W2121464440 @default.
- W2050541904 hasRelatedWork W2133508058 @default.
- W2050541904 hasRelatedWork W2143398508 @default.
- W2050541904 hasRelatedWork W2166087715 @default.
- W2050541904 hasRelatedWork W60828312 @default.
- W2050541904 isParatext "false" @default.
- W2050541904 isRetracted "false" @default.
- W2050541904 magId "2050541904" @default.
- W2050541904 workType "article" @default.