Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050610003> ?p ?o ?g. }
- W2050610003 endingPage "384" @default.
- W2050610003 startingPage "377" @default.
- W2050610003 abstract "The side population (SP) phenotype, defined by the ability of a cell to efflux fluorescent dyes such as Hoechst, is common to several stem/progenitor cell types. In avian species, SP phenotype has been identified in pubertal and adult testes, but nothing is known about its expression during prenatal development of a male gonad. In this study, we characterized the Hoechst SP phenotype via the cytofluorimetric analysis of disaggregated testes on different days of chicken embryonic development. Male prenatal gonads contained a fraction of SP cells at each stage analyzed. At least two main SP fractions, named P3 and P4, were identified. The percentage of P3 fraction decreased as development proceeds, whereas P4 cell number was not affected by gonad growth. Functional inhibition of BCRP1 channel membrane using Verapamil and/or Ko143 showed that P3, but not P4 phenotype, was dependent on BCRP1 activity. Molecular analysis of both P3- and P4-sorted fractions revealed a differential RNA expression pattern, indicating that P3 cells mainly contained germinal stem cell markers, whereas P4 was preferentially composed of both Sertoli and Leydig cell progenitor markers. Finally, these findings provided evidence that the SP phenotype is a common feature of both germ and somatic cells detected in chicken developing testis." @default.
- W2050610003 created "2016-06-24" @default.
- W2050610003 creator A5006022808 @default.
- W2050610003 creator A5046742756 @default.
- W2050610003 creator A5069751419 @default.
- W2050610003 creator A5080541516 @default.
- W2050610003 date "2015-02-01" @default.
- W2050610003 modified "2023-10-18" @default.
- W2050610003 title "Identification of side population cells in chicken embryonic gonads" @default.
- W2050610003 cites W1483167997 @default.
- W2050610003 cites W1558400949 @default.
- W2050610003 cites W1660610441 @default.
- W2050610003 cites W1942686027 @default.
- W2050610003 cites W1968721773 @default.
- W2050610003 cites W1970690635 @default.
- W2050610003 cites W1972764534 @default.
- W2050610003 cites W1977434071 @default.
- W2050610003 cites W1985311481 @default.
- W2050610003 cites W1985772081 @default.
- W2050610003 cites W1993932646 @default.
- W2050610003 cites W1995403588 @default.
- W2050610003 cites W1999888302 @default.
- W2050610003 cites W2001459984 @default.
- W2050610003 cites W2004177477 @default.
- W2050610003 cites W2005849031 @default.
- W2050610003 cites W2011367566 @default.
- W2050610003 cites W2015975582 @default.
- W2050610003 cites W2018846644 @default.
- W2050610003 cites W2024173190 @default.
- W2050610003 cites W2026732645 @default.
- W2050610003 cites W2033953533 @default.
- W2050610003 cites W2037617072 @default.
- W2050610003 cites W2040812164 @default.
- W2050610003 cites W2048799419 @default.
- W2050610003 cites W2056027528 @default.
- W2050610003 cites W2062512555 @default.
- W2050610003 cites W2066551649 @default.
- W2050610003 cites W2073615544 @default.
- W2050610003 cites W2082210456 @default.
- W2050610003 cites W2084656538 @default.
- W2050610003 cites W2085588348 @default.
- W2050610003 cites W2091260939 @default.
- W2050610003 cites W2104562814 @default.
- W2050610003 cites W2110883354 @default.
- W2050610003 cites W2115410735 @default.
- W2050610003 cites W2117479891 @default.
- W2050610003 cites W2120344271 @default.
- W2050610003 cites W2121427472 @default.
- W2050610003 cites W2129832160 @default.
- W2050610003 cites W2135407093 @default.
- W2050610003 cites W2140034535 @default.
- W2050610003 cites W2150485214 @default.
- W2050610003 cites W2167226908 @default.
- W2050610003 cites W2168757635 @default.
- W2050610003 cites W2169072613 @default.
- W2050610003 cites W2169898367 @default.
- W2050610003 cites W2335803784 @default.
- W2050610003 doi "https://doi.org/10.1016/j.theriogenology.2014.09.029" @default.
- W2050610003 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25447150" @default.
- W2050610003 hasPublicationYear "2015" @default.
- W2050610003 type Work @default.
- W2050610003 sameAs 2050610003 @default.
- W2050610003 citedByCount "2" @default.
- W2050610003 countsByYear W20506100032017 @default.
- W2050610003 countsByYear W20506100032022 @default.
- W2050610003 crossrefType "journal-article" @default.
- W2050610003 hasAuthorship W2050610003A5006022808 @default.
- W2050610003 hasAuthorship W2050610003A5046742756 @default.
- W2050610003 hasAuthorship W2050610003A5069751419 @default.
- W2050610003 hasAuthorship W2050610003A5080541516 @default.
- W2050610003 hasConcept C104317684 @default.
- W2050610003 hasConcept C123765429 @default.
- W2050610003 hasConcept C126322002 @default.
- W2050610003 hasConcept C127716648 @default.
- W2050610003 hasConcept C134018914 @default.
- W2050610003 hasConcept C134305767 @default.
- W2050610003 hasConcept C144024400 @default.
- W2050610003 hasConcept C145103041 @default.
- W2050610003 hasConcept C149923435 @default.
- W2050610003 hasConcept C153911025 @default.
- W2050610003 hasConcept C16685009 @default.
- W2050610003 hasConcept C201750760 @default.
- W2050610003 hasConcept C2779122487 @default.
- W2050610003 hasConcept C2780546549 @default.
- W2050610003 hasConcept C2781068068 @default.
- W2050610003 hasConcept C2781471917 @default.
- W2050610003 hasConcept C28328180 @default.
- W2050610003 hasConcept C2908647359 @default.
- W2050610003 hasConcept C54355233 @default.
- W2050610003 hasConcept C71924100 @default.
- W2050610003 hasConcept C86803240 @default.
- W2050610003 hasConcept C95444343 @default.
- W2050610003 hasConceptScore W2050610003C104317684 @default.
- W2050610003 hasConceptScore W2050610003C123765429 @default.
- W2050610003 hasConceptScore W2050610003C126322002 @default.
- W2050610003 hasConceptScore W2050610003C127716648 @default.
- W2050610003 hasConceptScore W2050610003C134018914 @default.
- W2050610003 hasConceptScore W2050610003C134305767 @default.