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- W2050615251 abstract "Billions of basepairs of DNA can be sequenced in hours using a nanopore technology being developed in a collaboration between Harvard University and Agilent Technologies Inc. The device is composed of a silicon nitride membrane with two-nm pores that allow long strands of DNA to pass through at 1000 bases per second. As the DNA strand goes through the membrane, subtle changes in electrical current can be measured that are related to the composition of the DNA. A prototype membrane allowed a DNA strand of 30 000 basepairs to pass through. Although this device cannot differentiate individual nucleotides yet, Daniel Branton, leader of the Harvard team is confident that this could be achieved within five years. If successfully completed, such a device could perhaps be used to provide a complete genomic profile to a doctor within a matter of hours – allowing a complete diagnosis or determining a patient's susceptibility to drug side effects, for instance. (http://www.business2.com/articles/mag/print/0,1643,16900,00.html) AP" @default.
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- W2050615251 date "2001-11-01" @default.
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- W2050615251 title "Genome sequencing in a day" @default.
- W2050615251 doi "https://doi.org/10.1016/s0168-9525(01)02540-9" @default.
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