Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050615539> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2050615539 endingPage "110" @default.
- W2050615539 startingPage "106" @default.
- W2050615539 abstract "In order to formulate a thoughtful and rational approach to drug dosing in renal failure, the nephrologist must consider several features that influence drug disposition in uremia. Drug bioavailability is generally adversely influenced in patients with renal disease. Drug distribution is frequently altered to an unpredictable degree. Drug protein binding is affected not only by changes in the amount of circulating binding protein but also by the accumulation of endogenous toxins. Renal failure frequently affects drug biotransformation. Drug-dosing tables and nomograms are important; however, they are not a substitute for an encompassing clinical approach and sound clinical judgment. In order to formulate a thoughtful and rational approach to drug dosing in renal failure, the nephrologist must consider several features that influence drug disposition in uremia. Drug bioavailability is generally adversely influenced in patients with renal disease. Drug distribution is frequently altered to an unpredictable degree. Drug protein binding is affected not only by changes in the amount of circulating binding protein but also by the accumulation of endogenous toxins. Renal failure frequently affects drug biotransformation. Drug-dosing tables and nomograms are important; however, they are not a substitute for an encompassing clinical approach and sound clinical judgment." @default.
- W2050615539 created "2016-06-24" @default.
- W2050615539 creator A5031129081 @default.
- W2050615539 date "1983-09-01" @default.
- W2050615539 modified "2023-09-26" @default.
- W2050615539 title "Antimicrobial Therapy in Patients With Impaired Renal Function" @default.
- W2050615539 cites W1978979619 @default.
- W2050615539 cites W1986571696 @default.
- W2050615539 cites W2059556620 @default.
- W2050615539 cites W2060835050 @default.
- W2050615539 cites W2067241022 @default.
- W2050615539 cites W2091529897 @default.
- W2050615539 cites W2091713746 @default.
- W2050615539 doi "https://doi.org/10.1016/s0272-6386(83)80023-7" @default.
- W2050615539 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6613989" @default.
- W2050615539 hasPublicationYear "1983" @default.
- W2050615539 type Work @default.
- W2050615539 sameAs 2050615539 @default.
- W2050615539 citedByCount "8" @default.
- W2050615539 countsByYear W20506155392018 @default.
- W2050615539 crossrefType "journal-article" @default.
- W2050615539 hasAuthorship W2050615539A5031129081 @default.
- W2050615539 hasConcept C110121322 @default.
- W2050615539 hasConcept C112705442 @default.
- W2050615539 hasConcept C126322002 @default.
- W2050615539 hasConcept C134306372 @default.
- W2050615539 hasConcept C177713679 @default.
- W2050615539 hasConcept C181389837 @default.
- W2050615539 hasConcept C2776635150 @default.
- W2050615539 hasConcept C2777288759 @default.
- W2050615539 hasConcept C2780035454 @default.
- W2050615539 hasConcept C33923547 @default.
- W2050615539 hasConcept C54847362 @default.
- W2050615539 hasConcept C71924100 @default.
- W2050615539 hasConcept C98274493 @default.
- W2050615539 hasConceptScore W2050615539C110121322 @default.
- W2050615539 hasConceptScore W2050615539C112705442 @default.
- W2050615539 hasConceptScore W2050615539C126322002 @default.
- W2050615539 hasConceptScore W2050615539C134306372 @default.
- W2050615539 hasConceptScore W2050615539C177713679 @default.
- W2050615539 hasConceptScore W2050615539C181389837 @default.
- W2050615539 hasConceptScore W2050615539C2776635150 @default.
- W2050615539 hasConceptScore W2050615539C2777288759 @default.
- W2050615539 hasConceptScore W2050615539C2780035454 @default.
- W2050615539 hasConceptScore W2050615539C33923547 @default.
- W2050615539 hasConceptScore W2050615539C54847362 @default.
- W2050615539 hasConceptScore W2050615539C71924100 @default.
- W2050615539 hasConceptScore W2050615539C98274493 @default.
- W2050615539 hasIssue "2" @default.
- W2050615539 hasLocation W20506155391 @default.
- W2050615539 hasLocation W20506155392 @default.
- W2050615539 hasOpenAccess W2050615539 @default.
- W2050615539 hasPrimaryLocation W20506155391 @default.
- W2050615539 hasRelatedWork W1555144605 @default.
- W2050615539 hasRelatedWork W1969876219 @default.
- W2050615539 hasRelatedWork W2004325424 @default.
- W2050615539 hasRelatedWork W2009820498 @default.
- W2050615539 hasRelatedWork W2030105938 @default.
- W2050615539 hasRelatedWork W2744667494 @default.
- W2050615539 hasRelatedWork W2793520024 @default.
- W2050615539 hasRelatedWork W2992077105 @default.
- W2050615539 hasRelatedWork W3024440267 @default.
- W2050615539 hasRelatedWork W4320061796 @default.
- W2050615539 hasVolume "3" @default.
- W2050615539 isParatext "false" @default.
- W2050615539 isRetracted "false" @default.
- W2050615539 magId "2050615539" @default.
- W2050615539 workType "article" @default.