FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050649679> ?p ?o ?g. }

• W2050649679 endingPage "6386" @default.
• W2050649679 startingPage "6379" @default.
• W2050649679 abstract "The synthesis and pharmacological characterization of a novel furan-based class of voltage-gated sodium channel blockers is reported. Compounds were evaluated for their ability to block the tetrodotoxin-resistant sodium channel Nav1.8 (PN3) as well as the Nav1.2 and Nav1.5 subtypes. Benchmark compounds from this series possessed enhanced potency, oral bioavailability, and robust efficacy in a rodent model of neuropathic pain, together with improved CNS and cardiovascular safety profiles compared to the clinically used sodium channel blockers mexiletine and lamotrigine." @default.
• W2050649679 created "2016-06-24" @default.
• W2050649679 creator A5007044838 @default.
• W2050649679 creator A5008043477 @default.
• W2050649679 creator A5010578556 @default.
• W2050649679 creator A5015368950 @default.
• W2050649679 creator A5019347322 @default.
• W2050649679 creator A5021142717 @default.
• W2050649679 creator A5026852803 @default.
• W2050649679 creator A5027480234 @default.
• W2050649679 creator A5028708112 @default.
• W2050649679 creator A5031533475 @default.
• W2050649679 creator A5032395863 @default.
• W2050649679 creator A5037329008 @default.
• W2050649679 creator A5040757035 @default.
• W2050649679 creator A5056036725 @default.
• W2050649679 creator A5058616888 @default.
• W2050649679 creator A5061348725 @default.
• W2050649679 creator A5067147097 @default.
• W2050649679 creator A5068391373 @default.
• W2050649679 creator A5070193297 @default.
• W2050649679 creator A5072770811 @default.
• W2050649679 creator A5073001403 @default.
• W2050649679 creator A5080635647 @default.
• W2050649679 creator A5085452913 @default.
• W2050649679 creator A5087064357 @default.
• W2050649679 creator A5088396379 @default.
• W2050649679 creator A5088407789 @default.
• W2050649679 creator A5089248430 @default.
• W2050649679 creator A5082542295 @default.
• W2050649679 date "2008-06-01" @default.
• W2050649679 modified "2023-10-17" @default.
• W2050649679 title "Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain" @default.
• W2050649679 cites W1506534827 @default.
• W2050649679 cites W1549160512 @default.
• W2050649679 cites W1965866432 @default.
• W2050649679 cites W1983187084 @default.
• W2050649679 cites W1999347938 @default.
• W2050649679 cites W2000178071 @default.
• W2050649679 cites W2018071187 @default.
• W2050649679 cites W2018368852 @default.
• W2050649679 cites W2029665144 @default.
• W2050649679 cites W2032809866 @default.
• W2050649679 cites W2037311556 @default.
• W2050649679 cites W2041387480 @default.
• W2050649679 cites W2049710812 @default.
• W2050649679 cites W2051997075 @default.
• W2050649679 cites W2065857917 @default.
• W2050649679 cites W2066962218 @default.
• W2050649679 cites W2082470319 @default.
• W2050649679 cites W2098158295 @default.
• W2050649679 cites W2106753138 @default.
• W2050649679 cites W2130496291 @default.
• W2050649679 cites W2145540995 @default.
• W2050649679 cites W2175812203 @default.
• W2050649679 cites W2949367276 @default.
• W2050649679 cites W3146417683 @default.
• W2050649679 cites W40340874 @default.
• W2050649679 doi "https://doi.org/10.1016/j.bmc.2008.05.003" @default.
• W2050649679 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18501613" @default.
• W2050649679 hasPublicationYear "2008" @default.
• W2050649679 type Work @default.
• W2050649679 sameAs 2050649679 @default.
• W2050649679 citedByCount "19" @default.
• W2050649679 countsByYear W20506496792012 @default.
• W2050649679 countsByYear W20506496792013 @default.
• W2050649679 countsByYear W20506496792017 @default.
• W2050649679 countsByYear W20506496792019 @default.
• W2050649679 countsByYear W20506496792021 @default.
• W2050649679 crossrefType "journal-article" @default.
• W2050649679 hasAuthorship W2050649679A5007044838 @default.
• W2050649679 hasAuthorship W2050649679A5008043477 @default.
• W2050649679 hasAuthorship W2050649679A5010578556 @default.
• W2050649679 hasAuthorship W2050649679A5015368950 @default.
• W2050649679 hasAuthorship W2050649679A5019347322 @default.
• W2050649679 hasAuthorship W2050649679A5021142717 @default.
• W2050649679 hasAuthorship W2050649679A5026852803 @default.
• W2050649679 hasAuthorship W2050649679A5027480234 @default.
• W2050649679 hasAuthorship W2050649679A5028708112 @default.
• W2050649679 hasAuthorship W2050649679A5031533475 @default.
• W2050649679 hasAuthorship W2050649679A5032395863 @default.
• W2050649679 hasAuthorship W2050649679A5037329008 @default.
• W2050649679 hasAuthorship W2050649679A5040757035 @default.
• W2050649679 hasAuthorship W2050649679A5056036725 @default.
• W2050649679 hasAuthorship W2050649679A5058616888 @default.
• W2050649679 hasAuthorship W2050649679A5061348725 @default.
• W2050649679 hasAuthorship W2050649679A5067147097 @default.
• W2050649679 hasAuthorship W2050649679A5068391373 @default.
• W2050649679 hasAuthorship W2050649679A5070193297 @default.
• W2050649679 hasAuthorship W2050649679A5072770811 @default.
• W2050649679 hasAuthorship W2050649679A5073001403 @default.
• W2050649679 hasAuthorship W2050649679A5080635647 @default.
• W2050649679 hasAuthorship W2050649679A5082542295 @default.
• W2050649679 hasAuthorship W2050649679A5085452913 @default.
• W2050649679 hasAuthorship W2050649679A5087064357 @default.
• W2050649679 hasAuthorship W2050649679A5088396379 @default.
• W2050649679 hasAuthorship W2050649679A5088407789 @default.
• W2050649679 hasAuthorship W2050649679A5089248430 @default.

• next