Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050661504> ?p ?o ?g. }
- W2050661504 endingPage "196" @default.
- W2050661504 startingPage "190" @default.
- W2050661504 abstract "Suppressor of cytokine signaling‐1 (SOCS1) was identified as the negative regulator of Janus kinase (JAK) and signal transducer and activator of transcription (STAT) signal transduction pathway. However, the kinetics and control mechanism of the pathway have not yet been fully understood. We have developed the computer simulation of the JAK/STAT pathway. Without nuclear phosphatase, SOCS1's binding to JAK did not cause the decrease in nuclear phosphorylated STAT1. However, without SH2 domain‐containing tyrosine phosphatase 2 (SHP‐2) or cytoplasmic phosphatase, it did. So nuclear phosphatase is considered to be the most important in this system. By changing parameters of the model, dynamical characteristics and control mechanism were investigated." @default.
- W2050661504 created "2016-06-24" @default.
- W2050661504 creator A5014972376 @default.
- W2050661504 creator A5031427780 @default.
- W2050661504 creator A5069604849 @default.
- W2050661504 creator A5080731356 @default.
- W2050661504 date "2002-12-23" @default.
- W2050661504 modified "2023-10-09" @default.
- W2050661504 title "Control mechanism of JAK/STAT signal transduction pathway" @default.
- W2050661504 cites W1488478985 @default.
- W2050661504 cites W1980396134 @default.
- W2050661504 cites W1981299945 @default.
- W2050661504 cites W1983974405 @default.
- W2050661504 cites W1990736894 @default.
- W2050661504 cites W2000583211 @default.
- W2050661504 cites W2002220979 @default.
- W2050661504 cites W2007199665 @default.
- W2050661504 cites W2027905684 @default.
- W2050661504 cites W2030624761 @default.
- W2050661504 cites W2034286443 @default.
- W2050661504 cites W2043803403 @default.
- W2050661504 cites W2044522714 @default.
- W2050661504 cites W2048051867 @default.
- W2050661504 cites W2085935547 @default.
- W2050661504 cites W2108486371 @default.
- W2050661504 cites W2114990619 @default.
- W2050661504 cites W2119733834 @default.
- W2050661504 cites W2124489640 @default.
- W2050661504 cites W2144776072 @default.
- W2050661504 cites W2147511779 @default.
- W2050661504 cites W2152000177 @default.
- W2050661504 doi "https://doi.org/10.1016/s0014-5793(02)03842-5" @default.
- W2050661504 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12527385" @default.
- W2050661504 hasPublicationYear "2002" @default.
- W2050661504 type Work @default.
- W2050661504 sameAs 2050661504 @default.
- W2050661504 citedByCount "178" @default.
- W2050661504 countsByYear W20506615042012 @default.
- W2050661504 countsByYear W20506615042013 @default.
- W2050661504 countsByYear W20506615042014 @default.
- W2050661504 countsByYear W20506615042015 @default.
- W2050661504 countsByYear W20506615042016 @default.
- W2050661504 countsByYear W20506615042017 @default.
- W2050661504 countsByYear W20506615042018 @default.
- W2050661504 countsByYear W20506615042019 @default.
- W2050661504 countsByYear W20506615042020 @default.
- W2050661504 countsByYear W20506615042021 @default.
- W2050661504 countsByYear W20506615042022 @default.
- W2050661504 countsByYear W20506615042023 @default.
- W2050661504 crossrefType "journal-article" @default.
- W2050661504 hasAuthorship W2050661504A5014972376 @default.
- W2050661504 hasAuthorship W2050661504A5031427780 @default.
- W2050661504 hasAuthorship W2050661504A5069604849 @default.
- W2050661504 hasAuthorship W2050661504A5080731356 @default.
- W2050661504 hasBestOaLocation W20506615041 @default.
- W2050661504 hasConcept C104317684 @default.
- W2050661504 hasConcept C112392421 @default.
- W2050661504 hasConcept C11960822 @default.
- W2050661504 hasConcept C126042315 @default.
- W2050661504 hasConcept C14077384 @default.
- W2050661504 hasConcept C157333092 @default.
- W2050661504 hasConcept C171958077 @default.
- W2050661504 hasConcept C178666793 @default.
- W2050661504 hasConcept C179185449 @default.
- W2050661504 hasConcept C185592680 @default.
- W2050661504 hasConcept C2778277574 @default.
- W2050661504 hasConcept C2778923194 @default.
- W2050661504 hasConcept C42362537 @default.
- W2050661504 hasConcept C55493867 @default.
- W2050661504 hasConcept C62478195 @default.
- W2050661504 hasConcept C85528070 @default.
- W2050661504 hasConcept C86803240 @default.
- W2050661504 hasConcept C95444343 @default.
- W2050661504 hasConceptScore W2050661504C104317684 @default.
- W2050661504 hasConceptScore W2050661504C112392421 @default.
- W2050661504 hasConceptScore W2050661504C11960822 @default.
- W2050661504 hasConceptScore W2050661504C126042315 @default.
- W2050661504 hasConceptScore W2050661504C14077384 @default.
- W2050661504 hasConceptScore W2050661504C157333092 @default.
- W2050661504 hasConceptScore W2050661504C171958077 @default.
- W2050661504 hasConceptScore W2050661504C178666793 @default.
- W2050661504 hasConceptScore W2050661504C179185449 @default.
- W2050661504 hasConceptScore W2050661504C185592680 @default.
- W2050661504 hasConceptScore W2050661504C2778277574 @default.
- W2050661504 hasConceptScore W2050661504C2778923194 @default.
- W2050661504 hasConceptScore W2050661504C42362537 @default.
- W2050661504 hasConceptScore W2050661504C55493867 @default.
- W2050661504 hasConceptScore W2050661504C62478195 @default.
- W2050661504 hasConceptScore W2050661504C85528070 @default.
- W2050661504 hasConceptScore W2050661504C86803240 @default.
- W2050661504 hasConceptScore W2050661504C95444343 @default.
- W2050661504 hasIssue "1-3" @default.
- W2050661504 hasLocation W20506615041 @default.
- W2050661504 hasLocation W20506615042 @default.
- W2050661504 hasOpenAccess W2050661504 @default.
- W2050661504 hasPrimaryLocation W20506615041 @default.
- W2050661504 hasRelatedWork W2007199665 @default.
- W2050661504 hasRelatedWork W2008023169 @default.