FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2050681327> ?p ?o ?g. }

• W2050681327 endingPage "86" @default.
• W2050681327 startingPage "80" @default.
• W2050681327 abstract "To assess the risks and benefits of menopausal hormone replacement therapy, we followed a 23,246-member, population-based cohort of Swedish women who were prescribed menopausal estrogens for an average of 8.6 years for mortality. Compared with the general population, the standardized mortality ratio for all-cause mortality in this cohort was 0.77 (95% confidence limits = 0.73, 0.81). Deaths in each of the 12 major categories of causes of death except for injuries occurred 12% to 86% less frequently than expected. We examined in detail four specific causes of death according to the type of hormone prescribed, namely weak estrogens (primarily estriol), more potent estrogens (primarily estradiol and conjugated estrogens) in combination with a progestin, and more potent estrogens without a progestin. Mortality from endometrial cancer was not related to the prescription of weak estrogens or an estrogen-progestin combination, but mortality was 40% higher in women prescribed more potent estrogens without a progestin. Women prescribed weak estrogens, more potent estrogens, and the combined estrogen-progestin regimen were at reduced risk of death from ischemic heart disease (standardized mortality ratios of 0.7, 0.6, and 0.4, respectively). The more potent estrogens and the estrogen-progestin combination were associated with a marked reduction in risk of intracerebral hemorrhage (standardized mortality ratios of 0.4 and 0.6, respectively) and “other” cerebrovascular disease, but not other types of stroke. The concern that use of progestins would lead to psychic disorders related to suicide received no support from our results. Breast cancer results are described elsewhere. These data provide little evidence of an adverse effect of the combined estrogen-progestin regimen as compared with estrogens alone on mortality. They do indicate, however, that both selection factors and biology may contribute to the almost across-the-board-reduction in mortality associated with hormone replacement therapy." @default.
• W2050681327 created "2016-06-24" @default.
• W2050681327 creator A5055344765 @default.
• W2050681327 date "1997-01-01" @default.
• W2050681327 modified "2023-09-25" @default.
• W2050681327 title "Causal Modeling to Estimate Sensitivity and Specificity of a Test when Prevalence Changes" @default.
• W2050681327 cites W133188458 @default.
• W2050681327 cites W1532849523 @default.
• W2050681327 cites W1555798572 @default.
• W2050681327 cites W1577273168 @default.
• W2050681327 cites W1607190847 @default.
• W2050681327 cites W1968300278 @default.
• W2050681327 cites W1985520316 @default.
• W2050681327 cites W1987680624 @default.
• W2050681327 cites W1989945919 @default.
• W2050681327 cites W1997495899 @default.
• W2050681327 cites W2063869724 @default.
• W2050681327 cites W2077610722 @default.
• W2050681327 cites W207852645 @default.
• W2050681327 cites W2092031593 @default.
• W2050681327 cites W2105862813 @default.
• W2050681327 cites W2130399147 @default.
• W2050681327 cites W2160193857 @default.
• W2050681327 cites W2302785252 @default.
• W2050681327 cites W2309169278 @default.
• W2050681327 cites W2329414964 @default.
• W2050681327 cites W2334748255 @default.
• W2050681327 cites W2339492498 @default.
• W2050681327 cites W2340399630 @default.
• W2050681327 cites W2341139907 @default.
• W2050681327 cites W2400004712 @default.
• W2050681327 cites W2578765318 @default.
• W2050681327 cites W304998534 @default.
• W2050681327 cites W3083113686 @default.
• W2050681327 cites W639118616 @default.
• W2050681327 doi "https://doi.org/10.1097/00001648-199701000-00013" @default.
• W2050681327 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9116101" @default.
• W2050681327 hasPublicationYear "1997" @default.
• W2050681327 type Work @default.
• W2050681327 sameAs 2050681327 @default.
• W2050681327 citedByCount "26" @default.
• W2050681327 countsByYear W20506813272013 @default.
• W2050681327 countsByYear W20506813272014 @default.
• W2050681327 countsByYear W20506813272015 @default.
• W2050681327 countsByYear W20506813272017 @default.
• W2050681327 countsByYear W20506813272019 @default.
• W2050681327 countsByYear W20506813272020 @default.
• W2050681327 countsByYear W20506813272023 @default.
• W2050681327 crossrefType "journal-article" @default.
• W2050681327 hasAuthorship W2050681327A5055344765 @default.
• W2050681327 hasConcept C102803821 @default.
• W2050681327 hasConcept C126322002 @default.
• W2050681327 hasConcept C134018914 @default.
• W2050681327 hasConcept C2776607906 @default.
• W2050681327 hasConcept C2777164284 @default.
• W2050681327 hasConcept C2777335581 @default.
• W2050681327 hasConcept C2779134260 @default.
• W2050681327 hasConcept C2908647359 @default.
• W2050681327 hasConcept C29374701 @default.
• W2050681327 hasConcept C29456083 @default.
• W2050681327 hasConcept C42407357 @default.
• W2050681327 hasConcept C71924100 @default.
• W2050681327 hasConcept C72563966 @default.
• W2050681327 hasConcept C99454951 @default.
• W2050681327 hasConceptScore W2050681327C102803821 @default.
• W2050681327 hasConceptScore W2050681327C126322002 @default.
• W2050681327 hasConceptScore W2050681327C134018914 @default.
• W2050681327 hasConceptScore W2050681327C2776607906 @default.
• W2050681327 hasConceptScore W2050681327C2777164284 @default.
• W2050681327 hasConceptScore W2050681327C2777335581 @default.
• W2050681327 hasConceptScore W2050681327C2779134260 @default.
• W2050681327 hasConceptScore W2050681327C2908647359 @default.
• W2050681327 hasConceptScore W2050681327C29374701 @default.
• W2050681327 hasConceptScore W2050681327C29456083 @default.
• W2050681327 hasConceptScore W2050681327C42407357 @default.
• W2050681327 hasConceptScore W2050681327C71924100 @default.
• W2050681327 hasConceptScore W2050681327C72563966 @default.
• W2050681327 hasConceptScore W2050681327C99454951 @default.
• W2050681327 hasIssue "1" @default.
• W2050681327 hasLocation W20506813271 @default.
• W2050681327 hasLocation W20506813272 @default.
• W2050681327 hasOpenAccess W2050681327 @default.
• W2050681327 hasPrimaryLocation W20506813271 @default.
• W2050681327 hasRelatedWork W1963710704 @default.
• W2050681327 hasRelatedWork W1970655517 @default.
• W2050681327 hasRelatedWork W1995647897 @default.
• W2050681327 hasRelatedWork W2013481652 @default.
• W2050681327 hasRelatedWork W2027180407 @default.
• W2050681327 hasRelatedWork W2101821182 @default.
• W2050681327 hasRelatedWork W2109375501 @default.
• W2050681327 hasRelatedWork W2109882125 @default.
• W2050681327 hasRelatedWork W2168803779 @default.
• W2050681327 hasRelatedWork W4232275671 @default.
• W2050681327 hasVolume "8" @default.
• W2050681327 isParatext "false" @default.
• W2050681327 isRetracted "false" @default.
• W2050681327 magId "2050681327" @default.
• W2050681327 workType "article" @default.